Volume 28 Issue 10 2023

• Open Access Original Research

  Identification of Key Novel lncRNAs RP11-400N13.3 and RP11-197K6.1 that Construct ceRNA Networks Associated with Recurrence and Metastasis in Colon Cancer

  Yan Wang, Xing-hai Zhang, Si-hua Xie, Lu-lu Yang, ... Fan-hao Meng

  Front. Biosci. (Landmark Ed) 2023, 28(10), 276; https://doi.org/10.31083/j.fbl2810276

  Abstract Full Text PDF(3.25MB)

  31

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  146

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• Open Access Original Research

  Heme Oxygenase-1 Alleviates Ischemia-Reperfusion Injury by Inhibiting Hepatocyte Pyroptosis after Liver Transplantation in Rats

  Tao Wang, Yuan Fang, Xiaoli Zhang, Yang Yang, ... Hanfei Huang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 275; https://doi.org/10.31083/j.fbl2810275

  (This article belongs to the Special Issue Mechanisms of Protection and/or Therapy for Ischemia and Reperfusion Injury in the Brain, Spinal Cord, Heart, Liver, and Kidney)

  Abstract Full Text PDF(9.64MB)

  19

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  94

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• Open Access Review

  Mechanical Signaling in Dental Pulp Stem Cells

  Jiahe Zhao, Wen Du, Daimo Guo, Siyi Wang, Wei Du

  Front. Biosci. (Landmark Ed) 2023, 28(10), 274; https://doi.org/10.31083/j.fbl2810274

  (This article belongs to the Special Issue Advances of Molecular Sciences in Oral Diseases Detection and Treatment)

  Abstract Full Text PDF(594.32KB)

  48

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  142

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• Open Access Review

  SARS-CoV-2: The Virus, Its Biology and COVID-19 Disease-Counteracting Possibilities

  Rolf Marschalek

  Front. Biosci. (Landmark Ed) 2023, 28(10), 273; https://doi.org/10.31083/j.fbl2810273

  (This article belongs to the Special Issue Immunology in COVID-19 Disease)

  Abstract Full Text PDF(7.23MB)

  82

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  256

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• Open Access Original Research

  Extrahepatic Angiogenesis: A Potential Common Pathophysiological Basis of Multiple Organ Dysfunction in Rats with Cholestasis Cirrhosis

  Dandan Wang, Chunyong Yang, Ziyang Zeng, Xianfeng Wu, ... Bin Yi

  Front. Biosci. (Landmark Ed) 2023, 28(10), 272; https://doi.org/10.31083/j.fbl2810272

  Abstract Full Text PDF(9.63MB)

  27

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  123

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• Open Access Original Research

  The EMT-Related Genes GALNT3 and OAS1 are Associated with Immune Cell Infiltration and Poor Prognosis in Lung Adenocarcinoma

  Dan Luo, Mengying Fang, Le Shao, Jue Wang, ... Qibiao Wu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 271; https://doi.org/10.31083/j.fbl2810271

  (This article belongs to the Special Issue New Insights against Cancer Progression and Metastasis)

  Abstract Full Text PDF(4.52MB)

  36

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  152

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• Open Access Original Research

  LncRNA PART1 Regulates Ovarian Carcinoma Development via the miR-150-5p/MYB Axis

  Jing Wang, Yun Han, Tingting Zhang, Jing Li, Boqun Xu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 270; https://doi.org/10.31083/j.fbl2810270

  (This article belongs to the Special Issue Diagnostic, Prognostic, and Therapeutic Biomarkers for Ovarian Cancer)

  Abstract Full Text PDF(4.30MB)

  20

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  126

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• Open Access Review

  Microglia and Stem Cells for Ischemic Stroke Treatment—Mechanisms, Current Status, and Therapeutic Challenges

  Aleksandra Markowska, Dariusz Koziorowski, Stanisław Szlufik

  Front. Biosci. (Landmark Ed) 2023, 28(10), 269; https://doi.org/10.31083/j.fbl2810269

  (This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

  Abstract Full Text PDF(474.57KB)

  74

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  205

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• Open Access Original Research

  Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells

  Sheyda Najafi, Leonard Barasa, Jilian Maxine J. Frianela, Jawaher H. Alkhamisy, ... Jeanette C. Perron

  Front. Biosci. (Landmark Ed) 2023, 28(10), 268; https://doi.org/10.31083/j.fbl2810268

  (This article belongs to the Special Issue Regulation of Osteoclast Differentiation)

  Abstract Full Text PDF(4.68MB)

  20

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  171

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• Open Access Short Communication

  Comparative Transcriptomic Profiling in Ovarian Tissues of Lohmann Hens and Chengkou Mountain Chicken

  Zhuanyun Wang, Guangxin E, Chengli Liu, Changbao Liu, ... Minghui Li

  Front. Biosci. (Landmark Ed) 2023, 28(10), 267; https://doi.org/10.31083/j.fbl2810267

  Abstract Full Text PDF(5.74MB)

  21

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  90

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• Open Access Review

  Modulation of Alpha-Synuclein Conformational Ensemble and Aggregation Pathways by Dopamine and Related Molecules

  Antonino Natalello, Stefania Brocca, Erika Ponzini, Carlo Santambrogio, Rita Grandori

  Front. Biosci. (Landmark Ed) 2023, 28(10), 266; https://doi.org/10.31083/j.fbl2810266

  (This article belongs to the Special Issue From protein misfolding to dementia: basic research, innovative diagnosis and early biomarkers)

  Abstract Full Text PDF(3.19MB)

  35

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  125

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• Open Access Review

  Etiology of Oral Potentially Malignant Disorders and Squamous Cell Carcinoma Based on Cellular Stress Regulation and Matrix Stiffness

  Toshihiro Hasegawa, Takehito Ouchi, Yoshiyuki Shibukawa, Seiji Asoda, Taneaki Nakagawa

  Front. Biosci. (Landmark Ed) 2023, 28(10), 265; https://doi.org/10.31083/j.fbl2810265

  (This article belongs to the Special Issue Development and Physiological Functions of Cancer Stem Cells)

  Abstract Full Text PDF(2.38MB)

  32

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  173

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• Open Access Original Research

  Unveiling the Impact of Thiophanate-Methyl on Arthrospira platensis: Growth, Photosynthetic Pigments, Biomolecules, and Detoxification Enzyme Activities

  Nabil Touzout, Mahfoud Ainas, Rabia Alloti, Chahinez Boussahoua, ... Abdeltif Amrane

  Front. Biosci. (Landmark Ed) 2023, 28(10), 264; https://doi.org/10.31083/j.fbl2810264

  Abstract Full Text PDF(6.83MB)

  26

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  150

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• Open Access Original Research

  Comparative Evaluation of Salivary Parameters in Tobacco Substance Abusers

  Rashmi Bhavsar, Vandana Shah, Rahul Bhavasar, Namratha A. Ajith, ... Shilpa Bhandi

  Front. Biosci. (Landmark Ed) 2023, 28(10), 263; https://doi.org/10.31083/j.fbl2810263

  Abstract Full Text PDF(279.60KB)

  38

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  101

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• Open Access Review

  HuR and Its Interactions with Noncoding RNAs in Gut Epithelium Homeostasis and Diseases

  Shweta Sharma, Lan Xiao, Jian-Ying Wang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 262; https://doi.org/10.31083/j.fbl2810262

  (This article belongs to the Special Issue Thinking about RNA-Binding Proteins: Emerging Roles in Human Health and Diseases)

  Abstract Full Text PDF(16.54MB)

  28

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  124

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• Open Access Review

  Ciliated, Mitochondria-Rich Postmitotic Cells are Immune-privileged, and Mimic Immunosuppressive Microenvironment of Tumor-Initiating Stem Cells: From Molecular Anatomy to Molecular Pathway

  Babak Behnam, Hassan Fazilaty, Mobina Ghadyani, Pedram Fadavi, Farzad Taghizadeh-Hesary

  Front. Biosci. (Landmark Ed) 2023, 28(10), 261; https://doi.org/10.31083/j.fbl2810261

  Abstract Full Text PDF(602.84KB)

  24

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  150

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• Open Access Review

  HMGB1 Signaling-Mediated Tumor Immunity in Cancer Progress

  Jinlin Wen, Xinyan Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 260; https://doi.org/10.31083/j.fbl2810260

  Abstract Full Text PDF(1.43MB)

  34

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  106

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• Open Access Original Research

  The Effect of Liraglutide on Lung Cancer and Its Potential Protective Effect on High Glucose-Induced Lung Senescence and Oxidative Damage

  Zhiyan Pu, Yanxia Yang, Shuanghong Qin, Xiaojuan Li, ... Weiyu Chen

  Front. Biosci. (Landmark Ed) 2023, 28(10), 259; https://doi.org/10.31083/j.fbl2810259

  Abstract Full Text PDF(11.14MB)

  14

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  98

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• Open Access Systematic Review

  Alzheimer's Disease; Mechanism, Mutations, and Applications of Nano-Medicine

  Muhammad Maisam, Muhammad Tahir Khan, Madeeha Shahzad Lodhi, Kejie Mou, ... Dongqing Wei

  Front. Biosci. (Landmark Ed) 2023, 28(10), 258; https://doi.org/10.31083/j.fbl2810258

  Abstract Full Text PDF(5.62MB)

  80

  Downloads

  197

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• Open Access Original Research

  LINC01572 is a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma

  Yaolin Zheng, Zhenshan Zhang, Xueyan Li, Leilei Wu, ... Dongping Wei

  Front. Biosci. (Landmark Ed) 2023, 28(10), 257; https://doi.org/10.31083/j.fbl2810257

  (This article belongs to the Special Issue New Targets in Anticancer Therapy)

  Abstract Full Text PDF(7.51MB)

  29

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  128

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• Open Access Review

  The Many Roles of A-to-I RNA Editing in Animals: Functional or Adaptive?

  Dongwu Zhan, Caiqing Zheng, Wanzhi Cai, Hu Li, Yuange Duan

  Front. Biosci. (Landmark Ed) 2023, 28(10), 256; https://doi.org/10.31083/j.fbl2810256

  Abstract Full Text PDF(3.55MB)

  28

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  115

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• Open Access Review

  Secondary Protein Aggregates in Neurodegenerative Diseases: Almost the Rule Rather than the Exception

  Fabio Moda, Arianna Ciullini, Ilaria Linda Dellarole, Annalisa Lombardo, ... Giorgio Giaccone

  Front. Biosci. (Landmark Ed) 2023, 28(10), 255; https://doi.org/10.31083/j.fbl2810255

  (This article belongs to the Special Issue From protein misfolding to dementia: basic research, innovative diagnosis and early biomarkers)

  Abstract Full Text PDF(1.88MB)

  169

  Downloads

  333

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• Open Access Original Research

  Development and Validation of a Prognosis-Prediction Signature for Patients with Lung Adenocarcinoma Based on 11 Telomere-Related Genes

  Jia Liu, Sha Sha, Jian Wang, Xiaowei Gu, ... Xu Lu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 254; https://doi.org/10.31083/j.fbl2810254

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(23.46MB)

  22

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  135

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• Open Access Original Research

  Molecular Subtypes of Ovarian Cancer Based on Lipid Metabolism and Glycolysis Reveals Potential Therapeutic Targets

  Xiangyu Wang, Wenli Xie, Di Zhao, Ming Liu, ... Hao Yu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 253; https://doi.org/10.31083/j.fbl2810253

  Abstract Full Text PDF(10.45MB)

  23

  Downloads

  98

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• Open Access Original Research

  8-Oxoguanine-DNA-Glycosylase Gene Polymorphism and the Effects of an Alternating Magnetic Field on the Sensitivity of Peripheral Blood

  Elena Tekutskaya, Gennady Il’chenko, Anna Dorohova, Vadim Malyshko, ... Stepan Dzhimak

  Front. Biosci. (Landmark Ed) 2023, 28(10), 252; https://doi.org/10.31083/j.fbl2810252

  (This article belongs to the Special Issue Update on Biophysics of Nucleic Acids)

  Abstract Full Text PDF(2.12MB)

  12

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  100

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• Open Access Original Research

  Serum Metabolomic Profile in Hypoxia-Induced Pulmonary Hypertension Mice after C75 Treatment

  Shun Chen, Shujia Lin, Wei Liu, Qiuping Lin, ... Lijian Xie

  Front. Biosci. (Landmark Ed) 2023, 28(10), 251; https://doi.org/10.31083/j.fbl2810251

  (This article belongs to the Special Issue Lipids and lipid metabolism in cardiovascular disease)

  Abstract Full Text PDF(3.89MB)

  18

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  82

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• Open Access Review

  The Role and Application of the AMPK-Sirtuins Network in Cellular Senescence

  Yukun Han, Yifan Liu, Yanhua Zhang, Wei Wang, ... Xiaochun Peng

  Front. Biosci. (Landmark Ed) 2023, 28(10), 250; https://doi.org/10.31083/j.fbl2810250

  Abstract Full Text PDF(2.93MB)

  39

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  138

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• Open Access Original Research

  Rapid Detection and Analysis of Raman Spectra of Bacteria in Multiple Fields of View Based on Image Stitching Technique

  Xiaohui Dou, Fengna Yang, Nan Wang, Ying Xue, ... Bei Li

  Front. Biosci. (Landmark Ed) 2023, 28(10), 249; https://doi.org/10.31083/j.fbl2810249

  (This article belongs to the Special Issue The Biomedical Applications of Raman Spectroscopy)

  Abstract Full Text PDF(7.06MB)

  18

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  130

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• Open Access Review

  A Pharmaceutical Paradigm for Cardiovascular Composite Risk Assessment Using Novel Radiogenomics Risk Predictors in Precision Explainable Artificial Intelligence Framework: Clinical Trial Tool

  Luca Saba, Mahesh Maindarkar, Narendra N. Khanna, Amer M. Johri, ... Jasjit S. Suri

  Front. Biosci. (Landmark Ed) 2023, 28(10), 248; https://doi.org/10.31083/j.fbl2810248

  (This article belongs to the Special Issue Explainable Artificial Intelligence in Biomedicine)

  Abstract Full Text PDF(6.92MB)

  32

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  123

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• Open Access Review

  Discoveries in Retina Physiology and Disease Biology Using Single-Cell RNA Sequencing

  Yuanjuan Zong, Shengyan Xiao, Daoxi Lei, Huili Li

  Front. Biosci. (Landmark Ed) 2023, 28(10), 247; https://doi.org/10.31083/j.fbl2810247

  Abstract Full Text PDF(1.12MB)

  34

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  98

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• Open Access Original Research

  Establishment of Ferroptosis-Associated Molecular Subtypes and Hub Genes Related to the Immune Microenvironment of Heart Failure

  Jiabin Zhou, Jiayu Shi, Peng Xu, Gujie Wu, ... Qi Lu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 246; https://doi.org/10.31083/j.fbl2810246

  Abstract Full Text PDF(14.80MB)

  21

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  118

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• Open Access Review

  Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis

  Arnaud John Kombe Kombe, Samira Zoa-Assoumou, Guy-Armel Bounda, Fleury-Augustin Nsole-Biteghe, ... Abdou Azaque Zouré

  Front. Biosci. (Landmark Ed) 2023, 28(10), 245; https://doi.org/10.31083/j.fbl2810245

  Abstract Full Text PDF(2.98MB)

  73

  Downloads

  170

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• Open Access Original Research

  Comparative Proteomic Analysis of Irradiation-Induced Radioresistant Breast Cancer Cells Using Label-Free Quantitation

  Yingxia Ying, Lei Bian, Yiling Meng, Meichao Zhang, ... Dong Li

  Front. Biosci. (Landmark Ed) 2023, 28(10), 244; https://doi.org/10.31083/j.fbl2810244

  (This article belongs to the Special Issue New Targets in Anticancer Therapy)

  Abstract Full Text PDF(14.77MB)

  24

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  110

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• Open Access Original Research

  Overexpression of PSAT1 is Correlated with Poor Prognosis and Immune Infiltration in Non-Small Cell Lung Cancer

  Hongmu Li, Chun Wu, Wuguang Chang, Leqi Zhong, ... Youfang Chen

  Front. Biosci. (Landmark Ed) 2023, 28(10), 243; https://doi.org/10.31083/j.fbl2810243

  Abstract Full Text PDF(14.32MB)

  30

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  92

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• Open Access Original Research

  Construction and Validation of a Prognostic Model of Metabolism-Related Genes Driven by Somatic Mutation in Bladder Cancer

  Liang Wei, Lina Ji, Shuaihong Han, Mingquan Xu, Xiaofeng Yang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 242; https://doi.org/10.31083/j.fbl2810242

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(12.20MB)

  14

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  99

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• Open Access Original Research

  Multifarious Plant Growth-Promoting Rhizobacterium Enterobacter sp. CM94-Mediated Systemic Tolerance and Growth Promotion of Chickpea (Cicer arietinum L.) under Salinity Stress

  Anjney Sharma, Hillol Chakdar, Anukool Vaishnav, Alok Kumar Srivastava, ... Rajeev Kaushik

  Front. Biosci. (Landmark Ed) 2023, 28(10), 241; https://doi.org/10.31083/j.fbl2810241

  (This article belongs to the Special Issue Molecular Mechanisms of Growth Regulation and Stress Resistance in Plants)

  Abstract Full Text PDF(15.79MB)

  44

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  101

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• Open Access Review

  The Physiopathologic Roles of Calcium Signaling in Podocytes

  Yu-Chi Tu, Hua-Pan Shu, Lu-Lu Sun, Qian-Qian Liao, ... Li-Jun Yao

  Front. Biosci. (Landmark Ed) 2023, 28(10), 240; https://doi.org/10.31083/j.fbl2810240

  Abstract Full Text PDF(3.98MB)

  37

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  139

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• Open Access Original Research

  A Conserved Domain of HCV E2 Glycoprotein Interacts with Human CD81 and Induces Interferon-Gamma Secretion from Peripheral Blood Mononuclear Cells

  Zhiyan Dai, Wei Zeng, Gang Li, Xin Shu

  Front. Biosci. (Landmark Ed) 2023, 28(10), 239; https://doi.org/10.31083/j.fbl2810239

  Abstract Full Text PDF(1.91MB)

  19

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  80

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• Open Access Original Research

  C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension

  Chongjian Wang, Zhiyu Wang, Jing Xu, Hongkun Ma, ... Wen Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 238; https://doi.org/10.31083/j.fbl2810238

  Abstract Full Text PDF(11.23MB)

  35

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  125

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• Open Access Review

  Apigenin’s Therapeutic Potential Against Viral Infection

  In-Gu Lee, Jeonghyeon Lee, So-Hee Hong, Young-Jin Seo

  Front. Biosci. (Landmark Ed) 2023, 28(10), 237; https://doi.org/10.31083/j.fbl2810237

  (This article belongs to the Special Issue Research on Influenza Viruses)

  Abstract Full Text PDF(2.35MB)

  30

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  120

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• Open Access Original Research

  Integrative Transcriptome and Metabolome Analysis to Reveal Red Leaf Coloration in Shiya Tea (Adinandra nitida)

  Runsheng Huang, Yiting Su, Haoye Shen, Wanchuan Liu, ... Bipei Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 236; https://doi.org/10.31083/j.fbl2810236

  Abstract Full Text PDF(8.91MB)

  38

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  132

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• Open Access Original Research

  The Pyroptosis-Related Signature Composed of GSDMC Predicts Prognosis and Contributes to Growth and Metastasis of Hepatocellular Carcinoma

  Min Li, Qiuyu Jiang, Xinyi Liu, Liping Han, ... Ruyi Xue

  Front. Biosci. (Landmark Ed) 2023, 28(10), 235; https://doi.org/10.31083/j.fbl2810235

  (This article belongs to the Special Issue Multi-Omics Biomarker Signatures in Precision Cancer Medicine)

  Abstract Full Text PDF(7.65MB)

  20

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  128

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• Open Access Original Research

  Characterization of DNA Damage Repair Related Signature and Molecular Feature in Low-Grade Gliomas to Aid Chemotherapy and Drug Discovery

  Xin Yin, Min Li, Zheng He

  Front. Biosci. (Landmark Ed) 2023, 28(10), 234; https://doi.org/10.31083/j.fbl2810234

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(14.08MB)

  13

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  112

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• Open Access Original Research

  Assembly and Characterization of the Mitochondrial Genome of Fallopia aubertii (L. Henry) Holub

  Xin Zhang, Yong-Chang Lu, Jiu-Li Wang

  Front. Biosci. (Landmark Ed) 2023, 28(10), 233; https://doi.org/10.31083/j.fbl2810233

  Abstract Full Text PDF(10.50MB)

  64

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  221

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