Multi-Omics Biomarker Signatures in Precision Cancer Medicine

Dear Colleagues,

Most patients have advanced tumors due to late diagnosis and, as a result, survival outcomes remain poor despite advances in treatment and decades of research. To date, oncology has led precision medicine efforts, largely because of our broad understanding of the role of genetic mutations in cancer development and progression. Recent advances in precision medicine techniques have led to unprecedented efforts. Precision cancer medicine depends on the impact of germline and somatic cell differences on the way cancer patients respond to treatment. Currently, precision cancer medicine is in the midst of a multi-omics revolution: improvements in measurement technologies have made it possible for the first time to sequence thousands of exomes/whole genomes, and even to explore entire genomes, transcriptomes, proteomes, and metabolites at the single-cell level. Molecular characterization will help clinicians to provide information relevant to personalized treatment planning through a multifaceted assessment of multi-omics. To realize the potential of therapeutics in clinical applications, it is essential to understand the fundamental aspects of cancer biology. In this special issue, we look to achieve precision in cancer medicine through a multi-omics approach. We encourage submissions that utilize a multi-omics approach to discover new findings or new targets in cancer. We encourage submissions that utilize a multi-omics approach to discover new cancer discoveries or new targets in order to effectively generate, analyze, and interpret multi-omics data to inform decisions based on precision medicine.

- Personalized medicine in oncology
- Cancer biomarkers: screening and diagnosis
- Multi-omics analysis
- Epidemiology

Dr. Chia-Jung Li and Dr. Zhenjian Zhuo

Guest Editors

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.