Proteomic Characterization of Necroptosis-Related Proteins Reveals the Role of Endometrial Dysfunction in Predicting Pregnancy Outcomes in Polycystic Ovary Syndrome

Wenhu Xin, Kexin Wang, Chengbin Tao, Xiuli Tian, Fang Wang

Front. Biosci. (Landmark Ed) 2025, 30(11), 47322; https://doi.org/10.31083/FBL47322 (registering DOI)

Protective Effects of Standardized Peucedanum Japonicum Thunb. Extract Against UVB-Induced Corneal Epithelial Apoptosis via Mitochondrial Regulation

Hye-Sun Lim, Young-Sik Yoo, Gunhyuk Park, Sunoh Kim

Front. Biosci. (Landmark Ed) 2025, 30(11), 46498; https://doi.org/10.31083/FBL46498 (registering DOI)

Sodium Alginate Microgel-Wrapped Primary Human Peritoneal Mesothelial Cells for the Treatment of Peritoneal Fibrosis Caused by Dialysis via the POSTN/NF-κB/CXCL8 Pathway

Shuqing Ma, Chunyan Qiu, Jue Zhang, Luhui Wang, Yaozhe Ying, Ke Zhang, Xiao Yang, Changcan Shi, Yunting Wang, Chenfei Zheng, Zhe Lin, Chaosheng Chen, Yongheng Bai, Yangping Shentu, Chunwu Zhang, Ying Zhou

Front. Biosci. (Landmark Ed) 2025, 30(11), 45614; https://doi.org/10.31083/FBL45614 (registering DOI)

The Fine Structure of the Transcriptome: Does It Reflect the Inverse Symmetry of the Genome?

Gregory Warr, Les Hatton

Front. Biosci. (Landmark Ed) 2025, 30(11), 45912; https://doi.org/10.31083/FBL45912 (registering DOI)

Nanoantioxidants and Their Potential Use in the Management of Oxidative Stress-Associated Male Infertility

Zahra Bakhtiary, Yasaman Eyvazi, Renata Finelli, Saradha Baskaran, Suresh C. Sikka, Manesh Kumar Panner Selvam

Front. Biosci. (Landmark Ed) 2025, 30(11), 39945; https://doi.org/10.31083/FBL39945 (registering DOI)

Impact of Dapagliflozin on Gut Microbiota and Plasma Metabolomic Profiles in Patients With Heart Failure

Ying Zhang, Yan Liu, Qingqing Liu, Qingling Zhang, Wenjing Zhu, Chao Ma, Zhen Zhu, Zhong Fang, Xiaodong Xu

Front. Biosci. (Landmark Ed) 2025, 30(11), 46142; https://doi.org/10.31083/FBL46142 (registering DOI)

Progress and Future Perspectives of Treg Cell Therapy

Kehua Fang, Jinbao Zong, Xiaotian Chang

Front. Biosci. (Landmark Ed) 2025, 30(11), 41250; https://doi.org/10.31083/FBL41250 (registering DOI)

Interrogating the Involvement of Autophagy, Senescence, and the Immune System in the Actions of Sacituzumab Govitecan as an Anticancer Agent

Melanie M. Sinanian, Eesha Chakraborty, Ahmed M. Elshazly, Shady Azzam, Nada Nassif, David A. Gewirtz

Front. Biosci. (Landmark Ed) 2025, 30(11), 39310; https://doi.org/10.31083/FBL39310 (registering DOI)

(This article belongs to the Special Issue New Targets in Anticancer Therapy)

Combined Schisandrin B and Temozolomide Treatment Induces Mitochondrial Apoptosis in Glioma Cells

Zebo Tang, Chaoran Guo, Na Wen, Hong Jin, Yuan Dong, Bo Xu, Xiangyu Ma, Liu Han, Jianxin Liu

Front. Biosci. (Landmark Ed) 2025, 30(11), 46410; https://doi.org/10.31083/FBL46410 (registering DOI)

Overexpression of Suppresses Cell Viability and Enhances the Anti-Cancer Effects of Anti- Therapy in Renal Cell Carcinoma

Yi He, Bo Yang, Ying Ke, Dianlong Zhang, Yiqun Yao

Front. Biosci. (Landmark Ed) 2025, 30(11), 46252; https://doi.org/10.31083/FBL46252 (registering DOI)

Integration of Meta-Analysis and Network Pharmacology to Investigate the Pharmacological Mechanisms of Quercetin on Hepatocellular Carcinoma

Zhiguo Tan, Yu Chen, Yuhuai Peng, You Tang, Bo Sun, Jia Zhou, Yufan Zhou, Ou Li, Chuang Peng, Xu Chen

Front. Biosci. (Landmark Ed) 2025, 30(11), 46289; https://doi.org/10.31083/FBL46289 (registering DOI)

Aldosterone-Induced Renal Lymphangiogenesis and Endothelial–To–Mesenchymal Transformation to Promote Renal Interstitial Fibrosis Through the MR/TGF-β1 Pathway in Mice

Lili Fan, Ziqian Liu, Yi Chang, Yunzhao Xiong, Fan Yang, Xiaomeng Gao, Jingyue Chang, Tatsuo Shimosawa, Qingyou Xu, Panpan Qiang

Front. Biosci. (Landmark Ed) 2025, 30(11), 45591; https://doi.org/10.31083/FBL45591 (registering DOI)

Pericytes in Brain Homeostasis: Developmental Roles and Adult Functions

Uliana Drozd, Svetlana Vechkapova, Dmitriy Lanshakov

Front. Biosci. (Landmark Ed) 2025, 30(11), 42742; https://doi.org/10.31083/FBL42742 (registering DOI)

AAV2/9 Enables Superior Germ Cell Transduction in Mouse Testes

Bangguo Wu, Yadong Guo, Runsheng Li

Front. Biosci. (Landmark Ed) 2025, 30(11), 46354; https://doi.org/10.31083/FBL46354 (registering DOI)

Epirubicin Induces Cell Cycle Arrest in Multiple Myeloma Cells by Downregulating CDC20 Expression

Zhen Nan, Xueting Wang, Yaomei Wang, Yushan Cui, Baijun Fang

Front. Biosci. (Landmark Ed) 2025, 30(11), 46326; https://doi.org/10.31083/FBL46326 (registering DOI)

Ferroptosis in Neurovascular Unit of Ischemic Stroke: Multidimensional Regulatory Mechanisms and Targeted Interventions

Ting Wang, JiaWei Zeng, JingHao Zhang, XiaoXu Sun, Chao Jiang

Front. Biosci. (Landmark Ed) 2025, 30(11), 40737; https://doi.org/10.31083/FBL40737 (registering DOI)

(This article belongs to the Special Issue Regulated Cell Death and Disease)

P110 Inhibits DRP1/FIS1-Mediated Mitochondrial Fission to Alleviate Uric Acid–Induced Apoptosis in HK-2 Cells

Yuli Shen, Geng Huang, Yu Liu, Fulin Pan, Canling Long, Jia Liu, Zhigang Ma

Front. Biosci. (Landmark Ed) 2025, 30(11), 46700; https://doi.org/10.31083/FBL46700 (registering DOI)

(This article belongs to the Special Issue Mitochondria Targeting Strategies for Treatment of Human Diseases)

AI-Driven Structural Elucidation of the Bacteriophage KP32: Decoding Its Molecular Arsenal Against

Mario Privitera, Giovanni Barra, Flavia Squeglia, Zuzanna Drulis-Kawa, Valeria Napolitano, Rita Berisio

Front. Biosci. (Landmark Ed) 2025, 30(11), 46489; https://doi.org/10.31083/FBL46489 (registering DOI)

Microbiome Modulation in Lung Cancer Immunotherapy: Unveiling the Role of Respiratory and Gut Microbiota in the PD-1/PD-L1 Response

Yuanyuan Xu, Yixing Tao, Hanbo Pan, Zhongjie Wang, Hui Wang, Qingquan Luo

Front. Biosci. (Landmark Ed) 2025, 30(11), 41531; https://doi.org/10.31083/FBL41531 (registering DOI)

Comprehensive Analysis of the ADCY Family and Identification of ADCY5 as a Prognostic Marker for Gastric Cancer

Yuzhe Zhang, Lirong Yan, Yanke Li, Ye Zhang

Front. Biosci. (Landmark Ed) 2025, 30(11), 45527; https://doi.org/10.31083/FBL45527 (registering DOI)

The Single-Cell Atlas Reveals Subset-Specific Transcriptional Programs of NK Cells in Skin Inflammation

Jiazheng Sun, Yilun Wang, Lanmei Lin, Xinyi Zhu, Xiaonian Lu, Junhao Zhu, Canbin Dong, Juan Du

Front. Biosci. (Landmark Ed) 2025, 30(11), 47056; https://doi.org/10.31083/FBL47056 (registering DOI)

Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response

Mingjin Li, Zhenhong Wei, Xiaohong Chen, Huifang Wu, Xue Han, Yaping Pei, Jiyu Chen, Shouye Ma

Front. Biosci. (Landmark Ed) 2025, 30(11), 45744; https://doi.org/10.31083/FBL45744 (registering DOI)

HMGA1/SMAD3 Promoter Complex Mediates PD-L1-Dependent Transcriptional Regulation of GAS6, EGR1 and PD-L1

Hui Guo, Wei Liu, Pingping Tan

Front. Biosci. (Landmark Ed) 2025, 30(11), 46743; https://doi.org/10.31083/FBL46743 (registering DOI)

L. Leaf and Pseudostem Extract Suppresses Inflammation in Cytokine-Stimulated HaCaT Keratinocytes and 12-O-Tetradecanoylphorbol-13-Acetate-Induced Ear Edema in Mice

Arachchige Maheshika Kumari Jayasinghe, Kirinde Gedara Isuru Sandanuwan Kirindage, Kyungsook Jung, Jihye Lee, Seok Lee, Hitihami Mudiyanselage Chalani Bhagya Deshapriya, Hewayalage Madushika Kumari Ranasinghe, Lei Wang, Ji Soo Kim, Ginnae Ahn

Front. Biosci. (Landmark Ed) 2025, 30(11), 42888; https://doi.org/10.31083/FBL42888 (registering DOI)

Histone Modification Networks Reshape the Metabolism and Treatment Landscape of Urological Cancers

Fengye Liu, Longfei He, Muying Yu, Junyi Chen, Yuxiao Huang, Wenzhe Ma, Ying Wan, Bingru Zhou

Front. Biosci. (Landmark Ed) 2025, 30(11), 42831; https://doi.org/10.31083/FBL42831 (registering DOI)

Macrophage–Fibroblast Crosstalk in Fibrosis: Key Regulator of Fibrosis Across Different Organs

Ruofan Su, Licheng Song, Yaru Liu, Chunyang Zhang, Lixin Xie, Zhihai Han

Front. Biosci. (Landmark Ed) 2025, 30(11), 38864; https://doi.org/10.31083/FBL38864 (registering DOI)

Macrophages and Tissue Homeostasis: From Physiological Functions to Disease Onset

Yehua Li, Huanhuan Chen, Shen’ao Zhou

Front. Biosci. (Landmark Ed) 2025, 30(11), 42706; https://doi.org/10.31083/FBL42706 (registering DOI)

Advances in the Study of Intestinal Microbiota and Neuropathic Pain

Yuxin Jiang, Huizhe Xu, Wenshun Zhang, Shengbo Jin, Haozhe Piao, Jun Yu, Huini Yao, Jie Shi, Qian Liu, Ningxin Li, Yue Shen, Jiaqing Fu, Mingzhu Li

Front. Biosci. (Landmark Ed) 2025, 30(11), 43051; https://doi.org/10.31083/FBL43051 (registering DOI)

Targeting Akt Signaling Pathway in Cancer: Molecular Mechanisms and Advances in Therapeutic Interventions

Premila D. Leiphrakpam, Rishi Batra, Laura Tenner, Chandrakanth Are

Front. Biosci. (Landmark Ed) 2025, 30(11), 39100; https://doi.org/10.31083/FBL39100 (registering DOI)

Therapeutic Potential of CLDN Family Proteins in Ovarian Cancer: Emerging Biomarkers and Targets

Yu Wu, Zhitong Bing, Yongxiu Yang, Kehu Yang

Front. Biosci. (Landmark Ed) 2025, 30(11), 45244; https://doi.org/10.31083/FBL45244 (registering DOI)