Special Issues

• From protein misfolding to dementia: basic research, innovative diagnosis and early biomarkers

  Guest Editors: Fabio Moda, Giorgio Giaccone
  Keywords: Diagnostics; Nervous System; Molecular Biology
  (4 Papers published)
  Submission deadline: 30 September 2023

• 60 Years Following F. Ritossa's Discovery of Heat Stress Response: Novel Advances in Exploring and Exploiting Heat Shock Proteins

  Guest Editor: Alexander E. Kabakov
  Keywords: heat shock protein; heat shock factor-1; molecular chaperone; biomedicine; biotechnology
  (1 Paper published)
  Submission deadline: 30 September 2023

• Nuclear Receptors in Metabolism and Cancer: from Molecular Mechanisms to Therapeutic

  Guest Editors: Elena Piccinin, Raffaella M Gadaleta, Marica Cariello
  Keywords: nuclear receptors; metabolism; cancer; molecular mechanism; therapy
  Submission deadline: 30 September 2023

• Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders

  Guest Editors: Masaru Tanaka, Simone Battaglia
  Keywords: neurological diseases; psychiatric disorders; non-invasive brain stimulation; altered cognitive processes; neurocognitive disorders; neurodegenerative disorders; cognitive, behavioral, and functional disorders
  (3 Papers published)
  Submission deadline: 30 September 2023

• New Insights into Computational Medicine and Bioinformatics Research

  Guest Editor: Balachandran Manavalan
  Keywords: bioinformatics; computational biology; sequence/structure analysis; feature optimization; ensemble learning
  Submission deadline: 30 September 2023

• Cardiovascular Imaging: New Technologies, Innovative Applications, and Novel Image Processing Strategies

  Guest Editors: Paolo Zaffino, Maria Francesca Spadea, Salvatore De Rosa, Isabella Leo
  Keywords: cardiovascular imaging; medical imaging; medical image processing; X-ray; echocardiography; cardiovascular magnetic resonance; computed tomography; nuclear imaging; intravascular imaging
  Submission deadline: 30 September 2023

• New Insights into the Analysis of Natural Products

  Guest Editor: Nour-Eddine ES-SAFI
  Keywords: natural products; analysis; structure; extraction; isolation; characterization; chromatography; spectroscopy
  Submission deadline: 30 September 2023

• New Insights into Resveratrol Associated with Longevity

  Guest Editors: Roberto Bei, Chiara Focaccetti
  Keywords: resveratrol; ageing; tumor microenvironment; immune cells; metabolism; inflammation
  Submission deadline: 30 September 2023

• Mechanisms of Protection and/or Therapy for Ischemia and Reperfusion Injury in the Brain, Spinal Cord, Heart, Liver, and Kidney

  Guest Editor: Moo-Ho Won
  Keywords: vital organs; organ dysfunction; oxidative stress; inflammation; excitotoxicity; protection; therapy
  Submission deadline: 30 September 2023

• Neurodegenerative Disorders and Neuroprotective Agents

  Guest Editors: Emanuel Vamanu, Sandeep Kumar Singh
  Keywords: Neurodegenerative diseases; Parkinson’s disease; amyloidosis; drug discovery; drug delivery; nanotechnology; natural compounds; drug development; therapeutic biomarker; theranostics; microbiota; modulation processes
  Submission deadline: 10 October 2023

• Molecular Mechanisms in Anxiety and Depression

  Guest Editor: Giovanna Traina
  Keywords: depression; anxiety; stress; molecular mechanisms; neuroinflammation; microglia; mast cells; synaptic plasticity
  Submission deadline: 15 October 2023

• Bone Marrow Edema

  Guest Editors: GIANANTONIO SAVIOLA, Luigi Molfetta
  Keywords: bone marrow edema; bisphosphonates; CRPS-1; bone marrow edema syndromes
  Submission deadline: 20 October 2023

• Fetal Programming and Epigenetics

  Guest Editor: Ravi Goyal
  Submission deadline: 20 October 2023

• Magnetic Nanoparticles as Efficient Vectors for Drug and Gene Delivery, Catalysis and MR Imaging

  Guest Editor: Cezar Comanescu
  Keywords: magnetic nanoparticles; nanomedicine; drug delivery; hyperthermia; MRI
  Submission deadline: 25 October 2023

• Role of Drosophila in Human Disease Research

  Guest Editors: Silvia Bongiorni, Francesca Cipressa
  Keywords: drosophila melanogaster; human disease model; neurodegenerative diseases; cancer; mitochondrial disorder
  (1 Paper published)
  Submission deadline: 30 October 2023

• Explainable Artificial Intelligence in Biomedicine

  Guest Editor: Nguyen Quoc Khanh Le
  Keywords: big data; bioinformatics; biomedical informatics; clinical decision support system; disease diagnosis; drug discovery; explainable artificial intelligence; genomics; machine learning; medical imaging
  Submission deadline: 30 October 2023

• Plant Bioactive Molecules

  Guest Editors: Paola Bontempo, Daniela Rigano, Luigi De Masi
  Keywords: Bioactive molecules; Biological activity; Food plants; Human diet; Human health; Medicinal plants; Molecular mechanisms; Natural products; Plant Secondary Metabolites
  (4 Papers published)
  Submission deadline: 31 October 2023

• Cross Regulation in Cancer Metastasis

  Guest Editors: Shi-Yong Sun, Yong Teng
  Keywords: cancer; progression; metastasis; tumor micro-environment
  Submission deadline: 31 October 2023

• Endophytic Bacteria: Microbial Ecology, Genomic Analysis and Biotechnological Applications

  Guest Editors: Renato Fani, Giovanni Emiliani, Giulia Semenzato
  Keywords: endophytes; genome; metabolic pathways; bioactive molecules, biotechnology
  Submission deadline: 31 October 2023

• Advances in the Management of Pulmonary and Extrapulmonary Tuberculosis

  Guest Editor: Vishwanath Venketaraman
  Keywords: tuberculosis; host-immune responses; pathogenesis; prevention; novel therapies
  Submission deadline: 31 October 2023

• Update on Macrophages/Microglia in Non-infectious Diseases

  Guest Editors: Andrey Vladimirovich Elchaninov, Giuseppe Caruso
  Keywords: macrophages; microglia; reparation; organ homeostasis; non-infectious diseases; tumor-associated macrophages; oxidative stress; inflammation; drugs; nutraceuticals
  Submission deadline: 31 October 2023

• Molecular, Cellular and Clinical Advances in Periodontal and Peri-Implant Health and Disease

  Guest Editor: Gustavo Vicentis De Oliveira Fernandes
  Keywords: molecular; cytokines; cell behavior; clinical approach; periodontal diseases; periodontitis; peri-implant diseases; peri-implantitis; microorganisms; disbiose
  Submission deadline: 31 October 2023

• Advances in Bioimaging

  Guest Editor: Elahe Alizadeh
  Keywords: small-animal models; in vivo; ex vivo; multimodality imaging; contrast agents; cardiopulmonary; computed tomography; high-resolution imaging; biomarkers; optical imaging
  Submission deadline: 31 October 2023

• Traumatic Brain Injury: Cellular and Molecular Response

  Guest Editors: Brandon P. Lucke-Wold, Deepak Lakshmipathy
  Keywords: traumatic brain injury; hemodynamic stability; recovery genetics; neurosurgical management; neurological deficit
  Submission deadline: 10 November 2023

• Molecular Pharmacology of Melatonin Receptors: From Signal Integration to Disease Mechanisms and Aging

  Guest Editor: Yung Hou Wong
  Keywords: melatonin; G protein-coupled receptor; signaling; disease mechanism; aging
  Submission deadline: 20 November 2023

• Thinking about RNA-Binding Proteins: Emerging Roles in Human Health and Diseases

  Guest Editor: Christian Barbato
  Keywords: RNA-binding proteins; RNA structure; RNA-protein complex; RNA biomarkers; non-coding RNA; RNA interactions
  (1 Paper published)
  Submission deadline: 30 November 2023

• The Role of Phosphodiesterases in Health and Diseases

  Guest Editor: Federica Campolo
  Keywords: phosphodiesterases; cGMP/cAMP; PKG/PKA; PDE Inhibitors
  (1 Paper published)
  Submission deadline: 30 November 2023

• Influence of Radiation Quality on Cellular, Molecular and Inflammatory Responses in Normal and Malignant Human Cells

  Guest Editor: Isabelle Testard
  Keywords: radiobiology; cancer radiotherapy; space radiation protection; normal and cancer human cells; ionizing radiation; high-LET radiation; DNA damage responses; inflammatory responses; bystander effects; microdosimetry and simulation
  Submission deadline: 30 November 2023

• New Insights into the Quality of Sperm Cells

  Guest Editor: Eva Tvrda
  Keywords: sperm physiology; sperm pathophysiology; risk factors; molecular regulation; management of infertility
  (1 Paper published)
  Submission deadline: 30 November 2023

• An Update on the Glucocorticoid Receptor

  Guest Editors: Elena A. Rybnikova, Oleg Vetrovoy
  Keywords: corticosteroids; glucocorticoid receptors; post-translational modifications; cell signaling; gene expression
  Submission deadline: 30 November 2023

• RNAi Applications in Gene Regulation and in Protection against Insect Pests and Pathogens in Plants

  Guest Editors: Kristof De Schutter, Francesca Negrini, Zeraye Mehari Haile
  Keywords: RNA interference; double strand RNA; spray-induced gene silencing (SIGS); host-induced gene silencing (HIGS); viral-induced gene silencing (VIGS)
  Submission deadline: 30 November 2023

• Cellular and Molecular Mechanisms of Anticancer Compounds

  Guest Editor: Giovanni Ribaudo
  Keywords: medicinal chemistry; drug discovery; drug repurposing; molecular modeling; mechanistic studies; natural compounds
  (1 Paper published)
  Submission deadline: 30 November 2023

• Fermented Foods: Characterization of Autochthonous Microbiota Using OMIC Methodologies

  Guest Editor: Teresa Semedo-Lemsaddek
  Keywords: fermented foods; autochthonous microbiota; foodborne pathogens; antimicrobial drug resistance; virulence; zoonoses; food safety
  Submission deadline: 30 November 2023

• Dynamic Diseases: Mathematical Informed Expert and Knowledge Computing Technology-based Computational Medicine in Complex Systems

  Guest Editors: Yeliz Karaca, Dumitru Baleanu, Yu-Dong Zhang, Majaz Moonis, Osvaldo Gervasi, Khan Muhammad
  Keywords: Dynamic diseases; Computational medicine; Mathematics-Informed medicine; Algorithmic computation; Data analytics-based models; Dynamic precision medicine; AI for healthcare
  (2 Papers published)
  Submission deadline: 01 December 2023

• The Contribution of Mitochondria to Aging

  Guest Editor: Anna Picca
  Keywords: age-related conditions; autophagy; extracellular vesicles; mitochondrial DNA; omics
  Submission deadline: 20 December 2023

• Innovations in Endodontics and Adhesive Dentistry: From Root Canal Treatments to Adhesive Rehabilitation

  Guest Editors: Alessio Zanza, Luca Testarelli, Rodolfo Reda
  Keywords: endodontics; adhesive dentistry; nickel-titanium rotary instruments; adhesive; composite; sealers; irrigation; mechanical stress; restorative dentistry; dental imaging; diagnosis; molecular biology; cytotoxicity; stem cell; inflammation pathways
  Submission deadline: 20 December 2023

• Cellular and Molecular Mechanisms of Metabolic Liver Disease-associated Hepatocellular Carcinoma

  Guest Editor: Ming Yang
  Keywords: hepatocellular carcinoma; metabolic liver disease; cellular and molecular mechanisms; cancer therapy; basic studies
  Submission deadline: 20 December 2023

• Vascular Mechanisms in Skeletal Disease

  Guest Editor: Roy K. Aaron
  Submission deadline: 20 December 2023

• Co-evolution of genome and mobilome

  Guest Editors: Chengyi Song, Mikhail Puzakov
  Keywords: Mobilome; Genome; Transposon; Retrotransposon; Transposable Element; Domestication; Exaptation; Horizontal Transfer
  Submission deadline: 30 December 2023

• Atrial Fibrillation, from Pathophysiology to Early Detection and Therapeutic Approaches

  Guest Editor: Martin Ezeani
  Keywords: Cardiac; Arrhythmias; Atrial Fibrillation
  Submission deadline: 30 December 2023

• Metallic and Polymeric Nanoparticles for Drug Research and Biomedical Applications

  Guest Editors: Jaison Jeevanandam, Satheesh Kumar Balu
  Keywords: nanoparticles; nanoformulations; drug research; nanocarriers; pharmaceutics
  Submission deadline: 30 December 2023

• Application of novel diagnosis and treatment technologies in precision oncology

  Guest Editors: Xiaofang Che, Jia Wang, Chunlei Zheng
  Keywords: Cancer; Precision Medicine; Biomarker; Artificial Intelligence (AI); Liquid Biopsy; New Therapy Strategy
  Submission deadline: 31 December 2023

• Gut microbiota metabolites in human health and disease

  Guest Editor: Robert A. Olek
  Keywords: Trimethylamine N-oxide; Trimethylamine; Carnitine; Choline; Betaine; Nitrite; Nitrate; Oxidative stress; Inflammation
  Submission deadline: 31 December 2023

• Calcium dyshomeostasis in disease and therapy

  Guest Editors: Peng Zhang, Xianhai Zeng
  Keywords: Calcium Channels; Calcium Signaling; Disease; Therapy; Ionotropic Receptors
  Submission deadline: 31 December 2023

• Healthy Culture of aquatic animals

  Guest Editors: Xiaohong Tan, Zhenzhu Sun
  Keywords: Nutrition and Immunity of Aquatic Animals; Functional Feed Additives for Aquatic Feed; Fish Meal and Fish Oil Substitution; Regulation and Treatment of Aquaculture Water
  Submission deadline: 31 December 2023

• Bio-effects, molecular mechanisms and exposure paths of emerging contaminants on species in marine aquaculture

  Guest Editors: Jiji Li, Yingying Ye
  Keywords: Marine Animals Health; Contaminants Toxicity; Molecular Mechanisms; Signal Path
  Submission deadline: 31 December 2023

• Application of toxicogenomics in toxicity assessment of food, cosmetics, and dietary supplements

  Guest Editor: Xiugong Gao
  Keywords: Cell Biology
  Submission deadline: 31 December 2023

• Bioactive Compounds from Marine and Terrestrial Organisms

  Guest Editors: Lei Wang, Caoxing Huang
  Keywords: Bioactive Natural Product; Bioprocessing; Human Health; Pharmaceutical; Nutraceutical; Cosmeceutical; Herbal Medicine; Seaweed; Bamboo and Straw
  (1 Paper published)
  Submission deadline: 31 December 2023

• Advances in p53 Signaling and Cancer

  Guest Editor: Maria Lina Tornesello
  Keywords: TP53; p53; oncosuppressor; oncogene; mutation; apoptosis; cancer therapy
  (1 Paper published)
  Submission deadline: 31 December 2023

• The Role of Matrix Metalloproteinases in Human Diseases

  Guest Editor: Raffaele Serra
  Keywords: MMPs; ADAM; ADAMTS; ECM; cardiovascular disease; cancer; chronic wounds; inflammatory disorders; chronic disease
  Submission deadline: 31 December 2023