Volume 28 Issue 12 2023

• Open Access Notice of Withdrawal

  Notice of Withdrawal

  FBL Editorial Office

  Front. Biosci. (Landmark Ed) 2023, 28(12), 369; https://doi.org/10.31083/j.fbl2812369

  Abstract PDF(138.55KB)

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• Open Access Original Research

  RIPK4 Promotes Cell Invasion and the Epithelial–Mesenchymal Transition in Ovarian Cancer

  Li Hua, Jian-Hai Wu, Jing-Ying Xu, San-Gang Wu, Juan Zhou

  Front. Biosci. (Landmark Ed) 2023, 28(12), 368; https://doi.org/10.31083/j.fbl2812368

  Abstract Full Text PDF(5.97MB)

  42

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  204

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• Open Access Original Research

  Canthaxanthin Attenuates the Vascular Aging or Endothelial Cell Senescence by Inhibiting Inflammation and Oxidative Stress in Mice

  Zhefeng Wang, Lilin Li, Souqi Liao, Ren Huang, ... Keda Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 367; https://doi.org/10.31083/j.fbl2812367

  Abstract Full Text PDF(7.13MB)

  48

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  193

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• Open Access Original Research

  Plant-Derived Extracts Plus Vitamin E and/or Aloe Vera Protect Against Intrinsic/Extrinsic Stressor in Human Skin: In Vitro and Clinical Evidence

  Ganesh Diwakar, Lisa Barnes, Melanie Riggs, Helen Knaggs, Zoe Diana Draelos

  Front. Biosci. (Landmark Ed) 2023, 28(12), 366; https://doi.org/10.31083/j.fbl2812366

  Abstract Full Text PDF(2.27MB)

  47

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• Open Access Original Research

  Transcriptome and Pathway Analysis Reveals that Adipose-derived Stem Cells Target Inflammatory Factors and Delay the Progression of Diabetic Liver Disease

  Yanli Hou, Guoliang Gao, Wenyu Ding, Peishan Wu, ... Xiaolei Wang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 365; https://doi.org/10.31083/j.fbl2812365

  (This article belongs to the Special Issue Research Trend of the Inflammasome Regulation)

  Abstract Full Text PDF(12.53MB)

  34

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  107

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• Open Access Review

  Gene Silencing and Gene Delivery in Therapeutics: Insights Using Quantum Dots

  Shrodha Mondal, Jiko Raut, Prithidipa Sahoo

  Front. Biosci. (Landmark Ed) 2023, 28(12), 364; https://doi.org/10.31083/j.fbl2812364

  Abstract Full Text PDF(19.86MB)

  73

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  143

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• Open Access Review

  Biological Immune Mechanism of Retina

  Xingyu Zhu, Jiaxu Hong, Xujiao Zhou

  Front. Biosci. (Landmark Ed) 2023, 28(12), 363; https://doi.org/10.31083/j.fbl2812363

  (This article belongs to the Special Issue Retinal Biology in Health and Disease)

  Abstract Full Text PDF(229.27KB)

  74

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  202

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• Open Access Review

  Cancer Stem Cell Biomarkers in the Nervous System

  Xinyi Li, Jiaqiang Huang, Yulin Kang, Xiyu Cheng, ... Hanli Xu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 362; https://doi.org/10.31083/j.fbl2812362

  Abstract Full Text PDF(5.35MB)

  81

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  163

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• Open Access Review

  An Update on Gemcitabine-Based Chemosensitization Strategies in Pancreatic Ductal Adenocarcinoma

  Tianpeng Zhang, Zongting Gu, Ran Ni, Xiao Wang, ... Ran Tao

  Front. Biosci. (Landmark Ed) 2023, 28(12), 361; https://doi.org/10.31083/j.fbl2812361

  (This article belongs to the Special Issue New Targets in Anticancer Therapy)

  Abstract Full Text PDF(1.11MB)

  24

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• Open Access Original Research

  Bioinformatic Analysis and Computer-Aided Study to Investigate the Potential Application of a Bioflavonoid Compound Bilobetin in Liver Cancer Treatment

  Chunye Zhang, Yuxiang Sui, Shuai Liu, Ming Yang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 360; https://doi.org/10.31083/j.fbl2812360

  Abstract Full Text PDF(10.02MB)

  389

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  1169

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• Open Access Review

  Stem Cell Therapy for Liver Diseases: Current Perspectives

  Jing Wang, Qun Li, Wenbo Li, Nahum Méndez-Sánchez, ... Xingshun Qi

  Front. Biosci. (Landmark Ed) 2023, 28(12), 359; https://doi.org/10.31083/j.fbl2812359

  Abstract Full Text PDF(813.35KB)

  55

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• Open Access Original Research

  Clinical Assessment of Cytokine Profiles and Haematological Parameters in Patients with Systemic Lupus Erythematosus: A Cross-Sectional Study from Saudi Arabia

  Fahad M. Aldakheel, Muwaffaq A. Alshanqiti, Shatha A. Alduraywish, Amal F. Alshammary, ... Rabbani Syed

  Front. Biosci. (Landmark Ed) 2023, 28(12), 358; https://doi.org/10.31083/j.fbl2812358

  (This article belongs to the Special Issue Cytokines in Health and Disease)

  Abstract Full Text PDF(247.04KB)

  22

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  99

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• Open Access Review

  Cellular Senescence in Non-Small Cell Lung Cancer

  Huangkai Zhu, Jiaen Sun, Chong Zhang, Pei Li, ... Guofang Zhao

  Front. Biosci. (Landmark Ed) 2023, 28(12), 357; https://doi.org/10.31083/j.fbl2812357

  Abstract Full Text PDF(256.92KB)

  76

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  191

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• Open Access Review

  Inflammation and Late-Life Depression: Unraveling the Complex Relationship and Potential Therapeutic Strategies

  Jian Xia, Meiling Chen, Heng Shao, Hui Chen, ... Shaoyuan Wu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 356; https://doi.org/10.31083/j.fbl2812356

  Abstract Full Text PDF(565.45KB)

  70

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  185

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• Open Access Review

  A More Holistic Perspective of Alzheimer's Disease: Roles of Gut Microbiome, Adipocytes, HPA Axis, Melatonergic Pathway and Astrocyte Mitochondria in the Emergence of Autoimmunity

  George Anderson

  Front. Biosci. (Landmark Ed) 2023, 28(12), 355; https://doi.org/10.31083/j.fbl2812355

  (This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

  Abstract Full Text PDF(1.53MB)

  140

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  273

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• Open Access Original Research

  Effects of Purine Metabolism-Related LINC01671 on Tumor Heterogeneity in Kidney Renal Clear Cell Carcinoma

  Wei Yin, Jin-Hua Wang, Yu-Mei Liang, Kang-Han Liu, ... Yu-Sa Chen

  Front. Biosci. (Landmark Ed) 2023, 28(12), 354; https://doi.org/10.31083/j.fbl2812354

  Abstract Full Text PDF(11.34MB)

  29

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  159

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• Open Access Original Research

  Assessment of Phenolic Composition, Antioxidant Potential, Antimicrobial Properties, and Antidiabetic Activity in Extracts Obtained from Schinus molle L. Leaves and Fruits

  Selen İlgün, Gökçe Şeker Karatoprak, Derya Çiçek Polat, Esra Köngül Şafak, ... Esra Küpeli Akkol

  Front. Biosci. (Landmark Ed) 2023, 28(12), 353; https://doi.org/10.31083/j.fbl2812353

  (This article belongs to the Special Issue Plant Bioactive Molecules)

  Abstract Full Text PDF(1013.66KB)

  67

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  141

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• Open Access Original Research

  Sequence Analysis of the Plastomes of Two Tibetan Medicinal Plants of the Family Papaveraceae

  Danyang Wu, Qian Qin, Xiaoyun Wang, Yiming Niu, ... Zejing Mu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 352; https://doi.org/10.31083/j.fbl2812352

  Abstract Full Text PDF(4.31MB)

  12

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  83

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• Open Access Review

  FGF21: A Sharp Weapon in the Process of Exercise to Improve NAFLD

  Zhiyuan Wang, Tingting Sun, Jingjing Yu, Siyu Li, ... Yimin Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 351; https://doi.org/10.31083/j.fbl2812351

  Abstract Full Text PDF(3.38MB)

  121

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  201

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• Open Access Review

  The Role of Nucleoporins in Cardiac Tissue Development and Disease

  Xiaocong Chen, Rui Shi, Yu Luo, Liang Xu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 350; https://doi.org/10.31083/j.fbl2812350

  Abstract Full Text PDF(1.01MB)

  25

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• Open Access Original Research

  Unlocking the Potential: Synergistic Effects of Solid SNEDDS and Lyophilized Solid Dispersion to Enhance Stability Attributes

  Ahmad Yousef Tashish, Ahmad Abdul-Wahhab Shahba, Fars Kaed Alanazi, Mohsin Kazi

  Front. Biosci. (Landmark Ed) 2023, 28(12), 349; https://doi.org/10.31083/j.fbl2812349

  (This article belongs to the Special Issue Recent Developments in Drug Delivery)

  Abstract Full Text PDF(4.24MB)

  31

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  77

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• Open Access Review

  Fatty Acid Metabolism: A New Perspective in Breast Cancer Precision Therapy

  Mengye He, Suzhen Xu, Feifei Yan, Jian Ruan, Xiaochen Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 348; https://doi.org/10.31083/j.fbl2812348

  Abstract Full Text PDF(1.09MB)

  81

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  181

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• Open Access Original Research

  GluN2A Mediates PS-Induced Depressive-Like Behavior by Activating CaMKII and Inhibiting Myelinization

  Huimei Huang, Hongli Jiang, Hongli Sun

  Front. Biosci. (Landmark Ed) 2023, 28(12), 347; https://doi.org/10.31083/j.fbl2812347

  Abstract Full Text PDF(19.78MB)

  41

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  92

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• Open Access Original Research

  im5C-DSCGA: A Proposed Hybrid Framework Based on Improved DenseNet and Attention Mechanisms for Identifying 5-methylcytosine Sites in Human RNA

  Jianhua Jia, Lulu Qin, Rufeng Lei

  Front. Biosci. (Landmark Ed) 2023, 28(12), 346; https://doi.org/10.31083/j.fbl2812346

  Abstract Full Text PDF(11.55MB)

  29

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  70

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• Open Access Original Research

  Metabolite Profiling and Comparative Metabolomics Analysis of Jiaozhou Chinese Cabbage (Brassica rapa L. ssp. pekinensis) Planted in Different Areas

  Jingjuan Li, Minghui Qiu, Faujiah Nurhasanah Ritonga, Fengde Wang, ... Jianwei Gao

  Front. Biosci. (Landmark Ed) 2023, 28(12), 345; https://doi.org/10.31083/j.fbl2812345

  Abstract Full Text PDF(1.44MB)

  27

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  103

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• Open Access Original Research

  ATF4 Responds to Metabolic Stress in Drosophila

  Soonhyuck Ok, Jung-Eun Park, Seunghee Byun, Kwonyoon Kang, ... Min-Ji Kang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 344; https://doi.org/10.31083/j.fbl2812344

  Abstract Full Text PDF(5.91MB)

  51

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  200

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• Open Access Original Research

  Identification of Biomarker IL2Rβ in Ankylosing Spondylitis via Multi-Chip Integration Analysis of Gene Differential Expression

  Bin Xiao, Peng-Lei Cui, Hong-Chao Li, Chao Wang, ... Cheng-Ai Wu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 343; https://doi.org/10.31083/j.fbl2812343

  Abstract Full Text PDF(4.63MB)

  29

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  126

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• Open Access Original Research

  DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice

  Linqiao Li, Feixiang Ling, Rou Li, Yan Jiang, ... Libing Ma

  Front. Biosci. (Landmark Ed) 2023, 28(12), 342; https://doi.org/10.31083/j.fbl2812342

  Abstract Full Text PDF(8.83MB)

  40

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  144

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• Open Access Original Research

  Exploration of the Pharmacological Mechanism of Vitexicarpin against Triple-Negative Breast Cancer in Network Pharmacology

  Tianhui Wu, Min Xiang, Yujiao Li, Yahan Gao, ... Yuanshuai Zhou

  Front. Biosci. (Landmark Ed) 2023, 28(12), 341; https://doi.org/10.31083/j.fbl2812341

  Abstract Full Text PDF(5.94MB)

  46

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  109

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• Open Access Original Research

  An Insight into Biochemical Characterization and Explorations of Antioxidant, Antibacterial, Cytotoxic, and Antidiabetic Activities by Trachyspermum ammi Nanosuspensions

  Rizwana Jabeen, Tayyab Ali, Muhammad Naeem, Fatma Hussain, ... Mohammad Javed Ansari

  Front. Biosci. (Landmark Ed) 2023, 28(12), 340; https://doi.org/10.31083/j.fbl2812340

  Abstract Full Text PDF(9.83MB)

  33

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  164

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• Open Access Original Research

  Transcriptome-Wide Dynamics of m7G-Related LncRNAs during the Progression from HBV Infection to Hepatocellular Carcinoma

  Min Shi, Shunshun Zhu, Linying Sun, Jieli Hu, ... Tao Guo

  Front. Biosci. (Landmark Ed) 2023, 28(12), 339; https://doi.org/10.31083/j.fbl2812339

  Abstract Full Text PDF(7.00MB)

  36

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  176

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• Open Access Original Research

  High MEIS3 Expression Indicates a Poor Prognosis for Patients with Stage II/III Colorectal Cancer

  Jian Ma, Haitao Li, Qianqian Gao, Weixing Zhang, ... Ziyan Li

  Front. Biosci. (Landmark Ed) 2023, 28(12), 338; https://doi.org/10.31083/j.fbl2812338

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(3.53MB)

  35

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  161

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• Open Access Original Research

  A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis

  Xiaorong Liu, Shuofu Li, Yin Xu, Wenya Mei, Ribao Zhou

  Front. Biosci. (Landmark Ed) 2023, 28(12), 337; https://doi.org/10.31083/j.fbl2812337

  Abstract Full Text PDF(27.47MB)

  61

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  149

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• Open Access Original Research

  Genotypic Characterization of a Chinese Family with Osteogenesis Imperfecta and Generation of Disease-Specific Induced Pluripotent Stem Cells

  Dandan Li, Minglin Ou, Guandong Dai, Peng Zhu, ... Yong Dai

  Front. Biosci. (Landmark Ed) 2023, 28(12), 336; https://doi.org/10.31083/j.fbl2812336

  Abstract Full Text PDF(3.67MB)

  52

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  170

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• Open Access Original Research

  Influence of Age, Heart Failure and ACE Inhibitor Treatment on Plasma Renin Activity in Children: Insights from a Systematic Review and the European LENA Project

  Melina Steichert, Willi Cawello, Milica Bajcetic, Johannes M.P.J. Breur, ... on behalf of the LENA Consortium

  Front. Biosci. (Landmark Ed) 2023, 28(12), 335; https://doi.org/10.31083/j.fbl2812335

  Abstract Full Text PDF(4.06MB)

  61

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  201

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• Open Access Original Research

  Pyroptosis-Related Subtypes Predict the Response of Clear Cell Renal Cell Carcinoma to Targeted Therapy

  Jinpeng Ma, Zhijian Kang, Guang Yang, Xinyue Wang, ... Wanhai Xu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 334; https://doi.org/10.31083/j.fbl2812334

  Abstract Full Text PDF(10.59MB)

  55

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  217

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• Open Access Original Research

  A Machine Learning Method for Predicting Biomarkers Associated with Prostate Cancer

  Yanqiu Tong, Zhongle Tan, Pu Wang, Xi Gao

  Front. Biosci. (Landmark Ed) 2023, 28(12), 333; https://doi.org/10.31083/j.fbl2812333

  Abstract Full Text PDF(20.35MB)

  69

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  273

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• Open Access Review

  Lipid Peroxidation in Ferroptosis and Association with Nonalcoholic Fatty Liver Disease

  Shengnan Zhao, Yan Guo, Xunzhe Yin

  Front. Biosci. (Landmark Ed) 2023, 28(12), 332; https://doi.org/10.31083/j.fbl2812332

  (This article belongs to the Special Issue Cellular and Molecular Mechanisms of Metabolic Liver Disease-associated Hepatocellular Carcinoma)

  Abstract Full Text PDF(12.05MB)

  114

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  318

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• Open Access Short Communication

  Examination of Bovine Red Blood Cell Death in Vitro in Response to Pathophysiologic Proapoptotic Stimuli

  Bailey Kennedy, Sonia Mirza, Tania Mandiangu, Rosi Bissinger, ... Syed M. Qadri

  Front. Biosci. (Landmark Ed) 2023, 28(12), 331; https://doi.org/10.31083/j.fbl2812331

  Abstract Full Text PDF(6.07MB)

  50

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  587

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• Open Access Original Research

  Transcriptome Mapping of the Internal N7-Methylguanosine Methylome in Messenger RNAs in Human Oral Squamous Cell Carcinoma

  Minmin Li, Ning Song, Dongyuan Sun, Yang Yu, ... Yingying Jiang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 330; https://doi.org/10.31083/j.fbl2812330

  (This article belongs to the Special Issue Mechanisms of Control and Inhibition of Genes in Most Aggressive Tumors: Pathways, Targets and Treatments)

  Abstract Full Text PDF(4.77MB)

  45

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  173

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• Open Access Original Research

  Community Structure and Diversity of Rhizosphere Soil and Endophytic Bacteria during the Period of Growth of Moso Bamboo Shoots

  Zongsheng Yuan, Fang Liu, Zhi-hao Zeng, Hui Pan

  Front. Biosci. (Landmark Ed) 2023, 28(12), 329; https://doi.org/10.31083/j.fbl2812329

  Abstract Full Text PDF(6.24MB)

  30

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  92

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• Open Access Original Research

  Metabolism-Related Prognostic Biomarkers, Purine Metabolism and Anti-Tumor Immunity in Colon Adenocarcinoma

  Hui Liu, Yuexin Zhang, Quanzheng Zhang, Tongtong Zhang, Tianqi Lu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 328; https://doi.org/10.31083/j.fbl2812328

  Abstract Full Text PDF(3.88MB)

  59

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  221

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• Open Access Original Research

  Quercetin/Anti-PD-1 Antibody Combination Therapy Regulates the Gut Microbiota, Impacts Macrophage Immunity and Reshapes the Hepatocellular Carcinoma Tumor Microenvironment

  Ruoxia Wu, Jiaqing Xiong, Ting Zhou, Zhen Zhang, ... Yongli Wang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 327; https://doi.org/10.31083/j.fbl2812327

  Abstract Full Text PDF(10.14MB)

  84

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  231

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• Open Access Original Research

  Anti-Inflammatory Effects of Chaenomeles sinensis Extract in an ALS Animal Model

  Eun Jin Yang, Sun Hwa Lee

  Front. Biosci. (Landmark Ed) 2023, 28(12), 326; https://doi.org/10.31083/j.fbl2812326

  Abstract Full Text PDF(3.39MB)

  40

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• Open Access Original Research

  Maintenance of the Expression of c-FLIP_L by Hsp70 to Resist Licochalcone A-Induced Anti-Colorectal Cancer Effect through ERK-Mediated Autophagy Induction

  Tianpeng Li, Ting Li, Hongbin Zhang, Chunyan Liu, ... Wei Chen

  Front. Biosci. (Landmark Ed) 2023, 28(12), 325; https://doi.org/10.31083/j.fbl2812325

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(5.47MB)

  23

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  125

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• Open Access Original Research

  EGCG Restores Keratinocyte Autophagy to Promote Diabetic Wound Healing through the AMPK/ULK1 Pathway

  Chao Tian, Yuchao Feng, Tianhua Chen, Zuyang Zhang, ... Mingjiang Liu

  Front. Biosci. (Landmark Ed) 2023, 28(12), 324; https://doi.org/10.31083/j.fbl2812324

  (This article belongs to the Special Issue Plant Bioactive Molecules)

  Abstract Full Text PDF(14.28MB)

  46

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  168

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• Open Access Original Research

  Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway

  Bi-Ying Zhou, Jing Yang, Rui-Rui Luo, Yan-Lin Sun, ... Guo-Xing Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(12), 323; https://doi.org/10.31083/j.fbl2812323

  (This article belongs to the Special Issue Mechanisms of Protection and/or Therapy for Ischemia and Reperfusion Injury in the Brain, Spinal Cord, Heart, Liver, and Kidney)

  Abstract Full Text PDF(5.29MB)

  46

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  173

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• Open Access Original Research

  ProSE-Pero: Peroxisomal Protein Localization Identification Model Based on Self-Supervised Multi-Task Language Pre-Training Model

  Jianan Sui, Jiazi Chen, Yuehui Chen, Naoki Iwamori, Jin Sun

  Front. Biosci. (Landmark Ed) 2023, 28(12), 322; https://doi.org/10.31083/j.fbl2812322

  Abstract Full Text PDF(15.03MB)

  36

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