Volume 28 Issue 12 2023 - (December 2023)

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Open Access Notice of Withdrawal

Notice of Withdrawal

FBL Editorial Office

Front. Biosci. (Landmark Ed) 2023, 28(12), 369; https://doi.org/10.31083/j.fbl2812369

Abstract PDF(138.55KB)

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Open Access Original Research

RIPK4 Promotes Cell Invasion and the Epithelial–Mesenchymal Transition in Ovarian Cancer

Li Hua, Jian-Hai Wu, Jing-Ying Xu, San-Gang Wu, Juan Zhou

Front. Biosci. (Landmark Ed) 2023, 28(12), 368; https://doi.org/10.31083/j.fbl2812368

Abstract Full Text PDF(5.97MB)

107

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1

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379

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Open Access Original Research

Canthaxanthin Attenuates the Vascular Aging or Endothelial Cell Senescence by Inhibiting Inflammation and Oxidative Stress in Mice

Zhefeng Wang, Lilin Li, Souqi Liao, Ren Huang, ... Keda Zhang

Front. Biosci. (Landmark Ed) 2023, 28(12), 367; https://doi.org/10.31083/j.fbl2812367

Abstract Full Text PDF(7.13MB)

117

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5

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420

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Open Access Original Research

Plant-Derived Extracts Plus Vitamin E and/or Aloe Vera Protect Against Intrinsic/Extrinsic Stressor in Human Skin: In Vitro and Clinical Evidence

Ganesh Diwakar, Lisa Barnes, Melanie Riggs, Helen Knaggs, Zoe Diana Draelos

Front. Biosci. (Landmark Ed) 2023, 28(12), 366; https://doi.org/10.31083/j.fbl2812366

Abstract Full Text PDF(2.27MB)

180

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1

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434

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Open Access Original Research

Transcriptome and Pathway Analysis Reveals that Adipose-derived Stem Cells Target Inflammatory Factors and Delay the Progression of Diabetic Liver Disease

Yanli Hou, Guoliang Gao, Wenyu Ding, Peishan Wu, ... Xiaolei Wang

Front. Biosci. (Landmark Ed) 2023, 28(12), 365; https://doi.org/10.31083/j.fbl2812365

(This article belongs to the Special Issue Research Trend of the Inflammasome Regulation)

Abstract Full Text PDF(12.53MB)

60

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226

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Open Access Review

Gene Silencing and Gene Delivery in Therapeutics: Insights Using Quantum Dots

Shrodha Mondal, Jiko Raut, Prithidipa Sahoo

Front. Biosci. (Landmark Ed) 2023, 28(12), 364; https://doi.org/10.31083/j.fbl2812364

Abstract Full Text PDF(19.86MB)

198

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8

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365

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Open Access Review

Biological Immune Mechanism of Retina

Xingyu Zhu, Jiaxu Hong, Xujiao Zhou

Front. Biosci. (Landmark Ed) 2023, 28(12), 363; https://doi.org/10.31083/j.fbl2812363

(This article belongs to the Special Issue Retinal Biology in Health and Disease)

Abstract Full Text PDF(229.27KB)

384

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12

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711

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Open Access Review

Cancer Stem Cell Biomarkers in the Nervous System

Xinyi Li, Jiaqiang Huang, Yulin Kang, Xiyu Cheng, ... Hanli Xu

Front. Biosci. (Landmark Ed) 2023, 28(12), 362; https://doi.org/10.31083/j.fbl2812362

Abstract Full Text PDF(5.35MB)

156

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5

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361

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Open Access Review

An Update on Gemcitabine-Based Chemosensitization Strategies in Pancreatic Ductal Adenocarcinoma

Tianpeng Zhang, Zongting Gu, Ran Ni, Xiao Wang, ... Ran Tao

Front. Biosci. (Landmark Ed) 2023, 28(12), 361; https://doi.org/10.31083/j.fbl2812361

(This article belongs to the Special Issue New Targets in Anticancer Therapy)

Abstract Full Text PDF(1.11MB)

103

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4

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289

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Open Access Original Research

Bioinformatic Analysis and Computer-Aided Study to Investigate the Potential Application of a Bioflavonoid Compound Bilobetin in Liver Cancer Treatment

Chunye Zhang, Yuxiang Sui, Shuai Liu, Ming Yang

Front. Biosci. (Landmark Ed) 2023, 28(12), 360; https://doi.org/10.31083/j.fbl2812360

Abstract Full Text PDF(10.02MB)

494

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1

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1346

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Open Access Review

Stem Cell Therapy for Liver Diseases: Current Perspectives

Jing Wang, Qun Li, Wenbo Li, Nahum Méndez-Sánchez, ... Xingshun Qi

Front. Biosci. (Landmark Ed) 2023, 28(12), 359; https://doi.org/10.31083/j.fbl2812359

Abstract Full Text PDF(813.35KB)

344

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6

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570

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Open Access Original Research

Clinical Assessment of Cytokine Profiles and Haematological Parameters in Patients with Systemic Lupus Erythematosus: A Cross-Sectional Study from Saudi Arabia

Fahad M. Aldakheel, Muwaffaq A. Alshanqiti, Shatha A. Alduraywish, Amal F. Alshammary, ... Rabbani Syed

Front. Biosci. (Landmark Ed) 2023, 28(12), 358; https://doi.org/10.31083/j.fbl2812358

(This article belongs to the Special Issue Cytokines in Health and Disease)

Abstract Full Text PDF(247.04KB)

86

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5

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289

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Open Access Review

Cellular Senescence in Non-Small Cell Lung Cancer

Huangkai Zhu, Jiaen Sun, Chong Zhang, Pei Li, ... Guofang Zhao

Front. Biosci. (Landmark Ed) 2023, 28(12), 357; https://doi.org/10.31083/j.fbl2812357

Abstract Full Text PDF(256.92KB)

214

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13

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536

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Open Access Review

Inflammation and Late-Life Depression: Unraveling the Complex Relationship and Potential Therapeutic Strategies

Jian Xia, Meiling Chen, Heng Shao, Hui Chen, ... Shaoyuan Wu

Front. Biosci. (Landmark Ed) 2023, 28(12), 356; https://doi.org/10.31083/j.fbl2812356

Abstract Full Text PDF(565.45KB)

209

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11

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528

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Open Access Review

A More Holistic Perspective of Alzheimer's Disease: Roles of Gut Microbiome, Adipocytes, HPA Axis, Melatonergic Pathway and Astrocyte Mitochondria in the Emergence of Autoimmunity

George Anderson

Front. Biosci. (Landmark Ed) 2023, 28(12), 355; https://doi.org/10.31083/j.fbl2812355

(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

Abstract Full Text PDF(1.53MB)

338

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16

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712

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Open Access Original Research

Effects of Purine Metabolism-Related LINC01671 on Tumor Heterogeneity in Kidney Renal Clear Cell Carcinoma

Wei Yin, Jin-Hua Wang, Yu-Mei Liang, Kang-Han Liu, ... Yu-Sa Chen

Front. Biosci. (Landmark Ed) 2023, 28(12), 354; https://doi.org/10.31083/j.fbl2812354

Abstract Full Text PDF(11.34MB)

59

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3

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270

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Open Access Original Research

Assessment of Phenolic Composition, Antioxidant Potential, Antimicrobial Properties, and Antidiabetic Activity in Extracts Obtained from Schinus molle L. Leaves and Fruits

Selen İlgün, Gökçe Şeker Karatoprak, Derya Çiçek Polat, Esra Köngül Şafak, ... Esra Küpeli Akkol

Front. Biosci. (Landmark Ed) 2023, 28(12), 353; https://doi.org/10.31083/j.fbl2812353

(This article belongs to the Special Issue Plant Bioactive Molecules)

Abstract Full Text PDF(1013.66KB)

216

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7

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431

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Open Access Original Research

Sequence Analysis of the Plastomes of Two Tibetan Medicinal Plants of the Family Papaveraceae

Danyang Wu, Qian Qin, Xiaoyun Wang, Yiming Niu, ... Zejing Mu

Front. Biosci. (Landmark Ed) 2023, 28(12), 352; https://doi.org/10.31083/j.fbl2812352

Abstract Full Text PDF(4.31MB)

39

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1

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181

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Open Access Review

FGF21: A Sharp Weapon in the Process of Exercise to Improve NAFLD

Zhiyuan Wang, Tingting Sun, Jingjing Yu, Siyu Li, ... Yimin Zhang

Front. Biosci. (Landmark Ed) 2023, 28(12), 351; https://doi.org/10.31083/j.fbl2812351

Abstract Full Text PDF(3.38MB)

423

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6

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853

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Open Access Review

The Role of Nucleoporins in Cardiac Tissue Development and Disease

Xiaocong Chen, Rui Shi, Yu Luo, Liang Xu

Front. Biosci. (Landmark Ed) 2023, 28(12), 350; https://doi.org/10.31083/j.fbl2812350

Abstract Full Text PDF(1.01MB)

52

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1

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240

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Open Access Original Research

Unlocking the Potential: Synergistic Effects of Solid SNEDDS and Lyophilized Solid Dispersion to Enhance Stability Attributes

Ahmad Yousef Tashish, Ahmad Abdul-Wahhab Shahba, Fars Kaed Alanazi, Mohsin Kazi

Front. Biosci. (Landmark Ed) 2023, 28(12), 349; https://doi.org/10.31083/j.fbl2812349

(This article belongs to the Special Issue Recent Developments in Drug Delivery)

Abstract Full Text PDF(4.24MB)

105

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7

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254

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Open Access Review

Fatty Acid Metabolism: A New Perspective in Breast Cancer Precision Therapy

Mengye He, Suzhen Xu, Feifei Yan, Jian Ruan, Xiaochen Zhang

Front. Biosci. (Landmark Ed) 2023, 28(12), 348; https://doi.org/10.31083/j.fbl2812348

Abstract Full Text PDF(1.09MB)

381

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15

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776

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Open Access Original Research

GluN2A Mediates PS-Induced Depressive-Like Behavior by Activating CaMKII and Inhibiting Myelinization

Huimei Huang, Hongli Jiang, Hongli Sun

Front. Biosci. (Landmark Ed) 2023, 28(12), 347; https://doi.org/10.31083/j.fbl2812347

Abstract Full Text PDF(19.78MB)

72

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1

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236

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Open Access Original Research

im5C-DSCGA: A Proposed Hybrid Framework Based on Improved DenseNet and Attention Mechanisms for Identifying 5-methylcytosine Sites in Human RNA

Jianhua Jia, Lulu Qin, Rufeng Lei

Front. Biosci. (Landmark Ed) 2023, 28(12), 346; https://doi.org/10.31083/j.fbl2812346

Abstract Full Text PDF(11.55MB)

70

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3

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195

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Open Access Original Research

Metabolite Profiling and Comparative Metabolomics Analysis of Jiaozhou Chinese Cabbage (Brassica rapa L. ssp. pekinensis) Planted in Different Areas

Jingjuan Li, Minghui Qiu, Faujiah Nurhasanah Ritonga, Fengde Wang, ... Jianwei Gao

Front. Biosci. (Landmark Ed) 2023, 28(12), 345; https://doi.org/10.31083/j.fbl2812345

Abstract Full Text PDF(1.44MB)

110

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2

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368

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Open Access Original Research

ATF4 Responds to Metabolic Stress in Drosophila

Soonhyuck Ok, Jung-Eun Park, Seunghee Byun, Kwonyoon Kang, ... Min-Ji Kang

Front. Biosci. (Landmark Ed) 2023, 28(12), 344; https://doi.org/10.31083/j.fbl2812344

Abstract Full Text PDF(5.91MB)

153

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4

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521

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Open Access Original Research

Identification of Biomarker IL2Rβ in Ankylosing Spondylitis via Multi-Chip Integration Analysis of Gene Differential Expression

Bin Xiao, Peng-Lei Cui, Hong-Chao Li, Chao Wang, ... Cheng-Ai Wu

Front. Biosci. (Landmark Ed) 2023, 28(12), 343; https://doi.org/10.31083/j.fbl2812343

Abstract Full Text PDF(4.63MB)

56

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239

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Open Access Original Research

DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice

Linqiao Li, Feixiang Ling, Rou Li, Yan Jiang, ... Libing Ma

Front. Biosci. (Landmark Ed) 2023, 28(12), 342; https://doi.org/10.31083/j.fbl2812342

Abstract Full Text PDF(8.83MB)

178

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5

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619

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Open Access Original Research

Exploration of the Pharmacological Mechanism of Vitexicarpin against Triple-Negative Breast Cancer in Network Pharmacology

Tianhui Wu, Min Xiang, Yujiao Li, Yahan Gao, ... Yuanshuai Zhou

Front. Biosci. (Landmark Ed) 2023, 28(12), 341; https://doi.org/10.31083/j.fbl2812341

Abstract Full Text PDF(5.94MB)

92

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3

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365

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Open Access Original Research

An Insight into Biochemical Characterization and Explorations of Antioxidant, Antibacterial, Cytotoxic, and Antidiabetic Activities by Trachyspermum ammi Nanosuspensions

Rizwana Jabeen, Tayyab Ali, Muhammad Naeem, Fatma Hussain, ... Mohammad Javed Ansari

Front. Biosci. (Landmark Ed) 2023, 28(12), 340; https://doi.org/10.31083/j.fbl2812340

Abstract Full Text PDF(9.83MB)

134

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4

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367

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Open Access Original Research

Transcriptome-Wide Dynamics of m7G-Related LncRNAs during the Progression from HBV Infection to Hepatocellular Carcinoma

Min Shi, Shunshun Zhu, Linying Sun, Jieli Hu, ... Tao Guo

Front. Biosci. (Landmark Ed) 2023, 28(12), 339; https://doi.org/10.31083/j.fbl2812339

Abstract Full Text PDF(7.00MB)

73

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4

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319

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Open Access Original Research

High MEIS3 Expression Indicates a Poor Prognosis for Patients with Stage II/III Colorectal Cancer

Jian Ma, Haitao Li, Qianqian Gao, Weixing Zhang, ... Ziyan Li

Front. Biosci. (Landmark Ed) 2023, 28(12), 338; https://doi.org/10.31083/j.fbl2812338

(This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

Abstract Full Text PDF(3.53MB)

57

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2

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266

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Open Access Original Research

A Study on the Pharmacological Effects and Mechanism of Rhodojaponin III in Rheumatoid Arthritis

Xiaorong Liu, Shuofu Li, Yin Xu, Wenya Mei, Ribao Zhou

Front. Biosci. (Landmark Ed) 2023, 28(12), 337; https://doi.org/10.31083/j.fbl2812337

Abstract Full Text PDF(27.47MB)

95

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3

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302

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Open Access Original Research

Genotypic Characterization of a Chinese Family with Osteogenesis Imperfecta and Generation of Disease-Specific Induced Pluripotent Stem Cells

Dandan Li, Minglin Ou, Guandong Dai, Peng Zhu, ... Yong Dai

Front. Biosci. (Landmark Ed) 2023, 28(12), 336; https://doi.org/10.31083/j.fbl2812336

Abstract Full Text PDF(3.67MB)

101

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1

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380

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Open Access Original Research

Influence of Age, Heart Failure and ACE Inhibitor Treatment on Plasma Renin Activity in Children: Insights from a Systematic Review and the European LENA Project

Melina Steichert, Willi Cawello, Milica Bajcetic, Johannes M.P.J. Breur, ... on behalf of the LENA Consortium

Front. Biosci. (Landmark Ed) 2023, 28(12), 335; https://doi.org/10.31083/j.fbl2812335

Abstract Full Text PDF(4.06MB)

198

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1

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450

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Open Access Original Research

Pyroptosis-Related Subtypes Predict the Response of Clear Cell Renal Cell Carcinoma to Targeted Therapy

Jinpeng Ma, Zhijian Kang, Guang Yang, Xinyue Wang, ... Wanhai Xu

Front. Biosci. (Landmark Ed) 2023, 28(12), 334; https://doi.org/10.31083/j.fbl2812334

Abstract Full Text PDF(10.59MB)

140

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10

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455

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Open Access Original Research

A Machine Learning Method for Predicting Biomarkers Associated with Prostate Cancer

Yanqiu Tong, Zhongle Tan, Pu Wang, Xi Gao

Front. Biosci. (Landmark Ed) 2023, 28(12), 333; https://doi.org/10.31083/j.fbl2812333

Abstract Full Text PDF(20.35MB)

214

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5

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514

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Open Access Review

Lipid Peroxidation in Ferroptosis and Association with Nonalcoholic Fatty Liver Disease

Shengnan Zhao, Yan Guo, Xunzhe Yin

Front. Biosci. (Landmark Ed) 2023, 28(12), 332; https://doi.org/10.31083/j.fbl2812332

(This article belongs to the Special Issue Cellular and Molecular Mechanisms of Metabolic Liver Disease-associated Hepatocellular Carcinoma)

Abstract Full Text PDF(12.05MB)

397

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11

Citations

952

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Open Access Short Communication

Examination of Bovine Red Blood Cell Death in Vitro in Response to Pathophysiologic Proapoptotic Stimuli

Bailey Kennedy, Sonia Mirza, Tania Mandiangu, Rosi Bissinger, ... Syed M. Qadri

Front. Biosci. (Landmark Ed) 2023, 28(12), 331; https://doi.org/10.31083/j.fbl2812331

Abstract Full Text PDF(6.07MB)

124

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1

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867

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Open Access Original Research

Transcriptome Mapping of the Internal N7-Methylguanosine Methylome in Messenger RNAs in Human Oral Squamous Cell Carcinoma

Minmin Li, Ning Song, Dongyuan Sun, Yang Yu, ... Yingying Jiang

Front. Biosci. (Landmark Ed) 2023, 28(12), 330; https://doi.org/10.31083/j.fbl2812330

(This article belongs to the Special Issue Mechanisms of Control and Inhibition of Genes in Most Aggressive Tumors: Pathways, Targets and Treatments)

Abstract Full Text PDF(4.77MB)

91

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1

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371

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Open Access Original Research

Community Structure and Diversity of Rhizosphere Soil and Endophytic Bacteria during the Period of Growth of Moso Bamboo Shoots

Zongsheng Yuan, Fang Liu, Zhi-hao Zeng, Hui Pan

Front. Biosci. (Landmark Ed) 2023, 28(12), 329; https://doi.org/10.31083/j.fbl2812329

Abstract Full Text PDF(6.24MB)

96

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3

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251

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Open Access Original Research

Metabolism-Related Prognostic Biomarkers, Purine Metabolism and Anti-Tumor Immunity in Colon Adenocarcinoma

Hui Liu, Yuexin Zhang, Quanzheng Zhang, Tongtong Zhang, Tianqi Lu

Front. Biosci. (Landmark Ed) 2023, 28(12), 328; https://doi.org/10.31083/j.fbl2812328

Abstract Full Text PDF(3.88MB)

125

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3

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585

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Open Access Original Research

Quercetin/Anti-PD-1 Antibody Combination Therapy Regulates the Gut Microbiota, Impacts Macrophage Immunity and Reshapes the Hepatocellular Carcinoma Tumor Microenvironment

Ruoxia Wu, Jiaqing Xiong, Ting Zhou, Zhen Zhang, ... Yongli Wang

Front. Biosci. (Landmark Ed) 2023, 28(12), 327; https://doi.org/10.31083/j.fbl2812327

Abstract Full Text PDF(10.14MB)

300

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23

Citations

782

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Open Access Original Research

Anti-Inflammatory Effects of Chaenomeles sinensis Extract in an ALS Animal Model

Eun Jin Yang, Sun Hwa Lee

Front. Biosci. (Landmark Ed) 2023, 28(12), 326; https://doi.org/10.31083/j.fbl2812326

Abstract Full Text PDF(3.39MB)

79

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6

Citations

272

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Open Access Original Research

Maintenance of the Expression of c-FLIP_L by Hsp70 to Resist Licochalcone A-Induced Anti-Colorectal Cancer Effect through ERK-Mediated Autophagy Induction

Tianpeng Li, Ting Li, Hongbin Zhang, Chunyan Liu, ... Wei Chen

Front. Biosci. (Landmark Ed) 2023, 28(12), 325; https://doi.org/10.31083/j.fbl2812325

(This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

Abstract Full Text PDF(5.47MB)

47

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247

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Open Access Original Research

EGCG Restores Keratinocyte Autophagy to Promote Diabetic Wound Healing through the AMPK/ULK1 Pathway

Chao Tian, Yuchao Feng, Tianhua Chen, Zuyang Zhang, ... Mingjiang Liu

Front. Biosci. (Landmark Ed) 2023, 28(12), 324; https://doi.org/10.31083/j.fbl2812324

(This article belongs to the Special Issue Plant Bioactive Molecules)

Abstract Full Text PDF(14.28MB)

198

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10

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601

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Open Access Original Research

Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway

Bi-Ying Zhou, Jing Yang, Rui-Rui Luo, Yan-Lin Sun, ... Guo-Xing Zhang

Front. Biosci. (Landmark Ed) 2023, 28(12), 323; https://doi.org/10.31083/j.fbl2812323

(This article belongs to the Special Issue Mechanisms of Protection and/or Therapy for Ischemia and Reperfusion Injury in the Brain, Spinal Cord, Heart, Liver, and Kidney)

Abstract Full Text PDF(5.29MB)

143

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14

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447

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Open Access Original Research

ProSE-Pero: Peroxisomal Protein Localization Identification Model Based on Self-Supervised Multi-Task Language Pre-Training Model

Jianan Sui, Jiazi Chen, Yuehui Chen, Naoki Iwamori, Jin Sun

Front. Biosci. (Landmark Ed) 2023, 28(12), 322; https://doi.org/10.31083/j.fbl2812322

Abstract Full Text PDF(15.03MB)

70

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1

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228

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Front. Biosci. (Landmark Ed) Print ISSN 2768-6701 Electronic ISSN 2768-6698