Announcements
Volume 30 Issue 10 2025 - (October 2025)
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- Open Access Original ResearchIdentification of Diagnostic Biomarkers Associated With M1 Macrophage in Lung Squamous Cell Carcinoma via Machine LearningHuiting Deng, Zhenling Wang, Qiangzhe ZhangFront. Biosci. (Landmark Ed) 2025, 30(10), 44661; https://doi.org/10.31083/FBL4466156Downloads166Views
- Open Access ReviewTemporal Orchestration of Immunity: How Circadian Clocks Coordinate Immune ResponsesYunxin Jiang, Chao Liu, Yingbin ZhongFront. Biosci. (Landmark Ed) 2025, 30(10), 39948; https://doi.org/10.31083/FBL3994896Downloads293Views
- Open Access ReviewIonizing Radiation in Clinical Diagnostics and Radiotherapy: The Dual Role of NRF2 in Cell Protection and CarcinogenesisAlessandra Verdina, Gabriella D’OraziFront. Biosci. (Landmark Ed) 2025, 30(10), 39800; https://doi.org/10.31083/FBL39800(This article belongs to the Special Issue NRF2 and Cancer)40Downloads78Views
- Open Access Original ResearchA Comparative Study of the Effects of Nine CXCR3 Antagonists on Macrophage Function and the Treatment of Acute Lung InjuryMengjie Zhang, Ziyu Wan, Zefeng Zhu, Pengbin Wang, ... Wei GuFront. Biosci. (Landmark Ed) 2025, 30(10), 45931; https://doi.org/10.31083/FBL4593139Downloads119Views
- Open Access Original ResearchMetabolomics Profiling of Kidney, Spleen, Lung, and Liver Tissues in a Mouse Model of SepsisMoongi Ji, Byeongchan Choi, Chanho Kim, Jaeyeop Lim, Man-Jeong PaikFront. Biosci. (Landmark Ed) 2025, 30(10), 45558; https://doi.org/10.31083/FBL4555871Downloads114Views
- Open Access Original ResearchChanges of Microglial Cells in the Progression of Neurodegeneration in Natural Prion DiseaseMarta Monzón, Juan Sauca Pérez, Rodrigo S. Hernández, Rocío Sarasa, ... Juan J BadiolaFront. Biosci. (Landmark Ed) 2025, 30(10), 47074; https://doi.org/10.31083/FBL4707431Downloads93Views
- Open Access Original ResearchGenomic Instability is Widespread in Esophageal Squamous Dysplasia and Increases During the Progression to CancerHaiyin An, Xian Cheng, Liyan Xue, Guiqi Wang, ... Shujun ChengFront. Biosci. (Landmark Ed) 2025, 30(10), 41107; https://doi.org/10.31083/FBL4110727Downloads97Views
- Open Access Original ResearchCathepsin S Contributes to Bladder Fibrosis Following Bladder Outlet Obstruction via IL-6 Trans-signalingMengchen Yang, Xilei Liu, Hong Wang, Tianyu Shen, Liang WangFront. Biosci. (Landmark Ed) 2025, 30(10), 45355; https://doi.org/10.31083/FBL4535528Downloads85Views
- Open Access Original ResearchStudy on the Mechanism of CCN2 Promoting Sorafenib Resistance in HCC and Its Combined Intervention StrategyLei Cui, Junhao Liu, Yongxue Lv, Bendong Chen, ... Yang BuFront. Biosci. (Landmark Ed) 2025, 30(10), 45454; https://doi.org/10.31083/FBL4545422Downloads79Views
- Open Access ReviewGlutamate Excitotoxicity: A Key Secondary Injury Mechanism of Traumatic Brain Injury and Spinal Cord InjuryJiamei Hou, Kelena Klippel, Prodip BoseFront. Biosci. (Landmark Ed) 2025, 30(10), 38904; https://doi.org/10.31083/FBL38904(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions of Neurological and Neuropsychiatric Disorders - Volume 2)61Downloads160Views
- Open Access Original ResearchUrinary Metabolomics-Driven Discovery of Metabolic Markers and Molecular Subtyping in Liver CancerHemeng Wu, Hongsheng Lin, Fuli Long, Rongzhen Zhang, ... Xiaoling ZhouFront. Biosci. (Landmark Ed) 2025, 30(10), 45438; https://doi.org/10.31083/FBL4543845Downloads84Views
- Open Access OpinionBeyond Passive Bystander: Glioblastoma-Educated Astrocyte Suppressing T CellYuan-Yuan Wang, Wei-Lin JinFront. Biosci. (Landmark Ed) 2025, 30(10), 44810; https://doi.org/10.31083/FBL4481046Downloads118Views
- Open Access ReviewTargeting Ferroptosis: New Insights and Therapeutic Advances in MAFLD Complicating T2DMFang Yao, Gaochao Wang, Fan Ning, Yanbo ShiFront. Biosci. (Landmark Ed) 2025, 30(10), 39735; https://doi.org/10.31083/FBL3973556Downloads88Views
- Open Access Original ResearchBRD4-S Drives Colorectal Cancer Progression via DDX27-Regulated Splicing and MAPK Signaling ActivationChenlu Wang, Hong Hong, Lining Zhou, Fuying Chu, Xiang ChenFront. Biosci. (Landmark Ed) 2025, 30(10), 46158; https://doi.org/10.31083/FBL46158(This article belongs to the Special Issue Transcriptional Regulation in Cancer)39Downloads95Views
- Open Access ReviewPharmacological Modulation of NLRP3: From Therapy Personalization to Innovative DrugsGiulia Zudeh, Sara Sossai, Jacopo Angelini, Gabriele Stocco, Marianna LucafòFront. Biosci. (Landmark Ed) 2025, 30(10), 39537; https://doi.org/10.31083/FBL3953736Downloads110Views
- Open Access ReviewArtificial Intelligence in the Evolution of Interventional Therapy for Liver Cancer: Navigating the Tumor MicroenvironmentZhe Xiu, Wenlong Zeng, Jianyang Guo, Guirong Tu, ... Huangxiang ChenFront. Biosci. (Landmark Ed) 2025, 30(10), 37633; https://doi.org/10.31083/FBL3763316Downloads51Views
- Open Access Original ResearchComplete Genome Sequence Analysis of the Bacterial Wilt Disease Pathogen Ralstonia pseudosolanacearum Strain MLY158Junxian Zou, Guan Lin, Juntao Gao, Denghui Li, ... Xingjiang ChenFront. Biosci. (Landmark Ed) 2025, 30(10), 46230; https://doi.org/10.31083/FBL4623019Downloads62Views
- Open Access Original ResearchANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein DegradationYuanyuan Guo, Xianghui Fu, Yan TianFront. Biosci. (Landmark Ed) 2025, 30(10), 46013; https://doi.org/10.31083/FBL4601320Downloads63Views
- Open Access Original ResearchDeciphering the Role of KIF18A in Osteosarcoma Progression: An Integrative Analysis and Experimental ValidationZhiqian Gu, Songou Zhang, Xudong Hu, Nanjian Xu, ... Hong ChenFront. Biosci. (Landmark Ed) 2025, 30(10), 44663; https://doi.org/10.31083/FBL4466320Downloads80Views
- Open Access Original ResearchSENP5 Attenuates LPS-Induced Acute Lung Injury by Inhibiting Apoptosis of Lung Epithelial Cells Through SLC7A5/mTOR Signaling PathwayYiran He, Hai Zhang, Jianmin Gu, Minjie Ju, Chunbing ZhangFront. Biosci. (Landmark Ed) 2025, 30(10), 45811; https://doi.org/10.31083/FBL4581131Downloads89Views
- Open Access ReviewHIV-1 Entry Mechanisms: Protein-Host Receptor Interactions and Membrane Fusion DynamicsAmir Elalouf, Hadas Elalouf, Hanan MaozFront. Biosci. (Landmark Ed) 2025, 30(10), 37412; https://doi.org/10.31083/FBL3741296Downloads116Views
- Open Access Original ResearchAstragalus Polysaccharide Improves Myocardial Fibrosis in Hypertrophic Cardiomyopathy Through the TGF-β1/Smad3 Signal PathwayNana Qin, Wenjun Wu, Baoyin LiFront. Biosci. (Landmark Ed) 2025, 30(10), 45595; https://doi.org/10.31083/FBL4559533Downloads102Views
- Open Access ReviewMacrophages in Lupus Nephritis: Insights into Its Pathogenesis and Emerging TreatmentsLu Zhang, Jianpeng Sheng, Ting LiuFront. Biosci. (Landmark Ed) 2025, 30(10), 39365; https://doi.org/10.31083/FBL3936556Downloads73Views
- Open Access ReviewThe Impact of Splicing Factor Mutations on Clonal Hematopoiesis and Myeloid Neoplasm ProgressionTakuya Izumi-Tamura, Asuka Kawachi, Akihide YoshimiFront. Biosci. (Landmark Ed) 2025, 30(10), 38825; https://doi.org/10.31083/FBL3882531Downloads140Views
- Open Access Original ResearchCalcitonin Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting the HMGB1/MyD88/NF-κB Pathway by Targeting CD3DHongyan Zhang, Ruiqing Zong, Huiqi Wu, Jun Jiang, Jian HeFront. Biosci. (Landmark Ed) 2025, 30(10), 44677; https://doi.org/10.31083/FBL4467729Downloads107Views
- Open Access ReviewFrom Bench to Motion: Unraveling Exercise Biology Through 3D Human OrganoidsLimin Xu, Yu Wang, Chenshi Xi, Jingqi Liu, ... Lina SunFront. Biosci. (Landmark Ed) 2025, 30(10), 40854; https://doi.org/10.31083/FBL4085437Downloads98Views
- Open Access Original ResearchAn Anoikis-Based Prognostic Signature Identifies MYC as a Key Regulator of Malignancy and Immunotherapy Resistance in Bladder CancerZhen Tang, Jiao Peng, Xiaoyu Pan, Yuefeng Kong, ... Siping ZengFront. Biosci. (Landmark Ed) 2025, 30(10), 45386; https://doi.org/10.31083/FBL4538637Downloads92Views
- Open Access OpinionAdaptability Beyond Darwin: Microbial Evolution, Mitochondria, and the Thermodynamic Frontiers of SurvivalGeorge B. StefanoFront. Biosci. (Landmark Ed) 2025, 30(10), 45962; https://doi.org/10.31083/FBL4596230Downloads87Views
- Open Access ReviewBiophysical Properties of the Extracellular Matrix in Cancer: Insights Into ImmunotherapyXiang Zheng, Famin Ke, Mingxuan Yao, Hanyu Yang, ... Qiuyu LiuFront. Biosci. (Landmark Ed) 2025, 30(10), 44127; https://doi.org/10.31083/FBL4412754Downloads153Views
- Open Access Original Researchpolr2i is Required for Zebrafish Early Cardiac DevelopmentYukun Chen, Qiuping Zhang, Xiaoyan Peng, Xinrui Wang, ... Yuqing LeiFront. Biosci. (Landmark Ed) 2025, 30(10), 44633; https://doi.org/10.31083/FBL4463354Downloads141Views