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- Academic Editor
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Background: Trachyspermum ammi is a frequently utilized
traditional medicinal plant renowned for its pharmacological attributes,
particularly in the realm of treating infectious diseases. This current study
aims to comprehensively assess the in vitro properties of freshly
prepared nanosuspensions derived from Trachyspermum ammi extracts, with
a focus on their cost-effective potential in various areas, including
antioxidant, antibacterial, cytotoxic, and antidiabetic activities.
Methods: Biochemical characterization of T. ammi
nanosuspensions by high-performance liquid chromatography (HPLC) and
Fourier-transform infrared spectroscopy (FTIR) analyses. Results: HPLC
analysis revealed the presence of kaempferol and sinapic acid in various amounts
at 11.5 ppm and 12.3 ppm, respectively. FTIR analysis of T. ammi powder
revealed the presence of alcohols and amines. The assessment of antioxidant
activity was conducted using a DPPH scavenging assay, indicating that the
nanosuspensions exhibited their highest free radical scavenging activity,
reaching 14.9%. Nanosuspensions showed 3.75