Volume 28 Issue 9 2023 - (September 2023)

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Open Access Review

Role of Toll-Like Receptors in Common Infectious Diseases of the Female Lower Genital Tract

Xinwei Zhao, Wenhua Jiang, Ximing Jin, Wenjia Wang, ... Zhuo Chen

Front. Biosci. (Landmark Ed) 2023, 28(9), 232; https://doi.org/10.31083/j.fbl2809232

Abstract Full Text PDF(4.00MB)

159

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5

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427

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Open Access Original Research

Effect of SKF96365 on Myocardial Fibrosis in Type-II Diabetic Rats

Huan-zhi Liu, Wei Wu

Front. Biosci. (Landmark Ed) 2023, 28(9), 231; https://doi.org/10.31083/j.fbl2809231

Abstract Full Text PDF(2.25MB)

107

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1

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363

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Open Access Original Research

Pan-Cancer Multi-Omics Analysis of Minichromosome Maintenance Proteins (MCMs) Expression in Human Cancers

Lulu Wang, Xiaowei Liu

Front. Biosci. (Landmark Ed) 2023, 28(9), 230; https://doi.org/10.31083/j.fbl2809230

(This article belongs to the Special Issue Multi-Omics Biomarker Signatures in Precision Cancer Medicine)

Abstract Full Text PDF(18.16MB)

106

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9

Citations

436

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Open Access Original Research

Expediting Multiple Biological Properties of Limonene and α-Pinene: Main Bioactive Compounds of Pistacia lentiscus L., Essential Oils

Nasreddine El Omari, Hanae Naceiri Mrabti, Taoufiq Benali, Riaz Ullah, ... Abdelhakim Bouyahya

Front. Biosci. (Landmark Ed) 2023, 28(9), 229; https://doi.org/10.31083/j.fbl2809229

(This article belongs to the Special Issue Perspectives of Essential Oils)

Abstract Full Text PDF(295.43KB)

236

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30

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517

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Open Access Original Research

Honey Mushroom, Armillaria mellea (Agaricomycetes) and Its Fermentation Products Target Regulation of OAT1/OAT3 Proteins to Reduce Hyperuricemia in Mice

Zheng-Long Li, Shu-Min Wang, Huan Wang

Front. Biosci. (Landmark Ed) 2023, 28(9), 228; https://doi.org/10.31083/j.fbl2809228

Abstract Full Text PDF(8.58MB)

119

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3

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389

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Open Access Original Research

Inhibition of TRAP1 Accelerates the DNA Damage Response, Activation of the Heat Shock Response and Metabolic Reprogramming in Colon Cancer Cells

Nobel Bhasin, Prerna Dabral, Lakmini Senavirathna, Sheng Pan, Ru Chen

Front. Biosci. (Landmark Ed) 2023, 28(9), 227; https://doi.org/10.31083/j.fbl2809227

Abstract Full Text PDF(2.26MB)

88

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7

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398

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Open Access Original Research

The Effects of Probiotic Lactobacillus rhamnosus GG on Fecal Flora and Serum Markers of Renal Injury in Mice with Chronic Kidney Disease

Lin Zhu, Jie Niu, Xiao-Cun Tang, Li-Hui Shan, ... Ping Zhou

Front. Biosci. (Landmark Ed) 2023, 28(9), 226; https://doi.org/10.31083/j.fbl2809226

Abstract Full Text PDF(4.17MB)

219

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8

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628

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Open Access Review

Impact of Immunosenescence on Viral Infections with an Emphasis on COVID-19

Giuseppe Murdaca, Francesca Paladin, Gabriella Martino, Sebastiano Gangemi

Front. Biosci. (Landmark Ed) 2023, 28(9), 225; https://doi.org/10.31083/j.fbl2809225

Abstract Full Text PDF(556.31KB)

225

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9

Citations

515

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Open Access Original Research

DNA Methylation Modification Patterns Identify Distinct Prognosis and Responses to Immunotherapy and Targeted Therapy in Renal Cell Carcinoma

Dan Bai, Yan Cheng, Xiaolan Lu, Ganesh Pandian Namasivayam, Hiroshi Sugiyama

Front. Biosci. (Landmark Ed) 2023, 28(9), 224; https://doi.org/10.31083/j.fbl2809224

Abstract Full Text PDF(9.98MB)

86

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3

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325

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Open Access Original Research

GLUT1 Mediates the Metabolic Reprogramming and Inflammation of CCR2⁺ Monocytes/Macrophages from Patients with DCM

Chao Feng, Hantao Jiang, Xueyuan Yang, Hongliang Cong, ... Jinping Feng

Front. Biosci. (Landmark Ed) 2023, 28(9), 223; https://doi.org/10.31083/j.fbl2809223

Abstract Full Text PDF(6.31MB)

196

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8

Citations

567

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Open Access Review

The Safety of Anti-VEGF Treatment, in the Context of the Retinal Nerve Fibre Layer, in Patients with Wet Age-Related Macular Degeneration: A Review

Małgorzata Wichrowska, Ewa Goździewska, Jarosław Kocięcki

Front. Biosci. (Landmark Ed) 2023, 28(9), 222; https://doi.org/10.31083/j.fbl2809222

(This article belongs to the Special Issue Retinal Biology in Health and Disease)

Abstract Full Text PDF(280.73KB)

176

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5

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450

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Open Access Review

Advances in Cardiac Organoids

Yu-Hong Wang, Qing Ouyang, Shuang Zhao, Yue Zhang, ... Ping Zhu

Front. Biosci. (Landmark Ed) 2023, 28(9), 221; https://doi.org/10.31083/j.fbl2809221

Abstract Full Text PDF(2.37MB)

393

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6

Citations

1050

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Open Access Original Research

NOTCH Pathway Genes in Ovarian Cancer: Clinical Significance and Associations with Immune Cell Infiltration

Buze Chen, Ke'er Jiang, Haihong Wang, Lu Miao, ... Xiaoyuan Lu

Front. Biosci. (Landmark Ed) 2023, 28(9), 220; https://doi.org/10.31083/j.fbl2809220

(This article belongs to the Special Issue Diagnostic, Prognostic, and Therapeutic Biomarkers for Ovarian Cancer)

Abstract Full Text PDF(12.58MB)

158

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5

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443

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Open Access Review

TP53 Mutations in Esophageal Squamous Cell Carcinoma

Leqi Zhong, Hongmu Li, Wuguang Chang, Yong Ao, ... Youfang Chen

Front. Biosci. (Landmark Ed) 2023, 28(9), 219; https://doi.org/10.31083/j.fbl2809219

(This article belongs to the Special Issue Advances in p53 Signaling and Cancer)

Abstract Full Text PDF(2.58MB)

379

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26

Citations

910

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Open Access Original Research

Identification and Analysis of Protein Family Associated with RNA Interference Pathway in Juglandaceae

Yuanpeng Fang, Jianming Wei, Xin Huang, Yunzhou Li, Xuejun Pan

Front. Biosci. (Landmark Ed) 2023, 28(9), 218; https://doi.org/10.31083/j.fbl2809218

(This article belongs to the Special Issue Genes Involved in Immune System Development)

Abstract Full Text PDF(7.33MB)

55

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1

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257

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Open Access Original Research

Downregulation of CRTAC1 in Urothelial Carcinoma Promotes Tumor Aggressiveness and Confers Poor Prognosis

Wei-Ming Li, Ti-Chun Chan, Yu-Ching Wei, Chien-Feng Li, ... Cheng-Fa Yeh

Front. Biosci. (Landmark Ed) 2023, 28(9), 217; https://doi.org/10.31083/j.fbl2809217

Abstract Full Text PDF(4.78MB)

82

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5

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355

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Open Access Original Research

Antiproliferative Activity of Lignans from Olea ferruginea: In Vitro Evidence Supported by Docking Studies

Abdur Rauf, Umer Rashid, Aniqa Atta, Ishaq Khan, ... Giovanni Ribaudo

Front. Biosci. (Landmark Ed) 2023, 28(9), 216; https://doi.org/10.31083/j.fbl2809216

Abstract Full Text PDF(561.25KB)

83

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7

Citations

313

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Open Access Original Research

EPO rs1617640 A>C is a Protective Factor for Chronic Obstructive Pulmonary Disease: A Case Control Study

Yunchao Wang, Zhi Li, Xiaoyi Zhang, Ao Lin, ... Xinhua Wang

Front. Biosci. (Landmark Ed) 2023, 28(9), 215; https://doi.org/10.31083/j.fbl2809215

Abstract Full Text PDF(1.52MB)

66

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1

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311

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Open Access Original Research

In Silico Identification of Therapeutic Targets and Novel Drug Candidates for Malignant Peripheral Nerve Sheath Tumors

Min Wei, Jianfeng Fan, Renjun Peng, Xiping Ding, ... He Huang

Front. Biosci. (Landmark Ed) 2023, 28(9), 214; https://doi.org/10.31083/j.fbl2809214

(This article belongs to the Special Issue Biomolecular identification of computational and statistical methods for Cancer and related diseases)

Abstract Full Text PDF(15.59MB)

72

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3

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253

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Open Access Original Research

The Effect of Aqueous Lessertia frutescens Extract on TM3 Leydig Cells Exposed to TNF-α in vitro

Kristian Leisegang, Renata Finelli, Ralf Henkel, Cătălina Zenoaga-Barbăroșie

Front. Biosci. (Landmark Ed) 2023, 28(9), 213; https://doi.org/10.31083/j.fbl2809213

(This article belongs to the Special Issue New Insights into the Quality of Sperm Cells)

Abstract Full Text PDF(1.53MB)

118

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1

Citations

295

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Open Access Original Research

SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2

Fei-Fei Luo, Jing Wang, Zhan-Fei Zhang, Si-Ting Lin, ... Bi-Jun Huang

Front. Biosci. (Landmark Ed) 2023, 28(9), 212; https://doi.org/10.31083/j.fbl2809212

Abstract Full Text PDF(5.71MB)

133

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3

Citations

464

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Open Access Review

The Role of Prohibitin-2 in Diseases

Fang Liu, You Zhang, Zhiyong Guo, An-Jing Ren

Front. Biosci. (Landmark Ed) 2023, 28(9), 211; https://doi.org/10.31083/j.fbl2809211

(This article belongs to the Special Issue Mitochondrial Biology in Health and Disease)

Abstract Full Text PDF(831.17KB)

264

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4

Citations

551

Views
Open Access Review

The Role of NLRP3 Inflammasomes in Trained Immunity

Gilyoung Lee, Huijeong Ahn, Eunsong Lee, Geun-Shik Lee

Front. Biosci. (Landmark Ed) 2023, 28(9), 210; https://doi.org/10.31083/j.fbl2809210

Abstract Full Text PDF(941.52KB)

292

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7

Citations

608

Views
Open Access Original Research

CD5L Deficiency Protects Mice Against Bleomycin-Induced Pulmonary Fibrosis

Yang Guo, Mengyan Zhu, Ruling Shen

Front. Biosci. (Landmark Ed) 2023, 28(9), 209; https://doi.org/10.31083/j.fbl2809209

Abstract Full Text PDF(9.65MB)

133

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3

Citations

362

Views
Open Access Review

Role of Ferroptosis in Glial Cells after Ischemic Stroke

Shu-Ying Xu, Si-Ming Ni, Chun-Li Zeng, Yong-Jun Peng

Front. Biosci. (Landmark Ed) 2023, 28(9), 208; https://doi.org/10.31083/j.fbl2809208

Abstract Full Text PDF(2.85MB)

165

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7

Citations

501

Views
Open Access Review

The Roles and Targeting of Tumor-Associated Macrophages

Yuqian Li, Ruoyao Wang, Qianqian Gao

Front. Biosci. (Landmark Ed) 2023, 28(9), 207; https://doi.org/10.31083/j.fbl2809207

Abstract Full Text PDF(4.55MB)

494

Downloads

13

Citations

693

Views
Open Access Review

Present Status and Advances in Chimeric Antigen Receptor T Cell Therapy for Glioblastoma

Shuchang Zhou, Han Sun, Sun Il Choi, Jinlong Yin

Front. Biosci. (Landmark Ed) 2023, 28(9), 206; https://doi.org/10.31083/j.fbl2809206

Abstract Full Text PDF(1.83MB)

224

Downloads

8

Citations

540

Views
Open Access Original Research

Zbtb14 Promotes Non-Alcoholic Fatty Liver Disease-Associated Fibrosis in Gerbils via the β-Catenin Pathway

Guocan Chen, Xiaobing Wang, Yongfen Zhu, Huiying Hu, Xiaofeng Chu

Front. Biosci. (Landmark Ed) 2023, 28(9), 205; https://doi.org/10.31083/j.fbl2809205

Abstract Full Text PDF(3.01MB)

90

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3

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345

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Open Access Review

From Mechanisms to Implications: Understanding the Molecular Neurotoxicity of Titanium Dioxide Nanoparticles

Michael Aschner, Anatoly V. Skalny, Abel Santamaria, Aleksandra Buha Djordjevic, ... Alexey A. Tinkov

Front. Biosci. (Landmark Ed) 2023, 28(9), 204; https://doi.org/10.31083/j.fbl2809204

(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

Abstract Full Text PDF(1.62MB)

192

Downloads

11

Citations

511

Views
Open Access Original Research

Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Alleviate Diabetic Kidney Disease in Rats by Inhibiting Apoptosis and Inflammation

Libo Liu, Yuquan Zhou, Xin Zhao, Xueyao Yang, ... Xiantao Song

Front. Biosci. (Landmark Ed) 2023, 28(9), 203; https://doi.org/10.31083/j.fbl2809203

Abstract Full Text PDF(6.29MB)

197

Downloads

15

Citations

660

Views
Open Access Original Research

Transcriptome Analysis Reveals Long Non-Coding RNAs Involved in Shade-Induced Growth Promotion in Pinellia ternata

Jinrong Yang, Wanning Cui, Qian You, Mengmeng Liu, ... Jianping Xue

Front. Biosci. (Landmark Ed) 2023, 28(9), 202; https://doi.org/10.31083/j.fbl2809202

Abstract Full Text PDF(2.69MB)

45

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7

Citations

270

Views
Open Access Original Research

CRISPR/Cas9-Targeted Mutagenesis of CiGAS and CiGAO to Reduce Bitterness in Chicory (Cichorium intybus L.)

Justine Domont, Margot Thiblet, Audrey Etienne, Harmony Alves Dos Santos, ... Caroline Rambaud

Front. Biosci. (Landmark Ed) 2023, 28(9), 201; https://doi.org/10.31083/j.fbl2809201

Abstract Full Text PDF(3.23MB)

197

Downloads

5

Citations

424

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Open Access Original Research

Yeast One-Hybrid Screening for Regulators of IbWD40 in Purple-Fleshed Sweet Potato (Ipomoea batatas [L] Lam.)

Danwen Fu, Rui Liu, Feng Gao

Front. Biosci. (Landmark Ed) 2023, 28(9), 200; https://doi.org/10.31083/j.fbl2809200

(This article belongs to the Special Issue Using Yeast Model in Molecular and Cell Biology)

Abstract Full Text PDF(9.26MB)

100

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2

Citations

348

Views
Open Access Original Research

N6-methyladenosine Methyltransferase METTL3 Enhances PTGER2 Expression to Increase Ovarian Cancer Stemness and Chemoresistance

Yi-Bin Lin, Ben-Hua Xu

Front. Biosci. (Landmark Ed) 2023, 28(9), 199; https://doi.org/10.31083/j.fbl2809199

(This article belongs to the Special Issue Diagnostic, Prognostic, and Therapeutic Biomarkers for Ovarian Cancer)

Abstract Full Text PDF(5.96MB)

118

Downloads

4

Citations

443

Views
Open Access Review

Potential Therapeutic Targets of Resveratrol in the Prevention and Treatment of Pulmonary Fibrosis

Iman Ramli, Thamere Cheriet, Anna Maria Posadino, Roberta Giordo, ... Gianfranco Pintus

Front. Biosci. (Landmark Ed) 2023, 28(9), 198; https://doi.org/10.31083/j.fbl2809198

(This article belongs to the Special Issue Inflammation and fibrosis: from molecular mechanisms to therapeutic opportunities)

Abstract Full Text PDF(6.20MB)

288

Downloads

25

Citations

791

Views
Open Access Review

Implications of Advances in Studies of O⁶-Methylguanine-DNA- Methyltransferase for Tumor Prognosis and Treatment

Yuexia Chen, Wei Qu, Jianhong Tu, Hongyan Qi

Front. Biosci. (Landmark Ed) 2023, 28(9), 197; https://doi.org/10.31083/j.fbl2809197

Abstract Full Text PDF(386.00KB)

183

Downloads

7

Citations

592

Views
Open Access Original Research

SHMT as a Potential Therapeutic Target for Renal Cell Carcinoma

Yongli Situ, Juying Zhang, Wenyu Liao, Quanyan Liang, ... Li Deng

Front. Biosci. (Landmark Ed) 2023, 28(9), 196; https://doi.org/10.31083/j.fbl2809196

Abstract Full Text PDF(37.70MB)

192

Downloads

6

Citations

674

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Open Access Original Research

Oridonin Synergistically Enhances the Pro-Apoptotic Effect of Venetoclax on Acute Myeloid Leukemia Cells by Inhibiting AKT Signaling

Lin Chen, Dongbei Li, Xiaoli Guo, Cheng Cheng, Xudong Wei

Front. Biosci. (Landmark Ed) 2023, 28(9), 195; https://doi.org/10.31083/j.fbl2809195

(This article belongs to the Special Issue Apoptosis in Cancer)

Abstract Full Text PDF(20.72MB)

173

Downloads

6

Citations

501

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Open Access Review

Epigenetic Mechanisms in Vascular Inflammation: Modulation of Endothelial Adhesion Molecules and Endothelium-Leukocyte Adhesion

Nadia Calabriso, Marika Massaro, Egeria Scoditti, Chiara Carluccio, ... Maria Annunziata Carluccio

Front. Biosci. (Landmark Ed) 2023, 28(9), 194; https://doi.org/10.31083/j.fbl2809194

Abstract Full Text PDF(1.62MB)

259

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18

Citations

617

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Open Access Original Research

Putative Cancer Stem Cell Markers are Frequently Expressed by Melanoma Cells in Vitro and in Situ but are also Present in Benign Differentiated Cells

Lisa Speigl, Nicole Janssen, Benjamin Weide, Tobias Sinnberg, ... Christopher Shipp

Front. Biosci. (Landmark Ed) 2023, 28(9), 193; https://doi.org/10.31083/j.fbl2809193

Abstract Full Text PDF(2.29MB)

66

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8

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406

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Front. Biosci. (Landmark Ed) Print ISSN 2768-6701 Electronic ISSN 2768-6698