Volume 28 Issue 11 2023

• Open Access Review

  The Roles of Long Noncoding RNA in Depression

  Sijian Wang, Lei Tang, Nanqi Huang, Hanyan Wang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 321; https://doi.org/10.31083/j.fbl2811321

  Abstract Full Text PDF(2.80MB)

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• Open Access Original Research

  Aspirin Inhibits Brain Metastasis of Lung Cancer via Upregulation of Tight Junction Protein Expression in Microvascular Endothelial Cells

  Dianfang Wei, Ming Tang, Weibo Gong, Jingshuo Liu, Lijuan Qin

  Front. Biosci. (Landmark Ed) 2023, 28(11), 320; https://doi.org/10.31083/j.fbl2811320

  Abstract Full Text PDF(2.50MB)

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  39

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• Open Access Original Research

  PEDF Prevents Mitochondrial Function Decay and ER Stress Induced by Rotenone in Aging RPE Cells

  Ruixue Zhang, Zhi Ji, Zhuoya Quan, Yao Lu, ... Yuan He

  Front. Biosci. (Landmark Ed) 2023, 28(11), 319; https://doi.org/10.31083/j.fbl2811319

  Abstract Full Text PDF(12.38MB)

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• Open Access Original Research

  MicroRNA-599-Regulated Susceptibility to Acute Kidney Injury in Patients with Cirrhosis is Mediated by the Sirtuin 1 (SIRT1) rs4746720 Single Nucleotide Polymorphism

  Fangfang Zhou, Yixin Chen, Youjun Xu, Qun Luo

  Front. Biosci. (Landmark Ed) 2023, 28(11), 318; https://doi.org/10.31083/j.fbl2811318

  Abstract Full Text PDF(1.59MB)

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• Open Access Review

  MicroRNA in Fibrotic Disorders: A Potential Target for Future Therapeutics

  Aanushka Mehjabin, Maliha Kabir, Luigina Micolucci, Most Mauluda Akhtar, ... Md Soriful Islam

  Front. Biosci. (Landmark Ed) 2023, 28(11), 317; https://doi.org/10.31083/j.fbl2811317

  (This article belongs to the Special Issue Inflammation and fibrosis: from molecular mechanisms to therapeutic opportunities)

  Abstract Full Text PDF(3.34MB)

  6

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• Open Access Original Research

  Silencing of CPNE1-TRAF2 Axis Restrains the Development of Pancreatic Cancer

  Yelin Song, Baolian Song, Zhichao Yu, Andong Li, ... Zuowei Li

  Front. Biosci. (Landmark Ed) 2023, 28(11), 316; https://doi.org/10.31083/j.fbl2811316

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(5.75MB)

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• Open Access Review

  Potential Role of GLP-1 Based Therapeutics in Coronary Artery Disease

  Qianfeng Xiong, Jing Wang, Kewen Huang, Wenbo Li, Lihui Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 315; https://doi.org/10.31083/j.fbl2811315

  Abstract Full Text PDF(267.05KB)

  6

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  59

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• Open Access Original Research

  Unveiling Circular RNA-Mediated Regulatory Mechanisms in Necroptosis in Premature Ovarian Failure

  Xin Jin, Wenjun Chen, Jiaxi Wang, Xianli Xu, ... Xuehua Feng

  Front. Biosci. (Landmark Ed) 2023, 28(11), 314; https://doi.org/10.31083/j.fbl2811314

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(17.04MB)

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• Open Access Original Research

  Hugan Buzure Granule Alleviates Acute Kidney Injury in Mice by Inhibiting NLRP3/Caspase-1 Pathway and TLR4/NF-κB Pathway

  Chongwang Ran, Bing Yu, Hailong Yin, Yanfang Yang, ... Qiang Yin

  Front. Biosci. (Landmark Ed) 2023, 28(11), 313; https://doi.org/10.31083/j.fbl2811313

  Abstract Full Text PDF(8.47MB)

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• Open Access Original Research

  Effect of Low-Dose Progesterone on Glycemic Metabolism, Morphology and Function of Adipose Tissue and Pancreatic Islets in Diet-Induced Obese Female Mice

  Matheus P. Santos, Leonardo F. R. Cauduro, Marilia Marcondes Ferreira, Luiz Felipe Martucci, ... Anna Karenina Azevedo-Martins

  Front. Biosci. (Landmark Ed) 2023, 28(11), 312; https://doi.org/10.31083/j.fbl2811312

  (This article belongs to the Special Issue Insulin resistance and cardiometabolic diseases: new perspective from basic to clinical research)

  Abstract Full Text PDF(1.23MB)

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• Open Access Original Research

  Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway

  Qing Zhu, Yuanshan Han, Ying He, Yilan Fu, ... Yingrui Shi

  Front. Biosci. (Landmark Ed) 2023, 28(11), 311; https://doi.org/10.31083/j.fbl2811311

  (This article belongs to the Special Issue Molecular Research for Breast Cancer)

  Abstract Full Text PDF(6.45MB)

  2

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• Open Access Original Research

  Effects of Radiotherapy and Chemotherapy on Platelet in Patients with Lung Cancer

  Shanshan Tang, Li Li, Shuanghu Yuan

  Front. Biosci. (Landmark Ed) 2023, 28(11), 310; https://doi.org/10.31083/j.fbl2811310

  Abstract Full Text PDF(4.84MB)

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• Open Access Original Research

  Gentiana Scabra Bge Extract (GSE) Protects Against Alcoholic Liver Disease by Regulating the TLR4/NF-κB Pathway in Mice

  Lijuan Wang, Yuxin Jiang, Qian Yu, Chunping Xiao, ... Ye Qiu

  Front. Biosci. (Landmark Ed) 2023, 28(11), 309; https://doi.org/10.31083/j.fbl2811309

  (This article belongs to the Special Issue Hepatotoxicity: Molecular Mechanisms and Pathophysiology)

  Abstract Full Text PDF(2.18MB)

  2

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• Open Access Original Research

  Prognostic and Immune Infiltration Signatures of GIMAP Family Genes in Clear Cell Renal Cell Carcinoma

  Mengjiao Zhang, Xu Zhang, Jing Hou, Xuemei Liang, Ming Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 308; https://doi.org/10.31083/j.fbl2811308

  (This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

  Abstract Full Text PDF(14.87MB)

  4

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  33

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• Open Access Review

  Differential Expression Patterns of Toll-like Receptors in COVID-19 Patients

  Nawon Lee, Ryeojin Ko, Soo Young Lee

  Front. Biosci. (Landmark Ed) 2023, 28(11), 307; https://doi.org/10.31083/j.fbl2811307

  (This article belongs to the Special Issue Toll-Like Receptors in Various Pathologies)

  Abstract Full Text PDF(1.37MB)

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• Open Access Original Research

  Serum Pentaxin 3 (PTX3) Promotes NLRP3 Inflammasome and Pyroptosis in Patients with Up-Regulated Myasthenia Gravis

  Yao Li, Shuhui Wang, Yunpeng Liu, Yongbo Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 306; https://doi.org/10.31083/j.fbl2811306

  (This article belongs to the Special Issue Inflammation and fibrosis: from molecular mechanisms to therapeutic opportunities)

  Abstract Full Text PDF(4.11MB)

  4

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• Open Access Review

  Advances in Bacterial Oligosaccharyltransferase Structure Elucidation and Potential Application to Glycoconjugate Vaccine Design

  Riye Lu, Pengwei Li, Li Zhu, Ming Xian Chang, Songying Ouyang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 305; https://doi.org/10.31083/j.fbl2811305

  Abstract Full Text PDF(2.96MB)

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• Open Access Original Research

  Integrated Single-Cell and Transcriptome Sequencing Analyses Develop a Ubiquitination-Associated Signature in Gastric Cancer and Identified OTULIN as a Novel Biomarker

  Zhongting Huang, Zhiyong Zhang, Yangyang Tu, Haibin He, ... Chunshu Pan

  Front. Biosci. (Landmark Ed) 2023, 28(11), 304; https://doi.org/10.31083/j.fbl2811304

  (This article belongs to the Special Issue Targeting Epigenetic Diseases Using Machine Learning Applications in Precision Medicine)

  Abstract Full Text PDF(10.24MB)

  14

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• Open Access Original Research

  Centrosomal Protein CEP135 Regulates the Migration and Angiogenesis of Endothelial Cells in a Microtubule-Dependent Manner

  Kun Wang, Xin Wang, Fayun Zhao, Qiang Zhao, ... Xuejun Zhang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 303; https://doi.org/10.31083/j.fbl2811303

  (This article belongs to the Special Issue New Frontiers in Vascular Remodeling)

  Abstract Full Text PDF(6.80MB)

  4

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  36

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• Open Access Review

  The Function, Underlying Mechanism and Clinical Potential of Exosomes in Colorectal Cancer

  Jinhong Han, Shuai Ma, Yao Zhao, Bingxian Wang, ... Yuhan Hu

  Front. Biosci. (Landmark Ed) 2023, 28(11), 302; https://doi.org/10.31083/j.fbl2811302

  Abstract Full Text PDF(7.21MB)

  2

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  44

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• Open Access Original Research

  The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer

  Xuan Zhang, Tao Wu, Rujia Qin, Xinyi Cai, ... Yunfeng Li

  Front. Biosci. (Landmark Ed) 2023, 28(11), 301; https://doi.org/10.31083/j.fbl2811301

  (This article belongs to the Special Issue Recent Advances in Cancer Research and Environmental Toxicology)

  Abstract Full Text PDF(14.15MB)

  11

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• Open Access Original Research

  Evaluation of N-Acetylmannosamine Administration to Restore Sialylation in GNE-Deficient Human Embryonal Kidney Cells

  Emilia Peters, Philipp Selke, Kaya Bork, Rüdiger Horstkorte, Astrid Gesper

  Front. Biosci. (Landmark Ed) 2023, 28(11), 300; https://doi.org/10.31083/j.fbl2811300

  Abstract Full Text PDF(6.09MB)

  6

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  26

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• Open Access Original Research

  Peripheral Blood Smears Distinguish Infective Fever after CAR-T Therapy

  Shaolong He, Juan Peng, Xingcheng Yang, Fankai Meng, ... Jia Wei

  Front. Biosci. (Landmark Ed) 2023, 28(11), 299; https://doi.org/10.31083/j.fbl2811299

  Abstract Full Text PDF(16.16MB)

  6

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  47

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• Open Access Original Research

  Chitosan-Based Conduits with Different Inner Diameters at both Ends Combined with Modified Formula Radix Hedysari Promote Nerve Transposition Repair

  Fengshi Zhang, Qicheng Li, Bo Ma, Meng Zhang, Yuhui Kou

  Front. Biosci. (Landmark Ed) 2023, 28(11), 298; https://doi.org/10.31083/j.fbl2811298

  (This article belongs to the Special Issue Biomaterials in Regenerative Medicine)

  Abstract Full Text PDF(2.84MB)

  5

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  24

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• Open Access Review

  The Functional Mechanisms of Toll-Like Receptor 3 and Its Implications in Digestive System Tumors

  Bin Han, Chao Zhang, Xiaoxiao Wang, Huangqin Song, ... Haoliang Zhao

  Front. Biosci. (Landmark Ed) 2023, 28(11), 297; https://doi.org/10.31083/j.fbl2811297

  Abstract Full Text PDF(2.28MB)

  11

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• Open Access Original Research

  Oxidative Stress Levels and DNA Repair Kinetics in Senescent Primary Human Fibroblasts Exposed to Chronic Low Dose Rate of Ionizing Radiation

  Traimate Sangsuwan, Ali Pour Khavari, Evelina Blomberg, Tajanena Romell, ... Siamak Haghdoost

  Front. Biosci. (Landmark Ed) 2023, 28(11), 296; https://doi.org/10.31083/j.fbl2811296

  (This article belongs to the Special Issue Influence of Radiation Quality on Cellular, Molecular and Inflammatory Responses in Normal and Malignant Human Cells)

  Abstract Full Text PDF(6.67MB)

  12

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• Open Access Original Research

  High Norepinephrine State Induces Growth of Colorectal Cancer Cells via ADP-Ribosyltransferase 1 in Type 2 Diabetes Mellitus

  Wenwen Chen, Hailun Xie, Ming Xiao, Ming Li, ... Yalan Wang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 295; https://doi.org/10.31083/j.fbl2811295

  Abstract Full Text PDF(3.06MB)

  7

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  62

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• Open Access Original Research

  Ubiquitin C-Terminal Hydrolase L5 Plays an Essential Role in the Fly Innate Immune Defense against Bacterial Infection

  Chao Zhang, Shikun Zhang, Fanrui Kong, Yihua Xiao, ... Yongzhi Hua

  Front. Biosci. (Landmark Ed) 2023, 28(11), 294; https://doi.org/10.31083/j.fbl2811294

  Abstract Full Text PDF(2.82MB)

  8

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• Open Access Original Research

  Bioinformatic Identification of the Pyroptosis-Related Transcription Factor-MicroRNA-Target Gene Regulatory Network in Angiotensin II-Induced Cardiac Remodeling and Validation of Key Components

  Tiejun Huang, Jieqiong Ding, Li Lin, Lu Han, ... Mincai Li

  Front. Biosci. (Landmark Ed) 2023, 28(11), 293; https://doi.org/10.31083/j.fbl2811293

  Abstract Full Text PDF(16.36MB)

  9

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  47

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• Open Access Original Research

  1-L Transcription in Parkinson's Disease

  Jozef Nahalka

  Front. Biosci. (Landmark Ed) 2023, 28(11), 292; https://doi.org/10.31083/j.fbl2811292

  (This article belongs to the Special Issue Thinking about RNA-Binding Proteins: Emerging Roles in Human Health and Diseases)

  Abstract Full Text PDF(4.32MB)

  10

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• Open Access Original Research

  Characteristics of Electroacupuncture Preconditioning and Treatment on Regulation of the Brain Transcriptome in Rats with Ischemic Stroke

  Shuping Fu, Bufan Wu, Rou Peng, Houxi Xu, ... Shengfeng Lu

  Front. Biosci. (Landmark Ed) 2023, 28(11), 291; https://doi.org/10.31083/j.fbl2811291

  Abstract Full Text PDF(27.65MB)

  18

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  110

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• Open Access Original Research

  Structural Composition and Diversity of Bacterial Communities in High- and Low-Yielding Moso Bamboo Forests

  Zongsheng Yuan, Fang Liu, Yue Yuan, Hui Pan

  Front. Biosci. (Landmark Ed) 2023, 28(11), 290; https://doi.org/10.31083/j.fbl2811290

  (This article belongs to the Special Issue Endophytic Bacteria: Microbial Ecology, Genomic Analysis and Biotechnological Applications)

  Abstract Full Text PDF(4.74MB)

  15

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  50

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• Open Access Original Research

  Comprehensive Analysis of Regulated Cell Death in Intracranial Aneurysms

  Jianyu Zhu, Zhicheng Wang, Jiebo Li, Dezhi Kang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 289; https://doi.org/10.31083/j.fbl2811289

  Abstract Full Text PDF(10.92MB)

  9

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• Open Access Original Research

  Identification of Potential Inhibitors Targeting GTPase-Kirsten RAt Sarcoma Virus (K-Ras) Driven Cancers via E-Pharmacophore-Based Virtual Screening and Drug Repurposing Approach

  Udhaya Kumar. S, Rinku Polachirakkal Varghese, V. Anu Preethi, C. George Priya Doss, Hatem Zayed

  Front. Biosci. (Landmark Ed) 2023, 28(11), 288; https://doi.org/10.31083/j.fbl2811288

  (This article belongs to the Special Issue New Targets in Anticancer Therapy)

  Abstract Full Text PDF(4.04MB)

  14

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• Open Access Original Research

  Anoikis Patterns in Cervical Cancer: Identification of Subgroups and Construction of a Novel Risk Model for Predicting Prognosis and Immune Response

  Xuesong Xiang, Jingxin Ding

  Front. Biosci. (Landmark Ed) 2023, 28(11), 287; https://doi.org/10.31083/j.fbl2811287

  (This article belongs to the Special Issue Targeting Epigenetic Diseases Using Machine Learning Applications in Precision Medicine)

  Abstract Full Text PDF(12.78MB)

  27

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  121

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• Open Access Review

  Insights into the Role of Oxidative Stress in Hepatocellular Carcinoma Development

  Yuanyuan Li, Yang Yu, Lei Yang, Rui Wang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 286; https://doi.org/10.31083/j.fbl2811286

  (This article belongs to the Special Issue Oxidative Stress in Cancer)

  Abstract Full Text PDF(2.33MB)

  19

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  96

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• Open Access Review

  Preconditioning of Mesenchymal Stem Cells with Electromagnetic Fields and Its Impact on Biological Responses and “Fate”—Potential Use in Therapeutic Applications

  Anna Sendera, Barbara Pikuła, Agnieszka Banaś-Ząbczyk

  Front. Biosci. (Landmark Ed) 2023, 28(11), 285; https://doi.org/10.31083/j.fbl2811285

  (This article belongs to the Special Issue Adipose Stem Cell Biology)

  Abstract Full Text PDF(1011.89KB)

  22

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  88

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• Open Access Original Research

  Identification of Whole-Blood DNA Methylation Signatures and Rules Associated with COVID-19 Severity

  Fei Yuan, JingXin Ren, HuiPing Liao, Wei Guo, ... Yu-Dong Cai

  Front. Biosci. (Landmark Ed) 2023, 28(11), 284; https://doi.org/10.31083/j.fbl2811284

  Abstract Full Text PDF(2.29MB)

  13

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  57

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• Open Access Original Research

  Differential Expression Analysis Based on Ensemble Strategy on miRNA Profiles of Kidney Clear Cell Carcinoma

  Enyang Zhao, Ziqi Xi, Qiong Wu

  Front. Biosci. (Landmark Ed) 2023, 28(11), 283; https://doi.org/10.31083/j.fbl2811283

  Abstract Full Text PDF(6.03MB)

  14

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• Open Access Original Research

  Endothelial Progenitor-Cell-Derived Exosomes Induced by Astragaloside IV Accelerate Type I Diabetic-wound Healing via the PI3K/AKT/mTOR Pathway in Rats

  Wu Xiong, Xue Bai, Xi Zhang, Huajuan Lei, ... Xiaoling Zou

  Front. Biosci. (Landmark Ed) 2023, 28(11), 282; https://doi.org/10.31083/j.fbl2811282

  (This article belongs to the Special Issue Plant Bioactive Molecules)

  Abstract Full Text PDF(10.11MB)

  12

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  86

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• Open Access Systematic Review

  The Effect of High-Intensity Interval Training on Mitochondrial-Associated Indices in Overweight and Obese Adults: A Systematic Review and Meta-Analysis

  Spyridon Hadjispyrou, Petros C Dinas, Spyridon Marios Delitheos, Ioannis-Alexios Koumprentziotis, ... Anastassios Philippou

  Front. Biosci. (Landmark Ed) 2023, 28(11), 281; https://doi.org/10.31083/j.fbl2811281

  (This article belongs to the Special Issue Mitochondrial Dysfunction and Myopathies)

  Abstract Full Text PDF(1.53MB)

  28

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  106

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• Open Access Original Research

  Six Transmembrane Epithelial Antigen 1 as a Prognostic Biomarker in Carcinomas: A Meta-Analysis

  Shidi Zhao, Huan Chen, Yan Zhou, Quanfang Wang, ... Jin Yang

  Front. Biosci. (Landmark Ed) 2023, 28(11), 280; https://doi.org/10.31083/j.fbl2811280

  (This article belongs to the Special Issue Mechanisms of Control and Inhibition of Genes in Most Aggressive Tumors: Pathways, Targets and Treatments)

  Abstract Full Text PDF(3.68MB)

  19

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  83

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• Open Access Original Research

  Rubus suavissimus S. Lee Extract Alleviates Oxidative Stress and Inflammation in H₂O₂-Treated Retinal Pigment Epithelial Cells and in High-Fat Diet-Fed Mouse Retinas

  Minzhuo Liu, Shuiqing Wu, Yi Wu, Jie Zhang, ... Zhihong Zeng

  Front. Biosci. (Landmark Ed) 2023, 28(11), 279; https://doi.org/10.31083/j.fbl2811279

  Abstract Full Text PDF(6.32MB)

  18

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  64

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• Open Access Original Research

  Site-Specific Profiling of N-Glycans in Drosophila melanogaster

  Fei Zhao, Chenyu Jia, Fangyu He, Meiting Hu, ... Xuesong Feng

  Front. Biosci. (Landmark Ed) 2023, 28(11), 278; https://doi.org/10.31083/j.fbl2811278

  Abstract Full Text PDF(4.52MB)

  9

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• Open Access Original Research

  Inhibition of PFKFB3 Expression Stimulates Macrophage-Mediated Lymphangiogenesis Post-Acute Myocardial Infarction

  Tianyi Cui, Chao Feng, Hantao Jiang, Ying Jin, Jinping Feng

  Front. Biosci. (Landmark Ed) 2023, 28(11), 277; https://doi.org/10.31083/j.fbl2811277

  (This article belongs to the Special Issue Myocardial Ischaemia–Reperfusion Injury)

  Abstract Full Text PDF(11.55MB)

  19

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