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Volume 31, Issue 4 (April 2026)
Effect of Endogenous FGF21 Deficiency on the Inflammatory Microenvironment of the Retina
Front. Biosci. (Landmark Ed) 2026, 31(4), 47702; https://doi.org/10.31083/FBL47702
Context-Dependent Modulation of Macrophage Plasticity by Cordycepin Drives Tumor Regression in Melanoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 52067; https://doi.org/10.31083/FBL52067
Retraction: Li et al. MEG3 Targets miR-184 and Wnt/β-catenin and Modulates Properties of Osteosarcoma. Frontiers in Bioscience (Landmark Edition). 2020; 25: 1901–1912
Front. Biosci. (Landmark Ed) 2026, 31(4), 53323; https://doi.org/10.31083/FBL53323
Calcitonin Receptor is a Novel Biomarker for NF-κB-Mediated Cellular Stress in Triple-Negative Breast Cancer Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 50148; https://doi.org/10.31083/FBL50148
Rosuvastatin Ameliorates the Initiation and Progression of Lung Adenocarcinoma via Facilitating PLK1 Inhibition
Front. Biosci. (Landmark Ed) 2026, 31(4), 49156; https://doi.org/10.31083/FBL49156
ApoA-I Dissociated From Human HDL Retains its Acceptor Properties in ABCA1-mediated Cholesterol Efflux From RAW 264.7 Macrophages in Coronary Artery Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 50403; https://doi.org/10.31083/FBL50403
Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration
Front. Biosci. (Landmark Ed) 2026, 31(4), 49564; https://doi.org/10.31083/FBL49564
Annexin A5 Regulates Store-Operated Calcium Entry via Glyceraldehyde-3-Phosphate Dehydrogenase in Hepatocellular Carcinoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 49504; https://doi.org/10.31083/FBL49504
Gender Differences in the Effects of Esomeprazole on Ethanol-Induced Acute Gastric Injury in Mice
Front. Biosci. (Landmark Ed) 2026, 31(4), 49148; https://doi.org/10.31083/FBL49148
The Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle–Mediated Tissue Repair After Spinal Cord Injury
Front. Biosci. (Landmark Ed) 2026, 31(4), 47612; https://doi.org/10.31083/FBL47612
Shionone Alleviates Sepsis-Induced Acute Lung Injury by Regulating Macrophage Polarization Through the HMGB1/NF-κB Pathway
Front. Biosci. (Landmark Ed) 2026, 31(4), 49062; https://doi.org/10.31083/FBL49062
Enhancer of Zeste Homologue 2 Promotes Vascular Calcification Associated With Chronic Kidney Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 48723; https://doi.org/10.31083/FBL48723
Inactivation of NONO by Auranofin or RNA Interference Triggers Lethal Oxidative Stress in Neuroblastoma Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 48544; https://doi.org/10.31083/FBL48544
(This article belongs to the Special Issue Molecular and Cellular Mechanisms in High-Risk and Progressive Neuroblastoma)
ADAM8 Deficiency in Macrophages Alleviates Vascular Calcification in Chronic Kidney Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 49495; https://doi.org/10.31083/FBL49495
Metagenomic Analysis Reveals Gut Microbiota Features in Membranous Nephropathy
Front. Biosci. (Landmark Ed) 2026, 31(4), 48982; https://doi.org/10.31083/FBL48982
The Gut–Lung Axis, Epigenetics and Respiratory Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 48743; https://doi.org/10.31083/FBL48743
Artificial Intelligence and Vitamin D Deficiency: Opportunities and Challenges for Clinical Translation in Chronic Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 50946; https://doi.org/10.31083/FBL50946
Emodin Alleviates Lipid Accumulation and Renal Tubular Injury in Rats With DN via Inhibiting HIF-1α Expression
Front. Biosci. (Landmark Ed) 2026, 31(4), 49862; https://doi.org/10.31083/FBL49862
Multi-Dimensional Data Integration Reveals the Molecular Mechanism of Metabolic Reprogramming Associated With Low Asparaginase Expression in Hepatocellular Carcinoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 49215; https://doi.org/10.31083/FBL49215
Potential Application of HIF-PH Inhibitors to Treat Kidney Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 47718; https://doi.org/10.31083/FBL47718
CD44+ and CD133+ Extracellular Vesicles as Future Potential Targets in Gastrointestinal Tumor
Front. Biosci. (Landmark Ed) 2026, 31(4), 46312; https://doi.org/10.31083/FBL46312
Demethylase ALKBH4 Inhibits Cell Proliferation via Induction of 5′-tsRNAGlu in Non-Small Cell Lung Cancer
Front. Biosci. (Landmark Ed) 2026, 31(4), 50109; https://doi.org/10.31083/FBL50109
Ameliorative Effect of Luteolin on H2O2-Induced Mitophagy and Apoptosis in Cardiomyocytes Through Modulation of the AMPK/mTOR Pathway
Front. Biosci. (Landmark Ed) 2026, 31(4), 50047; https://doi.org/10.31083/FBL50047
Feature of NETosis in Chronic Granulomatous Disease and Its Impact on Renal Disorder
Front. Biosci. (Landmark Ed) 2026, 31(4), 47594; https://doi.org/10.31083/FBL47594
Ferroptosis in Breast Cancer: Molecular Insights and Therapeutic Strategies
Front. Biosci. (Landmark Ed) 2026, 31(4), 50950; https://doi.org/10.31083/FBL50950
A Stage IA and IB Endometrial Cancer Classification Method Using Genetic Programming on MRI Images
Front. Biosci. (Landmark Ed) 2026, 31(4), 49257; https://doi.org/10.31083/FBL49257
An Emerging Approach to IBD Treatment: Personalized Nutrition Through Gut Microbiome Optimization
Front. Biosci. (Landmark Ed) 2026, 31(4), 47779; https://doi.org/10.31083/FBL47779
Keap1-Nrf2 Signaling Pathway-Mediated Antioxidant Defense in Neurodegenerative Diseases: Mechanisms and Traditional Chinese Medicine Therapeutic Strategies
Front. Biosci. (Landmark Ed) 2026, 31(4), 45233; https://doi.org/10.31083/FBL45233
(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions of Neurological and Neuropsychiatric Disorders - Volume 2)
NDRG2 Drives DRP1 Phosphorylation to Promote the Progression of Pulmonary Hypertension
Front. Biosci. (Landmark Ed) 2026, 31(4), 48054; https://doi.org/10.31083/FBL48054
Computational Pathology as a Mechanistic Discipline: From Morphology to Molecular Data
Front. Biosci. (Landmark Ed) 2026, 31(4), 47914; https://doi.org/10.31083/FBL47914
(This article belongs to the Special Issue Machine Learning in Molecular Biology)
Hypoxic Regulation of Notch1 Promotes Mitochondrial Fission and Scleral Remodeling in Myopia
Front. Biosci. (Landmark Ed) 2026, 31(4), 49381; https://doi.org/10.31083/FBL49381
From Normal Mucosa to Colorectal Cancer in Lynch Syndrome: Single-Cell Dissection of Cellular Heterogeneity and Communication Networks
Front. Biosci. (Landmark Ed) 2026, 31(4), 47730; https://doi.org/10.31083/FBL47730
Quercetin Enhances the Antitumor Effect of Lenvatinib on Hepatocellular Carcinoma Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 47715; https://doi.org/10.31083/FBL47715
Discovering the Hidden Power of NGLY1: Orchestrating Immune Cell Functions and Autoimmune Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 46961; https://doi.org/10.31083/FBL46961
(This article belongs to the Special Issue Cellular and Molecular Study in Immunopharmacology)
Roles of AKR1C1 in Non-small Cell Lung Cancer
Front. Biosci. (Landmark Ed) 2026, 31(4), 45736; https://doi.org/10.31083/FBL45736
Establishment of a Novel IDH1 wild type Glioblastoma Cell Line, SHG142, and Its Organoids
Front. Biosci. (Landmark Ed) 2026, 31(4), 49045; https://doi.org/10.31083/FBL49045
Volume 31, Issue 4 (2026)

Journal Browser
Forthcoming Issue
Current Issue
Article
Effect of Endogenous FGF21 Deficiency on the Inflammatory Microenvironment of the Retina
Front. Biosci. (Landmark Ed) 2026, 31(4), 47702; https://doi.org/10.31083/FBL47702
Context-Dependent Modulation of Macrophage Plasticity by Cordycepin Drives Tumor Regression in Melanoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 52067; https://doi.org/10.31083/FBL52067
Retraction: Li et al. MEG3 Targets miR-184 and Wnt/β-catenin and Modulates Properties of Osteosarcoma. Frontiers in Bioscience (Landmark Edition). 2020; 25: 1901–1912
Front. Biosci. (Landmark Ed) 2026, 31(4), 53323; https://doi.org/10.31083/FBL53323
Calcitonin Receptor is a Novel Biomarker for NF-κB-Mediated Cellular Stress in Triple-Negative Breast Cancer Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 50148; https://doi.org/10.31083/FBL50148
Rosuvastatin Ameliorates the Initiation and Progression of Lung Adenocarcinoma via Facilitating PLK1 Inhibition
Front. Biosci. (Landmark Ed) 2026, 31(4), 49156; https://doi.org/10.31083/FBL49156
ApoA-I Dissociated From Human HDL Retains its Acceptor Properties in ABCA1-mediated Cholesterol Efflux From RAW 264.7 Macrophages in Coronary Artery Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 50403; https://doi.org/10.31083/FBL50403
Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration
Front. Biosci. (Landmark Ed) 2026, 31(4), 49564; https://doi.org/10.31083/FBL49564
Annexin A5 Regulates Store-Operated Calcium Entry via Glyceraldehyde-3-Phosphate Dehydrogenase in Hepatocellular Carcinoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 49504; https://doi.org/10.31083/FBL49504
Gender Differences in the Effects of Esomeprazole on Ethanol-Induced Acute Gastric Injury in Mice
Front. Biosci. (Landmark Ed) 2026, 31(4), 49148; https://doi.org/10.31083/FBL49148
The Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle–Mediated Tissue Repair After Spinal Cord Injury
Front. Biosci. (Landmark Ed) 2026, 31(4), 47612; https://doi.org/10.31083/FBL47612
Shionone Alleviates Sepsis-Induced Acute Lung Injury by Regulating Macrophage Polarization Through the HMGB1/NF-κB Pathway
Front. Biosci. (Landmark Ed) 2026, 31(4), 49062; https://doi.org/10.31083/FBL49062
Enhancer of Zeste Homologue 2 Promotes Vascular Calcification Associated With Chronic Kidney Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 48723; https://doi.org/10.31083/FBL48723
Inactivation of NONO by Auranofin or RNA Interference Triggers Lethal Oxidative Stress in Neuroblastoma Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 48544; https://doi.org/10.31083/FBL48544
(This article belongs to the Special Issue Molecular and Cellular Mechanisms in High-Risk and Progressive Neuroblastoma)
ADAM8 Deficiency in Macrophages Alleviates Vascular Calcification in Chronic Kidney Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 49495; https://doi.org/10.31083/FBL49495
Metagenomic Analysis Reveals Gut Microbiota Features in Membranous Nephropathy
Front. Biosci. (Landmark Ed) 2026, 31(4), 48982; https://doi.org/10.31083/FBL48982
The Gut–Lung Axis, Epigenetics and Respiratory Disease
Front. Biosci. (Landmark Ed) 2026, 31(4), 48743; https://doi.org/10.31083/FBL48743
Artificial Intelligence and Vitamin D Deficiency: Opportunities and Challenges for Clinical Translation in Chronic Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 50946; https://doi.org/10.31083/FBL50946
Emodin Alleviates Lipid Accumulation and Renal Tubular Injury in Rats With DN via Inhibiting HIF-1α Expression
Front. Biosci. (Landmark Ed) 2026, 31(4), 49862; https://doi.org/10.31083/FBL49862
Multi-Dimensional Data Integration Reveals the Molecular Mechanism of Metabolic Reprogramming Associated With Low Asparaginase Expression in Hepatocellular Carcinoma
Front. Biosci. (Landmark Ed) 2026, 31(4), 49215; https://doi.org/10.31083/FBL49215
Potential Application of HIF-PH Inhibitors to Treat Kidney Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 47718; https://doi.org/10.31083/FBL47718
CD44+ and CD133+ Extracellular Vesicles as Future Potential Targets in Gastrointestinal Tumor
Front. Biosci. (Landmark Ed) 2026, 31(4), 46312; https://doi.org/10.31083/FBL46312
Demethylase ALKBH4 Inhibits Cell Proliferation via Induction of 5′-tsRNAGlu in Non-Small Cell Lung Cancer
Front. Biosci. (Landmark Ed) 2026, 31(4), 50109; https://doi.org/10.31083/FBL50109
Ameliorative Effect of Luteolin on H2O2-Induced Mitophagy and Apoptosis in Cardiomyocytes Through Modulation of the AMPK/mTOR Pathway
Front. Biosci. (Landmark Ed) 2026, 31(4), 50047; https://doi.org/10.31083/FBL50047
Feature of NETosis in Chronic Granulomatous Disease and Its Impact on Renal Disorder
Front. Biosci. (Landmark Ed) 2026, 31(4), 47594; https://doi.org/10.31083/FBL47594
Ferroptosis in Breast Cancer: Molecular Insights and Therapeutic Strategies
Front. Biosci. (Landmark Ed) 2026, 31(4), 50950; https://doi.org/10.31083/FBL50950
A Stage IA and IB Endometrial Cancer Classification Method Using Genetic Programming on MRI Images
Front. Biosci. (Landmark Ed) 2026, 31(4), 49257; https://doi.org/10.31083/FBL49257
An Emerging Approach to IBD Treatment: Personalized Nutrition Through Gut Microbiome Optimization
Front. Biosci. (Landmark Ed) 2026, 31(4), 47779; https://doi.org/10.31083/FBL47779
Keap1-Nrf2 Signaling Pathway-Mediated Antioxidant Defense in Neurodegenerative Diseases: Mechanisms and Traditional Chinese Medicine Therapeutic Strategies
Front. Biosci. (Landmark Ed) 2026, 31(4), 45233; https://doi.org/10.31083/FBL45233
(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions of Neurological and Neuropsychiatric Disorders - Volume 2)
NDRG2 Drives DRP1 Phosphorylation to Promote the Progression of Pulmonary Hypertension
Front. Biosci. (Landmark Ed) 2026, 31(4), 48054; https://doi.org/10.31083/FBL48054
Computational Pathology as a Mechanistic Discipline: From Morphology to Molecular Data
Front. Biosci. (Landmark Ed) 2026, 31(4), 47914; https://doi.org/10.31083/FBL47914
(This article belongs to the Special Issue Machine Learning in Molecular Biology)
Hypoxic Regulation of Notch1 Promotes Mitochondrial Fission and Scleral Remodeling in Myopia
Front. Biosci. (Landmark Ed) 2026, 31(4), 49381; https://doi.org/10.31083/FBL49381
From Normal Mucosa to Colorectal Cancer in Lynch Syndrome: Single-Cell Dissection of Cellular Heterogeneity and Communication Networks
Front. Biosci. (Landmark Ed) 2026, 31(4), 47730; https://doi.org/10.31083/FBL47730
Quercetin Enhances the Antitumor Effect of Lenvatinib on Hepatocellular Carcinoma Cells
Front. Biosci. (Landmark Ed) 2026, 31(4), 47715; https://doi.org/10.31083/FBL47715
Discovering the Hidden Power of NGLY1: Orchestrating Immune Cell Functions and Autoimmune Diseases
Front. Biosci. (Landmark Ed) 2026, 31(4), 46961; https://doi.org/10.31083/FBL46961
(This article belongs to the Special Issue Cellular and Molecular Study in Immunopharmacology)
Roles of AKR1C1 in Non-small Cell Lung Cancer
Front. Biosci. (Landmark Ed) 2026, 31(4), 45736; https://doi.org/10.31083/FBL45736
Establishment of a Novel IDH1 wild type Glioblastoma Cell Line, SHG142, and Its Organoids
Front. Biosci. (Landmark Ed) 2026, 31(4), 49045; https://doi.org/10.31083/FBL49045
