Identification of as a Key Biomarker for Ferroptosis Resistance and Immunotherapy Response in Bladder Cancer via Multi-Omics Integration and Machine Learning

Jianyuan Lei, Ping Wang, Yanchun Qu, Xingfen Wang, Xianglian Zhang, Hui Li, Pengyu Zhang

Front. Biosci. (Landmark Ed) 2025, 30(9), 44395; https://doi.org/10.31083/FBL44395

Single-cell Analyses Highlight the Proinflammatory Contribution of Low-density Neutrophils in the Acute Phase of Severe Fever With Thrombocytopenia Syndrome

Jiaying Zhao, Chunhui Wang, Ke Jin, Yan Dai, Yaqin Zhang, Tingting Zhou, Zhan Yang, Tao Yang, Yuan Liu, Nannan Hu, Yinghua Mao, Chuanlong Zhu, Ping Shi, Xuewei Sun, Jin Zhu, Jun Li

Front. Biosci. (Landmark Ed) 2025, 30(9), 40723; https://doi.org/10.31083/FBL40723

Astrocytic Biomarkers in Epilepsy: A Critical Review on Clinical Utility and Mechanistic Implications

Ting-Rong Hsu, Pei-Hao Chen, Wei-Sheng Lin

Front. Biosci. (Landmark Ed) 2025, 30(9), 39022; https://doi.org/10.31083/FBL39022

Inhibition of S100A9 Improves Aortic Dissection in Association With Mitochondrial Function Enhancement

Keyu Zhang, Linman Li, Yiying Zhang, Kai Guo, Zhao Zhang, Mengning Wan, Yongzheng Guo, Yu Zhao, Xiaowen Wang

Front. Biosci. (Landmark Ed) 2025, 30(9), 44666; https://doi.org/10.31083/FBL44666

Transcriptional Dysregulation of Autophagy in Aging and Potential Interventions: Insights Into TFEB and FOXOs

Cheng-Ju Kuo, Denisa M. Manastireanu, Jose L. Nieto-Torres, Caroline Kumsta

Front. Biosci. (Landmark Ed) 2025, 30(9), 38730; https://doi.org/10.31083/FBL38730

Single-cell Transcriptome Analysis Reveals the Potential Role of Hepatic Stellate Cells in Liver Fibrosis

Xiaoling Wang, Ying Wang, Meng Yang, Taoran Zhao, Zhiwei Feng, Yujie Zhou, Xuewei Li, Yuanhao Yang, Zhizhen Liu, Guoping Zheng, Jun Xie

Front. Biosci. (Landmark Ed) 2025, 30(9), 42394; https://doi.org/10.31083/FBL42394

Fto-Mediated m6A Demethylation of Anxa1 Attenuates Cardiac Ischemia–Reperfusion Injury With Suppression of Nlrp3 Inflammasome Signals

Chaojie He, Haojie Yang, Lijia Xu, Hao Zhang, Huilin Hu

Front. Biosci. (Landmark Ed) 2025, 30(9), 42765; https://doi.org/10.31083/FBL42765

Unconjugated Bile Acids and Alcohols Inhibit Degranulation of Stimulated RBL-2H3 Cells

Michiko Yoshii, Ai Tarao, Yasuko Ichinose, Naomi Iwasa, Fumi Tanaka, Yuhki Yanase, Koichiro Ozawa

Front. Biosci. (Landmark Ed) 2025, 30(9), 44504; https://doi.org/10.31083/FBL44504

Short Overview on the Involvement of Lipid Peroxidation Product 4-Hydroxynonenal in Diverse Pathways of Cell Death

Morana Jaganjac, Anita Stojanovic Markovic, Nicola Deiana, Neven Zarkovic

Front. Biosci. (Landmark Ed) 2025, 30(9), 37139; https://doi.org/10.31083/FBL37139

PTDSS1 Drives Glycolysis and Malignant Progression of Lung Cancer Through Maintaining Nuclear–Mitochondrial Homeostatic Crosstalk

Hailun Wang, Qiao Wang, Yandu He, Xuelu Pu, Yajun Li

Front. Biosci. (Landmark Ed) 2025, 30(9), 45020; https://doi.org/10.31083/FBL45020

Single-cell Sequencing Analysis Reveals Cell Subtypes With High Expression of Coagulation Factor 3 and Their Possible Roles in Pancreatic Ductal Adenocarcinoma

Chunyan Wang, Chanjuan Cui, Shengkai Huang, Mengyao Yu, Lili Wang, Hengwen Gong, Rui Qiao, Jun Ma

Front. Biosci. (Landmark Ed) 2025, 30(9), 44029; https://doi.org/10.31083/FBL44029

Colchicine Only Inhibits in Higher Doses Hyperactivated NLRP3 Inflammasome—The Main Respondent for Complications in COVID-19 and Influenza

Vanyo Mitev, Georgi Momekov

Front. Biosci. (Landmark Ed) 2025, 30(9), 44744; https://doi.org/10.31083/FBL44744

Modulation of Mitochondrial Dynamics in Primary Hippocampal Cultures of 5xFAD Mice by Mdivi-1, MFP, and Exogenous Zinc

Alina Chaplygina, Daria Zhdanova

Front. Biosci. (Landmark Ed) 2025, 30(9), 44648; https://doi.org/10.31083/FBL44648

Excavation of Molecular Subtypes of Cervical Cancer Based on DNA Methylation Patterns

Yiwei Zhao, Chutong Zhao, Jiyun Zhao, Yuhan Ma, Shunjin Zhang, Yujie Liu, Yuan Wang, Sijia Liu, Yunyan Zhang

Front. Biosci. (Landmark Ed) 2025, 30(9), 45025; https://doi.org/10.31083/FBL45025

(This article belongs to the Special Issue Molecular Mechanisms in Reproductive Cancers)

Advances in Single-Cell RNA Sequencing: Applications and Mechanistic Insights in Haematopoietic Malignancies

Yixin Guo, Shuang Wang, Xinyue Huang, Yanhua Zheng, Fang Liu, Xiaoxue Wang

Front. Biosci. (Landmark Ed) 2025, 30(9), 39064; https://doi.org/10.31083/FBL39064

Diagnostic Value of Promoter Methylation in Lung Cancer via Liquid Biopsy: A Systematic Review and Meta-Analysis

Yuheng Yan, Ziyang Xu, Fangfang Liu, Yuhan Jia, Qian Chu, Xun Yuan

Front. Biosci. (Landmark Ed) 2025, 30(9), 43987; https://doi.org/10.31083/FBL43987

Integrated Analysis of Single-cell and Bulk-RNA Sequencing Data to Identify Redox-related Genes as Prognostic Biomarkers and Therapeutic Targets of Lung Adenocarcinoma With Osimertinib Resistance

Chen Fang, Chaoxing Liu, Rong Qi, Jiabin Ding, Ting Luo, Feng Yu, Guohua Zhang, Chao Shi, Daya Luo, Feng Qiu

Front. Biosci. (Landmark Ed) 2025, 30(9), 40454; https://doi.org/10.31083/FBL40454

Notch1 Inhibition Exacerbates APAP-Induced Liver Injury via β-Catenin and Macrophage Polarization

Tao Yang, Jingjing Dai, Junlan Zhou, Yuyun Shao, Xiao Wang, Jiaying Zhao, Jun Li, Ping Shi, Longfeng Jiang

Front. Biosci. (Landmark Ed) 2025, 30(9), 43853; https://doi.org/10.31083/FBL43853

(This article belongs to the Special Issue Cellular and Molecular Study in Immunopharmacology)

Cystine and Antibiotic Treatment Alters Low Molecular Weight Thiol Levels in

Galina Smirnova, Aleksey Tyulenev, Tatyana Kalashnikova, Lyubov Sutormina, Vadim Ushakov, Oleg Oktyabrsky

Front. Biosci. (Landmark Ed) 2025, 30(9), 44441; https://doi.org/10.31083/FBL44441

The Potential of Macrophages for Skin Anti-aging

Hang Zhou, Yun Wang, Yu-Mei Li, Yun-Wen Zheng

Front. Biosci. (Landmark Ed) 2025, 30(9), 38891; https://doi.org/10.31083/FBL38891

Argon Alleviates Bone Cancer Pain by Mitigating Neuronal Ferroptosis via the TLR2-COX-2 Pathway

Peipei Kang, Gujun Cong, Xiaowen Meng, Yang Zhang, Haiyan Sun, Lei Wang, Chao Zhang, Junyi Ma, Tong Liu, Fuhai Ji

Front. Biosci. (Landmark Ed) 2025, 30(9), 43761; https://doi.org/10.31083/FBL43761

Tetraspanin-Mediated ADAM10 Regulation in Sepsis and Potential Therapeutic Implications

Meiting Yang, Yao Lin, Yufu He, Shuanglin Liao, Yuting Qin, Lizhen Liu, Junbing He, Yiming Shao

Front. Biosci. (Landmark Ed) 2025, 30(9), 39386; https://doi.org/10.31083/FBL39386

LINC01605 Suppresses Esophageal Squamous Carcinogenesis by Regulating Squamous Cell Differentiation, Proliferation, and Migration

Xian Cheng, Xu Han, Haiyin An, Jialiang Fan, Junyi Li, Ting Xiao, Lin Feng, Shujun Cheng

Front. Biosci. (Landmark Ed) 2025, 30(9), 42805; https://doi.org/10.31083/FBL42805

One Size Does Not Fit All: Precision Combinations for FGFR4-driven Cancers

Emmy D.G. Fleuren

Front. Biosci. (Landmark Ed) 2025, 30(9), 43996; https://doi.org/10.31083/FBL43996

Insight into the Mechanism of Action of Prokaryotic SSB Interactomes

Piero R. Bianco, Cheng-Yang Huang

Front. Biosci. (Landmark Ed) 2025, 30(9), 36350; https://doi.org/10.31083/FBL36350

The Role of m6A Modification in Regulating MSC Differentiation and Immunomodulation: Implications for Regenerative Medicine and Therapeutic Applications

Junhui Zhao, Xiaoyun Zhang, Yanhui Wang, Yu Zeng, Hongliang Sun, Xiaodong Cui

Front. Biosci. (Landmark Ed) 2025, 30(9), 36475; https://doi.org/10.31083/FBL36475

Deiodinases’ Inhibitors: A Double-Edged Sword

Lucia Acampora, Caterina Miro, Annunziata Gaetana Cicatiello, Monica Dentice, Annarita Nappi

Front. Biosci. (Landmark Ed) 2025, 30(9), 40246; https://doi.org/10.31083/FBL40246

Microenvironment of Solid Tumors

Tatyana V. Korneenko, Nikolay B. Pestov, Mikhail I. Shakhparonov, Nickolai A. Barlev

Front. Biosci. (Landmark Ed) 2025, 30(9), 36940; https://doi.org/10.31083/FBL36940

The Role of in Tumor Immune Microenvironment Regulation: Insights and Future Directions

Bikesh K. Nirala, Jason T. Yustein

Front. Biosci. (Landmark Ed) 2025, 30(9), 37304; https://doi.org/10.31083/FBL37304

PTTG1IP Orchestrates Epithelial–Mesenchymal Transition and DNA Damage Response in Thyroid Cancer Progression

Henglu Zhang, Li Zhou, Suyu Wang, Di Yao, Jun Ma, Xiaoyan Hu, Wencheng Zhang, Mengyuan Tao, Min Wang, Weiping Lu

Front. Biosci. (Landmark Ed) 2025, 30(9), 44789; https://doi.org/10.31083/FBL44789