Therapeutic Applications of Vitamin D

Xiaolei Tang

Front. Biosci. (Landmark Ed) 2025, 30(4), 37218; https://doi.org/10.31083/FBL37218

TMC5 as a Marker of Tumor-Associated Telocytes in Hepatocellular Carcinoma

Ying Xu, Jing Yu

Front. Biosci. (Landmark Ed) 2025, 30(4), 36583; https://doi.org/10.31083/FBL36583

Role of NK Cells in Progression and Treatment of Multiple Myeloma

Iman Chanchiri, Emil Birch Christensen, Niels Abildgaard, Torben Barington, Thomas Lund, Jakub Krejcik

Front. Biosci. (Landmark Ed) 2025, 30(4), 26205; https://doi.org/10.31083/FBL26205

Sesamin Exerts Anti-Tumor Activity in Nasopharyngeal Carcinoma Through Inducing Autophagy and Reactive Oxygen Species Production

Deqiang An, Xianyao Jiang, Yucheng Yang

Front. Biosci. (Landmark Ed) 2025, 30(4), 26038; https://doi.org/10.31083/FBL26038

High-LET Proton Irradiation Significantly Alters the Clonogenic and Tumorigenic Potential of Human Breast Cancer Cell Lines and

Margarita Pustovalova, Rita Mohammad, Yuzhe Wang, Wenyu Xue, Philipp Malakhov, Viktor Nekrasov, Elizaveta Kontareva, Zain Nofal, Vyacheslav Saburov, Dmitry Kolesov, Andreyan Osipov, Sergey Leonov

Front. Biosci. (Landmark Ed) 2025, 30(4), 36415; https://doi.org/10.31083/FBL36415

NELFCD Promotes Colon Cancer Progression by Regulating the DUSP2–p38 Axis

Weiwei Dai, Min Zhu, Yujing Sun, Baohong Xu, Guorong Ma, Haiyun Shi, Peng Li

Front. Biosci. (Landmark Ed) 2025, 30(4), 25221; https://doi.org/10.31083/FBL25221

Epigenetic Reprogramming by Decitabine in Retinoblastoma

Lisa Gherardini, Ankush Sharma, Monia Taranta, Caterina Cinti

Front. Biosci. (Landmark Ed) 2025, 30(4), 33386; https://doi.org/10.31083/FBL33386

MgATPase Activity is Dispensable for the Pharmacological Regulation of the Functional Effects of the KATP Channels Opening in Brain Mitochondria

Olga V. Akopova, Anton Smirnov

Front. Biosci. (Landmark Ed) 2025, 30(4), 33450; https://doi.org/10.31083/FBL33450

M6A Methyltransferase METTL3 Modulates Traumatic Brain Injury by Targeting Ferroptosis

Fei Qin, Fan Li, Wenxiao Zhao, Suqin Zhang, Jiang Shen, Xinyu Yang

Front. Biosci. (Landmark Ed) 2025, 30(4), 31304; https://doi.org/10.31083/FBL31304

Functional and Mechanistic Insights into the Fatty-Acid CoA Ligase FadK in

Dafeng Liu, Ablikim Abdiriyim, Lvxia Zhang, Feng Yu

Front. Biosci. (Landmark Ed) 2025, 30(4), 36701; https://doi.org/10.31083/FBL36701

Acute Macular Neuroretinopathy Mediated by COVID-19 Infection: Insights into its Clinical Features and Pathogenesis

Yixuan Xi, Ziyi Zhou, Tianfang Chang, Guorui Dou, Zhaojie Chu

Front. Biosci. (Landmark Ed) 2025, 30(4), 26412; https://doi.org/10.31083/FBL26412

DTC-m6Am: A Framework for Recognizing N6,2′-O-dimethyladenosine Sites in Unbalanced Classification Patterns Based on DenseNet and Attention Mechanisms

Hui Huang, Fenglin Zhou, Jianhua Jia, Huachun Zhang

Front. Biosci. (Landmark Ed) 2025, 30(4), 36603; https://doi.org/10.31083/FBL36603

Macrophage Notch1 Participates in LPS-Induced Acute Lung Injury via Regulating CCR5 Expression in Mice

Ruiyu Zhang, Hui Du, Zhi Liu, Yuxi Lei, Huizhi Hu, Junwen Zheng, Pu Yang, Dongchi Zhao

Front. Biosci. (Landmark Ed) 2025, 30(4), 37430; https://doi.org/10.31083/FBL37430

(This article belongs to the Special Issue Cellular and Molecular Study in Immunopharmacology)

Targeting Platelet Activating Factor Signaling for Therapeutic Benefits in Neurodegenerative Disorders

Theodora Adamantidi, Andreas M. Grabrucker, Alexandros Tsoupras

Front. Biosci. (Landmark Ed) 2025, 30(4), 38300; https://doi.org/10.31083/FBL38300

Role of Tumor-Associated Macrophages in Breast Cancer Immunotherapy

Yan He, Quan Liu, Zhihao Luo, Qian Hu, Li Wang, Zifen Guo

Front. Biosci. (Landmark Ed) 2025, 30(4), 26995; https://doi.org/10.31083/FBL26995

(This article belongs to the Special Issue New Targets in Anticancer Therapy)

Unveiling RNA Editing by ADAR and APOBEC Protein Gene Families

Alexander Modestov, Anton Buzdin, Maria Suntsova

Front. Biosci. (Landmark Ed) 2025, 30(4), 26298; https://doi.org/10.31083/FBL26298

Socs3a is Dispensable for Zebrafish Hematopoiesis and is Required for Neuromast Formation

Mohamed Luban Sobah, Clifford Liongue, Alister C. Ward

Front. Biosci. (Landmark Ed) 2025, 30(4), 36537; https://doi.org/10.31083/FBL36537

Aerobic Exercise Ameliorates Alzheimer’s Disease-Like Pathology by Regulating Hepatic Phagocytosis of Aβ

Qing Wang, Feng-Rui Hu, Xing-Chun Gou, Shan Wang, Nai-Chun Ji

Front. Biosci. (Landmark Ed) 2025, 30(4), 36597; https://doi.org/10.31083/FBL36597

VSIG4 Alleviates Intracranial Hemorrhage Injury by Regulating Oxidative Stress and Neuroinflammation in Macrophages via the NRF2/HO-1 Signaling Pathway

Haofan Lu, Yuntao Li, Yonggang Zhang, Wen Qin, Zhongzhou Su, Sheng Qiu, Lifang Zheng

Front. Biosci. (Landmark Ed) 2025, 30(4), 37810; https://doi.org/10.31083/FBL37810

Brown Algae: Uncovering the Secrets of Evolutionary Genomics and Multicellularity

Gabriel Žoldák

Front. Biosci. (Landmark Ed) 2025, 30(4), 37380; https://doi.org/10.31083/FBL37380

XLOC_015548 Mitigates Skeletal Muscle Atrophy via the Gadd45g/MEK/ERK Pathway and Redox Regulation

Tiantian Qi, Haotian Qin, Fei Yu, Zimeng Zhou, Yingqi Chen, Peng Liu, Hui Zeng, Jian Weng

Front. Biosci. (Landmark Ed) 2025, 30(4), 36233; https://doi.org/10.31083/FBL36233

A Novel Signature Composed of Hypoxia, Glycolysis, Lactylation Related Genes to Predict Prognosis and Immunotherapy in Hepatocellular Carcinoma

Feng Yi, Shichao Long, Yuanbing Yao, Kai Fu

Front. Biosci. (Landmark Ed) 2025, 30(4), 33422; https://doi.org/10.31083/FBL33422

The Flow of Life: Convergent Approaches to Understanding Musculoskeletal Health from Molecular- to Meso-Length Scales

Melissa Louise Knothe Tate

Front. Biosci. (Landmark Ed) 2025, 30(4), 25231; https://doi.org/10.31083/FBL25231

(This article belongs to the Special Issue Vascular Mechanisms in Skeletal Disease)

Co-Highly Expressed and as Potential Prognostic Biomarkers and Therapeutic Targets in Clear Cell Renal Cell Carcinoma

Zongpan Ke, Zhiwang Tang, Deyun Shen, Yixun Liu, Yawei Shu, Xiangyu Mu, Zexuan Li, Ping Xiang, Bing Zhong, Xuechun Hu, Ruoyun Tan, Jun Xiao

Front. Biosci. (Landmark Ed) 2025, 30(4), 38061; https://doi.org/10.31083/FBL38061

Strategies for Drug Discovery to Modulate Macromolecular Interactions Altered by Mutations

Pitambar Poudel, Maria A. Miteva, Emil Alexov

Front. Biosci. (Landmark Ed) 2025, 30(4), 26339; https://doi.org/10.31083/FBL26339

Cross-Species Multi-Omics Analysis Reveals Myeloid-Driven Endothelial Oxidative Stress in Ischemic Stroke

Ziqi Cheng, Hua Zhu, Shi Feng, Yonggang Zhang, Xiaoxing Xiong

Front. Biosci. (Landmark Ed) 2025, 30(4), 37429; https://doi.org/10.31083/FBL37429

The Potential and Challenges of Human Pluripotent Stem Cells in the Treatment of Diabetic Nephropathy

Wanyue Xu, Fangyu Yi, Haiyang Liao, Caifeng Zhu, Xiaodi Zou, Yanzhao Dong, Weijie Zhou, Zexing Sun, Jiazhen Yin

Front. Biosci. (Landmark Ed) 2025, 30(4), 28283; https://doi.org/10.31083/FBL28283

(This article belongs to the Special Issue Genetic Modulation of Human Pluripotent Stem Cells)

Knockdown of can Induce Pyroptosis to Inhibit the Progression of Hepatocellular Carcinoma

Xiaoliang Lu, Jie Chen, Zefa Lu, Hong Zang

Front. Biosci. (Landmark Ed) 2025, 30(4), 26654; https://doi.org/10.31083/FBL26654

Deciphering the Role of Oxidative Stress in Male Infertility: Insights from Reactive Oxygen Species to Antioxidant Therapeutics

Ye Zhou, Hengyan Zhang, Heguo Yan, Pingxing Han, Jing Zhang, Yangwen Liu

Front. Biosci. (Landmark Ed) 2025, 30(4), 27046; https://doi.org/10.31083/FBL27046

Angiopoietin-Like Protein Family-Mediated Functions in Modulating Triglyceride Metabolism and Related Metabolic Diseases

Sen Yang, Xin Su, Min Lai, Xiaoxi Liu, Ye Cheng

Front. Biosci. (Landmark Ed) 2025, 30(4), 25862; https://doi.org/10.31083/FBL25862

Early and Late Responses of Cultured Human Mesenchymal Stem Cells (MSCs) to Cell-free DNA (cfDNA) in Patients With Acute Myocardial Infarction

Elena M. Malinovskaya, Natalia N. Veiko, Elisaveta S. Ershova, Larisa V. Kameneva, Marina S. Konkova, Svetlana V. Kostyuk

Front. Biosci. (Landmark Ed) 2025, 30(4), 28255; https://doi.org/10.31083/FBL28255

Persister Intestinal Bacteria, Epigenetics and Major Depression

Luis Vitetta, Matthew Bambling, Esben Strodl

Front. Biosci. (Landmark Ed) 2025, 30(4), 26837; https://doi.org/10.31083/FBL26837

(This article belongs to the Special Issue Molecular and Cellular Aspects of Depression)

Linker Histones Maintain Genome Stability and Drive the Process of Cellular Ageing

George Miloshev, Penyo Ivanov, Bela Vasileva, Milena Georgieva

Front. Biosci. (Landmark Ed) 2025, 30(4), 26823; https://doi.org/10.31083/FBL26823

Elucidating the Role of Nrf2 Signaling Pathway in Infections

Sarmistha Saha, Nadezhda Sachivkina, Olga Kuznetsova, Ekaterina Neborak, Natallia Zhabo

Front. Biosci. (Landmark Ed) 2025, 30(4), 28286; https://doi.org/10.31083/FBL28286

Yolkin Ameliorates Effects of the Psychic Stress on the Contact Sensitivity, Cell Proliferation, and Cytokine Production in Mice

Michał Zimecki, Jolanta Artym, Maja Kocięba, Ewa Zaczyńska, Katarzyna Kaleta-Kuratewicz, Jan P. Madej, Piotr Kuropka, Aleksandra Zambrowicz, Łukasz Bobak

Front. Biosci. (Landmark Ed) 2025, 30(4), 27949; https://doi.org/10.31083/FBL27949

(This article belongs to the Special Issue Cellular and Molecular Study in Immunopharmacology)