New Targets in Anticancer Therapy
Submission Deadline: 31 Mar 2025
Guest Editor
Special Issue Information
Dear Colleagues,
Cancer is a leading cause of morbidity and mortality worldwide, and the development of effective and targeted therapies is a major focus of current cancer research. There are a variety of modern approaches to the treatment of cancer, including chemotherapy, targeted therapies, immunotherapies, gene therapies, targeted radiotherapy, and targeted surgery.
Targeted cancer therapies are designed to specifically act on the molecular and cellular abnormalities that drive cancer growth and proliferation, and have the potential to offer improved efficacy and reduced side effects compared to traditional chemotherapy.
It is important to note that targeted therapies are typically used in combination with other cancer treatments, such as chemotherapy or radiation therapy, and the choice of therapy will depend on the specific type of cancer being treated.
Overall, modern anticancer approaches aim to specifically target the abnormalities that drive cancer growth and proliferation, and offer the potential for improved efficacy and reduced side effects compared to traditional chemotherapy.
This Special Issue will include the following topics:
• Precision medicine
• Targeted therapy, gene-editing therapies
• Immuno-oncology targets, monoclonal antibodies, small molecule inhibitors
• DNA damage response (DDR) targets
• Oncogenic kinases
• Autophagy targets
• Epigenetic targets
Dr. Milena Georgieva
Guest Editor
Published Papers (8)
Interrogating the Involvement of Autophagy, Senescence, and the Immune System in the Actions of Sacituzumab Govitecan as an Anticancer Agent
Front. Biosci. (Landmark Ed) 2025, 30(11), 39310; https://doi.org/10.31083/FBL39310 (registering DOI)
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
Inhibition of Phosphoglycerate Kinase 1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma to X-rays and Carbon Ion Irradiation
Front. Biosci. (Landmark Ed) 2025, 30(5), 36430; https://doi.org/10.31083/FBL36430
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
Role of Tumor-Associated Macrophages in Breast Cancer Immunotherapy
Front. Biosci. (Landmark Ed) 2025, 30(4), 26995; https://doi.org/10.31083/FBL26995
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target
Front. Biosci. (Landmark Ed) 2024, 29(1), 41; https://doi.org/10.31083/j.fbl2901041
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
An Update on Gemcitabine-Based Chemosensitization Strategies in Pancreatic Ductal Adenocarcinoma
Front. Biosci. (Landmark Ed) 2023, 28(12), 361; https://doi.org/10.31083/j.fbl2812361
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
Identification of Potential Inhibitors Targeting GTPase-Kirsten RAt Sarcoma Virus (K-Ras) Driven Cancers via E-Pharmacophore-Based Virtual Screening and Drug Repurposing Approach
Front. Biosci. (Landmark Ed) 2023, 28(11), 288; https://doi.org/10.31083/j.fbl2811288
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
LINC01572 is a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma
Front. Biosci. (Landmark Ed) 2023, 28(10), 257; https://doi.org/10.31083/j.fbl2810257
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
Comparative Proteomic Analysis of Irradiation-Induced Radioresistant Breast Cancer Cells Using Label-Free Quantitation
Front. Biosci. (Landmark Ed) 2023, 28(10), 244; https://doi.org/10.31083/j.fbl2810244
(This article belongs to the Special Issue New Targets in Anticancer Therapy)
