Significance of Mitochondrial Dysfunction in the Pathogenesis of Parkinson's Disease

Alexander Blagov, Anton Postnov, Vasily Sukhorukov, Mikhail Popov, Jamol Uzokov, Alexander Orekhov

Front. Biosci. (Landmark Ed) 2024, 29(1), 36; https://doi.org/10.31083/j.fbl2901036

Early Estrogen Replacement Therapy Attenuates Cardiac Dysfunction Caused by Aging and Ovariectomy in Female Wistar Rats

Diana Ramírez-Hernández, Pedro López-Sanchez, Diego Lezama-Martínez, Erik Pérez-García, M. Fernanda Skat Montoya-Hernández, Alberto Aranda-Fraustro, Jazmin Flores-Monroy

Front. Biosci. (Landmark Ed) 2024, 29(1), 46; https://doi.org/10.31083/j.fbl2901046

(This article belongs to the Special Issue Lipids and lipid metabolism in cardiovascular disease)

Ferroptosis: New Strategies and Ideas for the Treatment of Pancreatic Ductal Adenocarcinoma

Chengru Yang, Qingfu Dong, Haolin Bao, Yifei Ge, Zhaoqiang Xu, Jinglin Li, Xingming Jiang, Yi Xu, Xiangyu Zhong

Front. Biosci. (Landmark Ed) 2024, 29(1), 45; https://doi.org/10.31083/j.fbl2901045

MiR-145 Alleviates Sepsis-Induced Inflammatory Responses and Organ Injury by Targeting ADAM17

Yingying Lin, Lizhen Liu, Yao Lin, Ruoxuan Yang, Shuanglin Liao, Mingwei Xu, Junbing He, Qinghua Liu

Front. Biosci. (Landmark Ed) 2024, 29(1), 44; https://doi.org/10.31083/j.fbl2901044

(This article belongs to the Special Issue The Pathogenesis of Sepsis)

Pharmacological Basis for the Antidiarrheal and Antispasmodic Effects of Cuminaldehyde in Experimental Animals: In Silico, Ex Vivo and In Vivo Studies

Mohd Nazam Ansari, Najeeb Ur Rehman, Abdul Samad, Wasim Ahmad

Front. Biosci. (Landmark Ed) 2024, 29(1), 43; https://doi.org/10.31083/j.fbl2901043

Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review

Marveh Rahmati, Maria Paula Kwesiga, Jiachen Lou, Ai Lyn Tan, Michael F McDermott

Front. Biosci. (Landmark Ed) 2024, 29(1), 42; https://doi.org/10.31083/j.fbl2901042

Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target

Shilpee Chanda, Konstantin Lepikhov, Charlotte Dahlem, Hanna S. Schymik, Jessica Hoppstädter, An-Kristin Geber, Konrad Wagner, Sonja M. Kessler, Martin Empting, Alexandra K. Kiemer

Front. Biosci. (Landmark Ed) 2024, 29(1), 41; https://doi.org/10.31083/j.fbl2901041

(This article belongs to the Special Issue New Targets in Anticancer Therapy)

Sanguinarine Triggers Apoptosis in Cutaneous Squamous Cell Carcinoma Cells through Reactive Oxygen Species-Dependent c-Jun N-Terminal Kinase Signaling Pathway

Kalyani Patil, Abdul Q Khan, Fareed Ahmad, Shilpa Kuttikrishnan, Rasheeda Anver, Jericha M. Mateo, Aamir Ahmad, Ajaz A. Bhat, Joerg Buddenkotte, Martin Steinhoff, Shahab Uddin

Front. Biosci. (Landmark Ed) 2024, 29(1), 40; https://doi.org/10.31083/j.fbl2901040

Bioinformatics Analysis Identifies PLA2G7 as a Key Antigen-Presenting Prognostic Related Gene Promoting Hepatocellular Carcinoma through the STAT1/PD-L1 Axis

Sihang Guo, Qinhe Yang

Front. Biosci. (Landmark Ed) 2024, 29(1), 39; https://doi.org/10.31083/j.fbl2901039

(This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

High-Throughput Sequencing to Investigate the Expression and Potential Role of Differentially Expressed microRNAs in Myocardial Cells after Ischemia-Reperfusion Injury

Senjie Li, Dongqing Lv, Yan Lu, Yanwei Zhang, Yongping Jia

Front. Biosci. (Landmark Ed) 2024, 29(1), 38; https://doi.org/10.31083/j.fbl2901038

Recent Advance of S100B Proteins in Spontaneous Intracerebral Hemorrhage and Aneurysmal Subarachnoid Hemorrhage

Zhang-Ming Zhou, Ling-Ling Gu, Zhe-Yu Zhou, Qing-Le Liang

Front. Biosci. (Landmark Ed) 2024, 29(1), 37; https://doi.org/10.31083/j.fbl2901037

Downregulation of MTHFD2 Inhibits Proliferation and Enhances Chemosensitivity in Hepatocellular Carcinoma via PI3K/AKT Pathway

Jie Wang, Ze Yu, Yixiao Jiang, Ting Le, Yixin Wu, Ziqi Li, Guoqiang Zhang, Feiyue Wu, Haijie Ma

Front. Biosci. (Landmark Ed) 2024, 29(1), 35; https://doi.org/10.31083/j.fbl2901035

Developing Humanized Animal Models with Transplantable Human iPSC-Derived Cells

Min Ma, Jian-Yun Ge, Yun-Zhong Nie, Yu-Mei Li, Yun-Wen Zheng

Front. Biosci. (Landmark Ed) 2024, 29(1), 34; https://doi.org/10.31083/j.fbl2901034

N⁶-Methyladenosine Regulator-Mediated Methylation Modification Patterns with Distinct Prognosis, Oxidative Stress, and Tumor Microenvironment in Renal Cell Carcinoma

Chunyang Li, Maoshu Zhu, Chuane Gao, Fuhua Lu, Huoshu Chen, Jiancheng Liu, Weimin Zhong

Front. Biosci. (Landmark Ed) 2024, 29(1), 33; https://doi.org/10.31083/j.fbl2901033

(This article belongs to the Special Issue Targeting of Multiple Predictive Biomarkers for Checkpoint Immunotherapy)

O-glycoprofiling of Serum Apolipoprotein C-III in Colorectal Cancer

Kristína Kianičková, Zuzana Pakanová, Filip Květoň, Alena Holazová, Paras H. Kundalia, Peter Baráth, Goran Miljuš, Olgica Nedić, Jaroslav Katrlík

Front. Biosci. (Landmark Ed) 2024, 29(1), 32; https://doi.org/10.31083/j.fbl2901032

(This article belongs to the Special Issue Gastrointestinal Cancer: Pathogenesis, Carcinogenesis and Targeted Therapies)

Protective Properties of Botanical Extracts against 5G Radiation-induced Damage to Human Skin, as Demonstrated in Preliminary Data from a Keratinocyte Cell Culture Model

Fabien Havas, Moshe Cohen, Shlomo Krispin, Joan Attia-Vigneau

Front. Biosci. (Landmark Ed) 2024, 29(1), 31; https://doi.org/10.31083/j.fbl2901031

(This article belongs to the Special Issue Antiaging in Dermatology)

Autophagy, Ferroptosis, Apoptosis and Pyroptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease

Shuangshuang Zhao, Yan Guo, Xunzhe Yin

Front. Biosci. (Landmark Ed) 2024, 29(1), 30; https://doi.org/10.31083/j.fbl2901030

(This article belongs to the Special Issue Cellular and Molecular Mechanisms of Metabolic Liver Disease-associated Hepatocellular Carcinoma)

Cytokine Profiling in Aqueous Humor of Glaucoma Patients and in Retinas from an Ex Vivo Glaucoma Animal Model

Jiancen Tang, Mengsha Sun, Yuan Feng, Verena Prokosch, Hongping Cui, Hanhan Liu

Front. Biosci. (Landmark Ed) 2024, 29(1), 29; https://doi.org/10.31083/j.fbl2901029

(This article belongs to the Special Issue Retinal Biology in Health and Disease)

The Centrosomes of Haploid and Diploid Cells Have an Equal Number of Centrioles in the Parasitoid Wasp Anisopteromalus Calandrae

Rustem Uzbekov, San-Whouly Mauricette Ouali N'goran, Anastasiia Garanina, Massimo Pancione, Stanislav Yu. Chaika, Christophe Bressac

Front. Biosci. (Landmark Ed) 2024, 29(1), 28; https://doi.org/10.31083/j.fbl2901028

KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2

Qiaohong Bai, Wenfang Jin, Futao Chen, Jiang Zhu, Lifeng Cao, Yang Yang, Fukuan Zhong, Li Li

Front. Biosci. (Landmark Ed) 2024, 29(1), 27; https://doi.org/10.31083/j.fbl2901027

The Regulatory Role and Mechanism of Energy Metabolism in Vascular Diseases

Taoli Sun, Wei Yuan, Yu Wei, Duanfang Liao, Qinhui Tuo

Front. Biosci. (Landmark Ed) 2024, 29(1), 26; https://doi.org/10.31083/j.fbl2901026

Quantitative Proteomics Analysis Reveals the Potential Role of lncRNA FTX in Endothelial Cells

Qi Zhao, Yadi Lan, Xiuju Shi, Xiangfei Sun

Front. Biosci. (Landmark Ed) 2024, 29(1), 25; https://doi.org/10.31083/j.fbl2901025

Polycystic Ovary Syndrome Pathophysiology: Integrating Systemic, CNS and Circadian Processes

George Anderson

Front. Biosci. (Landmark Ed) 2024, 29(1), 24; https://doi.org/10.31083/j.fbl2901024

Advancements in the ERK1/2 Signaling Pathway Affecting Male Reproduction

Yikuan Du, Xianhong Chi, Yuni Wang, Xiaolin Cai, Wenqi Zeng, Yuying Huo, Mengting Zhang, Zhenjie Wang, Zhuoming Guo, Jingnan Qiu, Zhendong Ma, Weichui Zhang, Jinfeng Zhu, Chun Yang

Front. Biosci. (Landmark Ed) 2024, 29(1), 23; https://doi.org/10.31083/j.fbl2901023

Unveiling the Intricacies of Autophagy in Asthma: Unraveling Novel Therapeutic Avenues

Junjun Peng, Na Lu, Shucheng Hua, Lei Song, Han Liu

Front. Biosci. (Landmark Ed) 2024, 29(1), 22; https://doi.org/10.31083/j.fbl2901022

(This article belongs to the Special Issue Molecular Mechanisms of Inflammatory and Metabolic Diseases)

Identifying Autophagy-Associated Proteins and Chemicals with a Random Walk-Based Method within Heterogeneous Interaction Network

FeiMing Huang, Wei Guo, Lei Chen, KaiYan Feng, Tao Huang, Yu-Dong Cai

Front. Biosci. (Landmark Ed) 2024, 29(1), 21; https://doi.org/10.31083/j.fbl2901021

Machine and Deep Learning: Artificial Intelligence Application in Biotic and Abiotic Stress Management in Plants

Caiming Gou, Sara Zafar, Fatima, Zuhair Hasnain, Nazia Aslam, Naeem Iqbal, Sammar Abbas, Hui Li, Jia Li, Bo Chen, Arthur J. Ragauskas, Manzar Abbas

Front. Biosci. (Landmark Ed) 2024, 29(1), 20; https://doi.org/10.31083/j.fbl2901020

Novel Signaling Pathway and NSC689534 as a Potential Drug Candidate for Cutaneous Squamous Cell Carcinoma

Ying Miao, Cheng Shen, Xin Zhang, Qi-Qi Li, A-Ying Pang, Wen-Min Zhao, Xiao-Yan Wu, Hong-Yan Qian, Xiao-Dong Chen

Front. Biosci. (Landmark Ed) 2024, 29(1), 19; https://doi.org/10.31083/j.fbl2901019

A Case-Control Study of the Associations between EGLN1 Gene Polymorphisms and COPD

Xin Li, Peng Zhang, Jing Yu, Chunyan Zhang, Yanli Shi, Xueyan Wei, Honge Li, Xuhui Zhang, Ao Lin, Zhen Yang, Yunchao Wang, Xinhua Wang

Front. Biosci. (Landmark Ed) 2024, 29(1), 18; https://doi.org/10.31083/j.fbl2901018

ACE2 Regulates Glycolipid Metabolism in Multiple Tissues

Rui Li, Fangyu Li, Li Yuan

Front. Biosci. (Landmark Ed) 2024, 29(1), 17; https://doi.org/10.31083/j.fbl2901017

Role of SLC5A8 as a Tumor Suppressor in Cervical Cancer

Orlando Vargas-Sierra, Jennifer Hernández-Juárez, Perla Yaceli Uc-Uc, Luis A Herrera, Guadalupe Domínguez-Gómez, Patricio Gariglio, José Díaz-Chávez

Front. Biosci. (Landmark Ed) 2024, 29(1), 16; https://doi.org/10.31083/j.fbl2901016

Huaier Regulates Oxaliplatin Resistance in Colorectal Cancer by Regulating Autophagy and Inhibiting the Wnt/$\beta$-catenin Signalling Pathway

Qi Feng, Mingyi Huo, Xiaoli Yan, Luwen Wen, Jining Zheng

Front. Biosci. (Landmark Ed) 2024, 29(1), 15; https://doi.org/10.31083/j.fbl2901015

DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-$\kappa$B/IFI27 Signaling Pathway

Yumei Han, Jinbo Gao, Lei Liu

Front. Biosci. (Landmark Ed) 2024, 29(1), 14; https://doi.org/10.31083/j.fbl2901014

Multi-Omics Characteristics of Ferroptosis Associated with Colon Adenocarcinoma Typing and Survival

Xiao-Qiong Chen, Ke Lian, Zi-Wei Chen, Xuan Zhang, Ting Li, Tao Wu, Tao Shen, Xin-Yi Cai, Xian-Shuo Cheng, Fu-Hui Xiao, Yun-Feng Li

Front. Biosci. (Landmark Ed) 2024, 29(1), 13; https://doi.org/10.31083/j.fbl2901013

(This article belongs to the Special Issue Multi-Omics Biomarker Signatures in Precision Cancer Medicine)

Dissecting the Clinical Heterogeneity and Genotype-Phenotype Correlations of MAPT Mutations: A Systematic Review

Cristina Villa, Elisa Pellencin, Aurora Romeo, Giorgio Giaccone, Giacomina Rossi, Sara Prioni, Paola Caroppo

Front. Biosci. (Landmark Ed) 2024, 29(1), 12; https://doi.org/10.31083/j.fbl2901012

Differential Protection of Chickens against Highly Pathogenic H5 Avian Influenza Virus Using Polybasic Amino Acids with H5 Cleavage Peptide

Sang Heui Seo

Front. Biosci. (Landmark Ed) 2024, 29(1), 11; https://doi.org/10.31083/j.fbl2901011

Seasonal Influence on Salivary Myeloperoxidase Diurnal Variations in Young Healthy Subjects: A Preliminary Study

Kacper Nijakowski, Rafał Rutkowski, Dawid Gruszczyński, Janusz Witowski, Anna Surdacka, Dominika Kanikowska

Front. Biosci. (Landmark Ed) 2024, 29(1), 10; https://doi.org/10.31083/j.fbl2901010

Association of 10 Genetic Variations and 10 Environmental Factors with Myopia of Different Severities in Different Age Groups of People in Northeast China

Yan Sun, Zhuang Li, Zhuoshi Wang, Xingru He, Sile Yu, Lan Hu, Ling Xu, Wei He

Front. Biosci. (Landmark Ed) 2024, 29(1), 9; https://doi.org/10.31083/j.fbl2901009

Potential Alternative Receptors for SARS-CoV-2-Induced Kidney Damage: TLR-4, KIM-1/TIM-1, and CD147

Nada J. Habeichi, Ghadir Amin, Bachir Lakkis, Rayane Kataya, Mathias Mericskay, George W. Booz, Fouad A. Zouein

Front. Biosci. (Landmark Ed) 2024, 29(1), 8; https://doi.org/10.31083/j.fbl2901008

Application of Genomic Data in Translational Medicine During the Big Data Era

Yun Zhang, Jian Yu, Xiaoyan Xie, Feng Jiang, Chuyan Wu

Front. Biosci. (Landmark Ed) 2024, 29(1), 7; https://doi.org/10.31083/j.fbl2901007

ARHGAP6 Suppresses Breast Cancer Tumor Growth by Promoting Ferroptosis via RhoA-ROCK1-p38 MAPK Signaling

Xiaoqing Chen, Jing Zhu, Xiangzhi Li, Jintao Chen, Zhisheng Zhou, Xulong Fan, Ruijian Liang, Haiyan Liu, Dajiang Zhu

Front. Biosci. (Landmark Ed) 2024, 29(1), 6; https://doi.org/10.31083/j.fbl2901006

SIRT6 Reduces Rheumatoid Arthritis Injury by Inhibiting MyD88-ERK Signaling Pathway

Xiaolong Yu, Zihan Jin, Faisal Raza, Ping Zhang, Jiabiao Wu, Min Ren, Jiapeng Wang, Jing Xi

Front. Biosci. (Landmark Ed) 2024, 29(1), 5; https://doi.org/10.31083/j.fbl2901005

Parkinson's Disease Diagnosis Using miRNA Biomarkers and Deep Learning

Alex Kumar, Valentina L. Kouznetsova, Santosh Kesari, Igor F. Tsigelny

Front. Biosci. (Landmark Ed) 2024, 29(1), 4; https://doi.org/10.31083/j.fbl2901004

Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics

Xiaoman Zhou, Xiuyuan Wang, Ruizhen Bai, Hanjie Li, Dong Hua, Xiao-Dong Gao, Ganglong Yang, Quan Liu

Front. Biosci. (Landmark Ed) 2024, 29(1), 3; https://doi.org/10.31083/j.fbl2901003

Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer

Yanan Cheng, Li Dong, Dechao Bu, Lei Han, Yi Zhao, Juntian Liu, Xiaojing Guo, Hanli Xu, Jinpu Yu

Front. Biosci. (Landmark Ed) 2024, 29(1), 2; https://doi.org/10.31083/j.fbl2901002

Genome-Wide Identification of R2R3-MYB Family Genes and Their Response to Stress in Dendrobium nobile

Liping Wu, Jizhou Fan, Xinglong Su, Daiyin Peng, Shihai Xing

Front. Biosci. (Landmark Ed) 2024, 29(1), 1; https://doi.org/10.31083/j.fbl2901001