Dear Colleagues,

Improved therapeutic strategies for gastrointestinal cancer can be developed through a comprehensive transdisciplinary approach. Colorectal cancer, for example, can be examined microscopically using small tissue sections obtained from the tumor core (tissue microarray,TMA). This is not possible with gastric cancer, however, due to the highly variable tissue architecture and molecular profile.  The aim of this special issue is to collect papers that focus on understanding gastrointestinal cancers from the oral mucosa to the anal canal based on experimental, in vivo and ex-vivo studies. All types of research that result in a better understanding of cancer could lead to findings with a prognostic or predictive impact. Research that presents data on primary or metastatic tumors from the liver and pancreas are also welcome. The overall aim of this special issue is therefore to provide an update on the tumorigenesis and targeted therapy of heterogeneous cancers.  

Dr. Simona Gurzu 
Guest Editor