METTL3-Driven m6A Modification of Gene in High Fat Diet Related Liver Cancer Tumor Macrophages Facilitates Type II Macrophage Differentiation

Limei Zhu, Xuelian Li, Wenting Wang

Front. Biosci. (Landmark Ed) 2025, 30(5), 36971; https://doi.org/10.31083/FBL36971

Interferon-α2b Modulates AMPA and Kainate Receptors and Alters Cross Talk of AMPA and NMDA Receptors in the Frog Vestibular Epithelium

Irina V. Ryzhova, Elena A. Vershinina, Alexander G. Markov, Tatyana V. Tobias

Front. Biosci. (Landmark Ed) 2025, 30(5), 38852; https://doi.org/10.31083/FBL38852

A Highly Selective and Sensitive Fluorescent Probe With a Large Stokes Shift for Near-Infrared Visualization of Endogenous and Exogenous Biothiols in Living Cells

Xiaomin Li, Rongrong Yuan, Yangmin Ma, Guanglong Li, Siyue Ma

Front. Biosci. (Landmark Ed) 2025, 30(5), 37240; https://doi.org/10.31083/FBL37240

HMGB1 Mediates Microglia-Astrocyte/Neuron Crosstalk and Pyroptosis by the TLR4/NF-κB Pathway in Multiple Sclerosis

Yang Feng, Liang Wang, Zhuofeng Mao, Weiping Wang

Front. Biosci. (Landmark Ed) 2025, 30(5), 37838; https://doi.org/10.31083/FBL37838

Inhibition of Phosphoglycerate Kinase 1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma to X-rays and Carbon Ion Irradiation

Junru Chen, Hongtao Luo, Xun Wu, Meng Dong, Dandan Wang, Yuhong Ou, Yuhang Wang, Shilong Sun, Zhiqiang Liu, Zhen Yang, Quanlin Guan, Qiuning Zhang

Front. Biosci. (Landmark Ed) 2025, 30(5), 36430; https://doi.org/10.31083/FBL36430

(This article belongs to the Special Issue New Targets in Anticancer Therapy)

Knockdown Increases the Sensitivity of Hepatocellular Carcinoma Cells to Sorafenib by Disrupting miR-145-5p/HK2 Axis-Mediated Mitochondrial Function and Glycolysis

Meiyu Cheng, Bingrong Wang, Lina Duan, Yu Jin, Wenda Zhang, Na Li

Front. Biosci. (Landmark Ed) 2025, 30(5), 37368; https://doi.org/10.31083/FBL37368

(This article belongs to the Special Issue Regulated Cell Death and Disease)

Obesity-Derived Biomolecules Promote the Differentiation of THP1 Monocytes to Macrophages

Luis I. Terrazas, Valeria Gutiérrez-Almaraz, Valentina García-Garay, Victoria Hernández-Gómez, Nohemí Salinas-Jazmín, Mónica Graciela Mendoza-Rodríguez, Jonadab Efraín Olguín

Front. Biosci. (Landmark Ed) 2025, 30(5), 36637; https://doi.org/10.31083/FBL36637

Trimethylamine N-oxide Supplementation Enhances the Quality of Oocytes in Mice of Polycystic Ovary Syndrome

Jiayu Huang, Yin Tian, Xuemei Liu, Zixin Xu, Chong Li, Ling Zhu, Xiru Liu, Jiying Hou, Jingyu Li

Front. Biosci. (Landmark Ed) 2025, 30(5), 38078; https://doi.org/10.31083/FBL38078

TNIK Regulates Cytoskeletal Organization to Promote Focal Adhesion Turnover and Mitosis in Lung Adenocarcinoma

Yao Li, Meng-yao Song, Xing Hu, Xue-hua Sun, Tao Zhang, Lu Zhang, Ying-xiong Wang, Qian Zhang, Chun-dong Zhang, Lian Zhang

Front. Biosci. (Landmark Ed) 2025, 30(5), 38875; https://doi.org/10.31083/FBL38875

Swimming Training in a T2DM Zebrafish Model Restores Mitochondrial Function to Alleviate Anxiety-Like Behaviors and Metabolic Dysregulation

Yimeng Fang, Junying Qu, Jing Zhao, Linkai Qu, Lei Wang, Cheng Luo, Qinsi Yang, Wei Wu, Da Sun, Dongjuan He

Front. Biosci. (Landmark Ed) 2025, 30(5), 37100; https://doi.org/10.31083/FBL37100

The Role of Formononetin in Cerebral Ischemia-Reperfusion Injury: A New Mediator of c-Fos/IL-10/STAT3 Signaling Pathway

Ming Yan, Fuyong Ni, Xue Xie, Chenfeng Zhang, Jing Zhu

Front. Biosci. (Landmark Ed) 2025, 30(5), 26274; https://doi.org/10.31083/FBL26274

Role of ERK1/2 and p38 Protein Kinases in Tumors: Biological Insights and Clinical Implications

Aleksandra Emelyanova, Alexander Modestov, Anton Buzdin, Elena Poddubskaya

Front. Biosci. (Landmark Ed) 2025, 30(5), 31317; https://doi.org/10.31083/FBL31317

Mechanism of Regulation of Glutamine Metabolism to Promote Ferroptosis Sensitivity in Endometriosis

Hui-Yu Ma, Huan-Yu Wu, Yu-Ting Xiang, Yu-Yin Liu, Jin Xie, Peng-Yu Cai, Bin Zhang, Yu-Hang Zhang, Ming-Xiu Wu

Front. Biosci. (Landmark Ed) 2025, 30(5), 36781; https://doi.org/10.31083/FBL36781

Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: and Studies

Hassan A. Madkhali, Mohd Nazam Ansari, Mubarak A. Alamri

Front. Biosci. (Landmark Ed) 2025, 30(5), 38395; https://doi.org/10.31083/FBL38395

Comparative Analysis of the Bioactivity and Anti-Inflammatory Effects Against Endotoxin in Mitochondria for Transplantation: Impact of Muscle Origin in Rats

Da-Wei Huang, Heng-Juei Hsu, Pei-Wen Chen, Ming-Tse Wu, Chia-En Wong, Chi-Chen Huang, Po-Hsuan Lee, Hui-Fang Chen, Jung-Shun Lee

Front. Biosci. (Landmark Ed) 2025, 30(5), 37367; https://doi.org/10.31083/FBL37367

(This article belongs to the Special Issue Mitochondria Targeting Strategies for Treatment of Human Diseases)

The Role of Matrix Metalloproteinases in Liver Function and Disease

Gregoria Mitropoulou, Vasiliki Kompoura, Francesca Saffioti, Vasileios K. Mavroeidis

Front. Biosci. (Landmark Ed) 2025, 30(5), 27127; https://doi.org/10.31083/FBL27127

Inborn Errors of Immunity in Apoptosis

Nadia Makkoukdji, Travis Satnarine, Alana Xavier de Almeida, Matthew Wyke, Iris H. Kim, Gary I. Kleiner, Melissa Gans

Front. Biosci. (Landmark Ed) 2025, 30(5), 27231; https://doi.org/10.31083/FBL27231

Neutrophil Extracellular Trap Formation Suppressed by Ro 106-9920 Enhances Diabetic Wound Healing by Blocking NLRP3 Inflammasome Activation

Hua Li, Lihua Xu, Jingying Chen, Huijuan Huang, Feiteng Liang, Shuxiao Li, Fuda Huang, Junyu Guo

Front. Biosci. (Landmark Ed) 2025, 30(5), 37393; https://doi.org/10.31083/FBL37393

The Role of CEBPD in Oxidative Stress and Angiogenesis Regulation in Endometriosis

Jing Su, Peipei Tang, Jixiang Zhong, Rongxue Zhang, Huiying Xue, Hong Zhang

Front. Biosci. (Landmark Ed) 2025, 30(5), 33488; https://doi.org/10.31083/FBL33488

Chick Embryo Chorioallantoic Membrane (CAM) Model for Cancer Studies and Drug Evaluation

Yuzhe Wang, Wenyu Xue, Margarita Pustovalova, Denis V Kuzmin, Sergey Leonov

Front. Biosci. (Landmark Ed) 2025, 30(5), 37456; https://doi.org/10.31083/FBL37456

Oleandrin Promotes Apoptosis in an Autophagy-Dependent Manner in Gastric Cancer

Xiaoyan Huang, Liting Yan, Xiangrong Zhao, Ying Wang, Huiting Li, Xinlu Jiang, Yangmeng Feng, Dandan Ouyang, Cuixiang Xu, Jianhua Wang

Front. Biosci. (Landmark Ed) 2025, 30(5), 26608; https://doi.org/10.31083/FBL26608

Advances in Melanoma Treatment with Salvianolic Acid A

Chan-Yen Kuo

Front. Biosci. (Landmark Ed) 2025, 30(5), 36577; https://doi.org/10.31083/FBL36577

Acquired Piezo2 Channelopathy is One Principal Gateway to Pathophysiology

Balázs Sonkodi

Front. Biosci. (Landmark Ed) 2025, 30(5), 33389; https://doi.org/10.31083/FBL33389

(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

Plant HS and Transcription Factors (TFs) Interactions: Unexplored Area

Francisco J Corpas

Front. Biosci. (Landmark Ed) 2025, 30(5), 27736; https://doi.org/10.31083/FBL27736

Molecular Mechanisms and Therapeutic Targeting of Heat Shock Proteins (HSPs) in Cardiovascular Disorders

Jyoti Upadhyay, Mukesh Nandave, Kamal Y. Thajudeen, Summya Rashid, Mohd Nazam Ansari

Front. Biosci. (Landmark Ed) 2025, 30(5), 27324; https://doi.org/10.31083/FBL27324

Investigation Into the Pathogenesis of Type 2 Cardiorenal Syndrome via the ROS–TRPM2 Signaling Axis

Yanxia Li, Fengrong Wang

Front. Biosci. (Landmark Ed) 2025, 30(5), 27094; https://doi.org/10.31083/FBL27094

Gut Barrier, Microbial Metabolites, and Immune Homeostasis in Autoimmune Hepatitis: From Molecular Mechanisms to Strategies

Xintong Zhang, Linyan Wan, Yujiao Zheng, Yaowei Ai

Front. Biosci. (Landmark Ed) 2025, 30(5), 27747; https://doi.org/10.31083/FBL27747

Role of Lysophosphatidic Acid in Neurological Diseases: From Pathophysiology to Therapeutic Implications

Simona Dedoni, Valeria Avdoshina, Maria C. Olianas, Pierluigi Onali

Front. Biosci. (Landmark Ed) 2025, 30(5), 28245; https://doi.org/10.31083/FBL28245

The Critical Role and Therapeutic Potential of the CXCR Family in Skin Diseases

Jin Xu, Chaoyi Wang, Yundong Xu, Bingchen Li, Jianzhou Ye

Front. Biosci. (Landmark Ed) 2025, 30(5), 26759; https://doi.org/10.31083/FBL26759

FCGR1A Alleviates Ischemic Stroke-induced Injury by Promoting Anti-Inflammatory Microglial Polarization via the AMPK–mTOR Signaling Pathway

Meng Liu, Xuhui Fan, Dongya Chen, Huibin Yao, Zhihui Huang, Heng Li, Qing Zhang, Yuqi Wang, Haihan Song, Yufeng Yan

Front. Biosci. (Landmark Ed) 2025, 30(5), 26614; https://doi.org/10.31083/FBL26614