Volume 25, Issue 5 (May 2026)

Wojciech Owecki, Anna Futyma, Olga Kokorniak, Aleksandra Szczech, Bartosz Słowikowski, Joanna Poszwa, Oliwia Szymanowicz, Ulyana Goutor, Paweł P. Jagodziński, Wojciech Kozubski, Jolanta Dorszewska

J. Integr. Neurosci. 2026, 25(5), 50055; https://doi.org/10.31083/JIN50055

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217

Influence of Gait Speed on Spatiotemporal Parameters in Advanced Parkinson’s Disease Following Subthalamic Nucleus Deep Brain Stimulation

Open Access 25 May 2026Original Research

Influence of Gait Speed on Spatiotemporal Parameters in Advanced Parkinson’s Disease Following Subthalamic Nucleus Deep Brain Stimulation

Daniela Sýkorová, Barbora Kolářová, Petr Kolář, David Krahulík, Ahmed Naser Mohamed Afifi, Pavel Otruba, Martin Nevrlý

J. Integr. Neurosci. 2026, 25(5), 48076; https://doi.org/10.31083/JIN48076

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181

Microenvironmental Regulation of Central Nervous System Myelination and Remyelination

Open Access 25 May 2026Review

Microenvironmental Regulation of Central Nervous System Myelination and Remyelination

Yuxuan Wang, Lingzhen Tan, Lin Lao, Xiaomeng Huang, Sheng Zhang, Haitao Sun

J. Integr. Neurosci. 2026, 25(5), 43257; https://doi.org/10.31083/JIN43257

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225

Digital Twins in Neurology Care: Evidence, Limitations, and a Path Forward

Open Access 19 May 2026Opinion

Digital Twins in Neurology Care: Evidence, Limitations, and a Path Forward

Parisa Gazerani

J. Integr. Neurosci. 2026, 25(5), 50563; https://doi.org/10.31083/JIN50563

(This article belongs to the Special Issue Advancing Neurological Care with AI and Digital Twins)

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237

Lactobacillus mucosae Reduces Neuronal Oxidative Stress in Alzheimer’s Disease via the Regulation of CB2 Signaling

Open Access 19 May 2026Original Research

Lactobacillus mucosae Reduces Neuronal Oxidative Stress in Alzheimer’s Disease via the Regulation of CB2 Signaling

Yu Kong, Xinhuang Lv, Yao Yang, Qiyao Li, Conghui Dai, Xiaoou Lin, Jiaming Liu, Jing Li

J. Integr. Neurosci. 2026, 25(5), 48598; https://doi.org/10.31083/JIN48598

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189

Research Progress on How Multimodal Signals Regulate Neuronal Mitochondrial Homeostasis to Affect Diabetic Cognitive Impairment

Open Access 19 May 2026Review

Research Progress on How Multimodal Signals Regulate Neuronal Mitochondrial Homeostasis to Affect Diabetic Cognitive Impairment

Ying Li, Pengwei Zhuang

J. Integr. Neurosci. 2026, 25(5), 45956; https://doi.org/10.31083/JIN45956

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221

Usefulness of Non-Contrast Electron Density Imaging for the Identification of Brain Tissue Changes in Large Vessel Occlusion Acute Ischemic Stroke

Open Access 12 May 2026Short Communication

Usefulness of Non-Contrast Electron Density Imaging for the Identification of Brain Tissue Changes in Large Vessel Occlusion Acute Ischemic Stroke

Santiago de Erausquin, Andres Polania, Gaston A. Rodriguez-Granillo, Pablo Diluca, Carlos Bleise, Pedro Lylyk

J. Integr. Neurosci. 2026, 25(5), 50299; https://doi.org/10.31083/JIN50299

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216

Single-Cell and Integrative Analyses Uncover Therapeutic Potential of RFX1-Mediated Cuproptosis in PitNETs

Open Access 12 May 2026Original Research

Single-Cell and Integrative Analyses Uncover Therapeutic Potential of RFX1-Mediated Cuproptosis in PitNETs

Shuangjian Yang, Changqin Pu, Congcong Deng, Xuexue Bai, Si Wu, Chenxin Tian, Xueyou Xu, Renzhi Wang, Mengqi Chang, Ming Feng

J. Integr. Neurosci. 2026, 25(5), 49669; https://doi.org/10.31083/JIN49669

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208

Tea Polyphenols Protect the Blood–Brain Barrier Structure in the Hippocampus of Early Diabetic Mice by Inhibiting the AGEs–RAGE Pathway

Open Access 12 May 2026Original Research

Tea Polyphenols Protect the Blood–Brain Barrier Structure in the Hippocampus of Early Diabetic Mice by Inhibiting the AGEs–RAGE Pathway

Zhiyong Xu, Yan Liu, Yan Yu

J. Integr. Neurosci. 2026, 25(5), 49065; https://doi.org/10.31083/JIN49065

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240

Understanding Sleep and Memory in the Avian Brain

Open Access 9 May 2026Review

Understanding Sleep and Memory in the Avian Brain

Janie M. Ondracek

J. Integr. Neurosci. 2026, 25(5), 50421; https://doi.org/10.31083/JIN50421

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221

The Neuroprotective Role of a Caspase-1 Inhibitor Against Apoptosis via Inhibition of Glial Hyperactivation in a Mouse Model of Epilepsy

Open Access 9 May 2026Original Research

The Neuroprotective Role of a Caspase-1 Inhibitor Against Apoptosis via Inhibition of Glial Hyperactivation in a Mouse Model of Epilepsy

Hui Cai, Xinran Xu, Xuerui Zhuo, Zhe Liu, Hao Liu, Yiming Sun

J. Integr. Neurosci. 2026, 25(5), 49777; https://doi.org/10.31083/JIN49777

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376

Longitudinal Reorganization of Local Brain Activity Following Acute Basal Ganglia Infarction: Combined Metrics of Amplitude and Dynamics Reveal Neural Substrates Underlying Motor Recovery

Open Access 9 May 2026Original Research

Longitudinal Reorganization of Local Brain Activity Following Acute Basal Ganglia Infarction: Combined Metrics of Amplitude and Dynamics Reveal Neural Substrates Underlying Motor Recovery

Shijian Chen, Jian Zhang, Yayuan Liu, Xuemei Quan, Qiong Yin, Liya Pan, Zhijian Liang

J. Integr. Neurosci. 2026, 25(5), 47725; https://doi.org/10.31083/JIN47725

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247

Metabolic Brain Network Reorganization in Temporal Lobe Epilepsy With Aware or Impaired Awareness Seizures

Open Access 9 May 2026Original Research

Metabolic Brain Network Reorganization in Temporal Lobe Epilepsy With Aware or Impaired Awareness Seizures

Jingke Xiao, Fan Yang, Hanlin Zhang, Jiangyan Liu

J. Integr. Neurosci. 2026, 25(5), 47320; https://doi.org/10.31083/JIN47320

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226

Volume 25, Issue 5 (2026)

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STING Mediates Necroptosis in Hippocampal Neurons of Mice With Sepsis-Associated Encephalopathy

Open Access 26 May 2026Original Research

STING Mediates Necroptosis in Hippocampal Neurons of Mice With Sepsis-Associated Encephalopathy

Xiaofeng Guo, Baocheng Cang, Yunhu Bai, Ding Zhang, You Wu, Tongwen Sun, Xijing Zhang

J. Integr. Neurosci. 2026, 25(5), 50074; https://doi.org/10.31083/JIN50074

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159

“See What I Mean?” Linguistic Digital Markers of Cognitive Decline in Nursing Home Residents

Open Access 26 May 2026Original Research

“See What I Mean?” Linguistic Digital Markers of Cognitive Decline in Nursing Home Residents

Sonja Cecchetti, Andrew T. Duchowski, Marco Cavallo

J. Integr. Neurosci. 2026, 25(5), 49652; https://doi.org/10.31083/JIN49652

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218

Activation of the p62/Keap1/Nrf2 Pathway Protects Against Ferroptosis in Cerebral Ischemia-Reperfusion Injury

Open Access 26 May 2026Original Research

Activation of the p62/Keap1/Nrf2 Pathway Protects Against Ferroptosis in Cerebral Ischemia-Reperfusion Injury

Canwen Liu, Xuanyi Dong, Biao Tang

J. Integr. Neurosci. 2026, 25(5), 48011; https://doi.org/10.31083/JIN48011

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221

Molecular Mechanisms and Potential Biomarkers of Neuropsychiatric Disorders in Parkinson’s Disease

Open Access 25 May 2026Review

Molecular Mechanisms and Potential Biomarkers of Neuropsychiatric Disorders in Parkinson’s Disease

Wojciech Owecki, Anna Futyma, Olga Kokorniak, Aleksandra Szczech, Bartosz Słowikowski, Joanna Poszwa, Oliwia Szymanowicz, Ulyana Goutor, Paweł P. Jagodziński, Wojciech Kozubski, Jolanta Dorszewska