Novel Plasma Biomarkers for Alzheimer’s Disease: Insights from Organotypic Brain Slice and Microcontact Printing Techniques

Sakir Necat Yilmaz, Katharina Steiner, Josef Marksteiner, Klaus Faserl, Bettina Sarg, Christian Humpel

Front. Biosci. (Landmark Ed) 2025, 30(3), 36257; https://doi.org/10.31083/FBL36257

(This article belongs to the Special Issue Exploring Pathomechanisms, Novel Targets, and New Interventions for Neurological and Neuropsychiatric Disorders)

Retraction: Zhu . Resveratrol reverts Streptozotocin-induced diabetic nephropathy. Frontiers in Bioscience (Landmark Edition). 2020; 25: 699–709

Frontiers in Bioscience-Landmark Editorial Office

Front. Biosci. (Landmark Ed) 2025, 30(3), 39230; https://doi.org/10.31083/FBL39230

High-Intensity Interval Training Decreases Circulating HMGB1 in Individuals with Insulin Resistance: Plasma Lipidomics Correlate with Associated Cardiometabolic Benefits

Gabriela Martinez Bravo, Prabu Paramasivam, Gabriella F. Bellissimo, Quiteria Jacquez, Huayu Zheng, Fabiano Amorim, Lara Kovell, Roberto Ivan Mota Alvidrez

Front. Biosci. (Landmark Ed) 2025, 30(3), 31396; https://doi.org/10.31083/FBL31396

Plasma Lipidomics, Gut Microbiota Profile, and Phenotype of Adipose Tissue in an Mouse Model of Plaque Instability

Guanlin Yang, Xin Tan, Qiong Zhai, Yuewu Wang, Xuan Zhang, Pengwei Zhao, Fangyuan Liang, Jingkun Lu, LiLi Bao

Front. Biosci. (Landmark Ed) 2025, 30(3), 27236; https://doi.org/10.31083/FBL27236

CD44 and Its Role in Solid Cancers – A Review: From Tumor Progression to Prognosis and Targeted Therapy

João Martins Gama, Rui Caetano Oliveira

Front. Biosci. (Landmark Ed) 2025, 30(3), 24821; https://doi.org/10.31083/FBL24821

NOL6 Promotes Tumor Progression by Facilitating Cancer Cell-Induced Platelet Aggregation and Angiogenesis in Breast Cancer

Tingting Zhang, Cheng Lu, Mingming Lv, Shengwang Du, Xinjun Wu

Front. Biosci. (Landmark Ed) 2025, 30(3), 25361; https://doi.org/10.31083/FBL25361

Effect of HepG2-Derived Exosome with PDGF-D Knockdown on Transformation of Normal Fibroblasts into Tumor-Associated Fibroblasts in Liver Cancer

Yan-Yan Wu, Liu-Shen-Yan Yu, Han-Yu Zhou, Jun-Chao Xue

Front. Biosci. (Landmark Ed) 2025, 30(3), 26045; https://doi.org/10.31083/FBL26045

Allergy Treatment: A Comprehensive Review of Nanoparticle-based Allergen Immunotherapy

Mabrouk A. Abo-Zaid, Reem M. Elsapagh, Nourhan S. Sultan, Wedad Mawkili, Maysa M. Hegazy, Ahmed H. Ismail

Front. Biosci. (Landmark Ed) 2025, 30(3), 26550; https://doi.org/10.31083/FBL26550

Mast Cells and Microbiome in Health and Disease

Vincenzo Papa, Federica Li Pomi, Mario Di Gioacchino, Rocco Mangifesta, Francesco Borgia, Sebastiano Gangemi

Front. Biosci. (Landmark Ed) 2025, 30(3), 26283; https://doi.org/10.31083/FBL26283

Improvement of RSV-Induced Asthma in Mice: A Study Based on Icariin-Mediated PD-1

Jiayao Fu, Xiaohong Wang

Front. Biosci. (Landmark Ed) 2025, 30(3), 26061; https://doi.org/10.31083/FBL26061

Myeloid-Derived Suppressor Cells: Implications in Cancer Immunology and Immunotherapy

Juan F. Santibanez

Front. Biosci. (Landmark Ed) 2025, 30(3), 25203; https://doi.org/10.31083/FBL25203

Monitoring Autophagy in Human Aging: Key Cell Models and Insights

Tatiana M. Moreno, Jose L. Nieto-Torres, Caroline Kumsta

Front. Biosci. (Landmark Ed) 2025, 30(3), 27091; https://doi.org/10.31083/FBL27091

(This article belongs to the Special Issue Boosting Autophagy to Fight Aging and Age-Related Diseases)

Small Extracellular Vesicles Promote HBV Replication via METTL3–IGF2BP2-Mediated m6A Modification

Jie Zhang, Ling Yu, Xinyu Wu, Wanlong Pan

Front. Biosci. (Landmark Ed) 2025, 30(3), 36291; https://doi.org/10.31083/FBL36291

Emerging Therapeutic Agents and Nanotechnology-Driven Innovations in Psoriasis Management

Tarnjot Kaur, Nikita Hinge, Sudeep Pukale, Mohd Nazam Ansari, Kamal Y. Thajudeen, Mukesh Nandave, Jyoti Upadhyay

Front. Biosci. (Landmark Ed) 2025, 30(3), 27910; https://doi.org/10.31083/FBL27910

An MRI Radiogenomic Signature to Characterize the Transcriptional Heterogeneity Associated with Prognosis and Biological Functions in Glioblastoma

Xiaoqing Zhang, Xiaoyu Zhang, Jie Zhu, Zhuoya Yi, Huijiao Cao, Hailin Tang, Huan Zhang, Guoxian Huang

Front. Biosci. (Landmark Ed) 2025, 30(3), 36348; https://doi.org/10.31083/FBL36348

Ubiquitin Ligases in Control: Regulating NLRP3 Inflammasome Activation

Swarna Beesetti

Front. Biosci. (Landmark Ed) 2025, 30(3), 25970; https://doi.org/10.31083/FBL25970

Leukemia Inhibitory Factor Attenuates Hypoxic–Ischemic White Matter Injury via NLRP3 Inflammasome Activity Suppressing Through the Nrf2/HO-1 Pathway

Liang Huo, Xueyan Liu, Hua Wang

Front. Biosci. (Landmark Ed) 2025, 30(3), 36630; https://doi.org/10.31083/FBL36630

(This article belongs to the Special Issue Regulated Cell Death and Disease)

Interplay Between Polyphenols and Autophagy: Insights From an Aging Perspective

Alejandro Ponce-Mora, Nicolle Andrea Salazar, Alicia Domenech-Bendaña, Antonella Locascio, Eloy Bejarano, Lucia Gimeno-Mallench

Front. Biosci. (Landmark Ed) 2025, 30(3), 25728; https://doi.org/10.31083/FBL25728

(This article belongs to the Special Issue Boosting Autophagy to Fight Aging and Age-Related Diseases)

Transcription Factor FOSL1 Promotes Cisplatin Resistance in Non-Small Cell Lung Cancer Cells by Modulating the Wnt3a/β-Catenin Signaling through Upregulation of PLIN3 Expression

Wanning Tong, Jianjun Sun, Bin Shen, Yaohua Hu, Chenxing Wang, Min Rao, Jin Li, Delin Xia, Jiagui Dong, Hong Wang, Dongmei Zhu, Haibo Wu, Zhigang Cai

Front. Biosci. (Landmark Ed) 2025, 30(3), 26898; https://doi.org/10.31083/FBL26898

3D Bioprinting of Cultivated Meat Followed by the Development of a Fine-Tuned YOLO Model for the Detection and Counting of Lipoblasts, Fibroblasts, and Myogenic Cells

Rozaliia Nabiullina, Sergey Golovin, Evgeniya Kirichenko, Mikhail Petrushan, Alexander Logvinov, Marya Kaplya, Darya Sedova, Stanislav Rodkin

Front. Biosci. (Landmark Ed) 2025, 30(3), 36266; https://doi.org/10.31083/FBL36266

Growth Arrest-specific 1 Inhibits Keap1/Nrf2 Signaling Transduction in the Activation of the Ferroptosis Program in Retinal Müller Cells

Rongfeng Dai, Yu Qian, Siqi Liu, Xi Zou, Shanshan Sun, Zhuo Sun

Front. Biosci. (Landmark Ed) 2025, 30(3), 27954; https://doi.org/10.31083/FBL27954

Comparative Study of Structural and Functional Rearrangements in Skeletal Muscle Mitochondria of SOD1-G93A Transgenic Mice at Pre-, Early-, and Late-Symptomatic Stages of ALS Progression

Natalia V. Belosludtseva, Anna I. Ilzorkina, Mikhail V. Dubinin, Irina B. Mikheeva, Konstantin N. Belosludtsev

Front. Biosci. (Landmark Ed) 2025, 30(3), 28260; https://doi.org/10.31083/FBL28260

Chronic Inflammation to Cancer: The Impact of Oxidative Stress on DNA Methylation

Olivia M. Damiano, Aaron J. Stevens, Diane N. Kenwright, Annika R. Seddon

Front. Biosci. (Landmark Ed) 2025, 30(3), 26142; https://doi.org/10.31083/FBL26142

Significance of Macrophage-Mediated Inflammatory Response in Ocular Inflammatory Complications

Sara McMahon, Tori Spector, Kota V Ramana

Front. Biosci. (Landmark Ed) 2025, 30(3), 26698; https://doi.org/10.31083/FBL26698

Dapagliflozin Attenuates Myocardial Inflammation and Apoptosis after Coronary Microembolization in Rats by Regulating the SIRT1/NF-κB Signaling Pathway

Tao Li, Chang-Jun Luo, Ze-Qiang Yi, Lang Li

Front. Biosci. (Landmark Ed) 2025, 30(3), 27082; https://doi.org/10.31083/FBL27082

Potential Genetic Approach to Specific Primary Immunodeficiencies: Which Perspectives?

Giuseppe Murdaca, Francesca Paladin, Sebastiano Gangemi

Front. Biosci. (Landmark Ed) 2025, 30(3), 36795; https://doi.org/10.31083/FBL36795

Possible Role of Platelets in the Development and Progression of Non-Alcoholic Fatty Liver Disease

Anna F. Sheptulina, Ekaterina O. Liusina, Olga A. Zlobovskaya, Anton R. Kiselev, Oxana M. Drapkina

Front. Biosci. (Landmark Ed) 2025, 30(3), 26748; https://doi.org/10.31083/FBL26748

Revisiting the Role of Platelet-Activating Factor in COVID-19-Induced Cardiovascular Complications

Smaragdi Antonopoulou

Front. Biosci. (Landmark Ed) 2025, 30(3), 36981; https://doi.org/10.31083/FBL36981

NO Pain! No Cancer? The Crosstalk Between Nociception, ROS, and Cancer Development

Tzu-Yin Chen, Tohru Yoshioka, Wen-Li Hsu

Front. Biosci. (Landmark Ed) 2025, 30(3), 31328; https://doi.org/10.31083/FBL31328

(This article belongs to the Special Issue Mitochondria Targeting Strategies for Treatment of Human Diseases)

A Quality by Design (QbD) Project of Human Dermal Fibroblast and its Therapeutic Effects on Managing Degenerative Intervertebral Disc Fibrosis in Rabbit and Cynomolgus Monkey

Li Zhou, Hongsheng Li, Chen Chen, Hao Yang, Guicheng Zhang, Qin Zhang, Mengnan Wen, Lei Shi, Tong Xing, Ming Fan, An Qin, Jie Zhao, Shen’ao Zhou

Front. Biosci. (Landmark Ed) 2025, 30(3), 28062; https://doi.org/10.31083/FBL28062

Historical View and Some Unsolved Problems in Red Blood Cell Membrane Research

Ingolf Bernhardt, Lars Kaestner

Front. Biosci. (Landmark Ed) 2025, 30(3), 25331; https://doi.org/10.31083/FBL25331

(This article belongs to the Special Issue Red Blood Cell in Health and Disease)

Scutellarin Attenuates Pro-Inflammatory Foam Cell Formation and Facilitates M2 Polarization in Microglia during Copper Homeostasis Imbalance via the MAPK Signaling Pathway

Qiting Zhao, Lingyi Chen, Yantuanjin Ma, Shufen Wang

Front. Biosci. (Landmark Ed) 2025, 30(3), 36255; https://doi.org/10.31083/FBL36255

Loss of Atoh8 Affects Neurocranial and Axial Skeleton Development in Zebrafish

Ninfa Fragale, Satya Srirama Karthik Divvela, Victoria Clare Williams-Ward, Beate Brand-Saberi

Front. Biosci. (Landmark Ed) 2025, 30(3), 26806; https://doi.org/10.31083/FBL26806

CD47 Contributes to the Proliferation of Breast Cancer

Junbin Wang, Xia Wu, Xuejian Liu, Ying Xu

Front. Biosci. (Landmark Ed) 2025, 30(3), 28210; https://doi.org/10.31083/FBL28210

cGAS/STING/NLRP3 Signaling Pathway-Mediated Pyroptosis in Hypertrophic Cardiomyopathy Radiotherapy

Huiyang Li, Xin Wang, Xinping Luo, Haiming Shi, Jian Li

Front. Biosci. (Landmark Ed) 2025, 30(3), 26084; https://doi.org/10.31083/FBL26084