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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 5 Issue 3 2000
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- ArticleYeast perspectives on HIV-1 VPRYuqi Zhao, Robert T. ElderFront. Biosci. (Landmark Ed) 2000, 5(3), 905–916; https://doi.org/10.2741/zhao6Downloads18Citations10Views
- ArticleCell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycleBrian T. Zafonte, James Hulit, Derek F. Amanatullah, Chris Albanese, ... Richard G. PestellFront. Biosci. (Landmark Ed) 2000, 5(3), 938–961; https://doi.org/10.2741/zafonte(This article belongs to the Special Issue Cell cycle dysregulation in disease)46Downloads37Citations54Views
- ArticleBruton tyrosine kinase (BTK) in X-linked agammaglobulinemia (XLA)Mauno Vihinen, Pekka T. Mattsson, C. I. Edvard SmithFront. Biosci. (Landmark Ed) 2000, 5(3), 917–928; https://doi.org/10.2741/vihinen85Downloads24Citations63Views
- ArticleCaveolins in cholesterol trafficking and signal transduction: implications for human diseaseAmnon Schlegel, Richard G. Pestell, Michael P. LisantiFront. Biosci. (Landmark Ed) 2000, 5(3), 929–937; https://doi.org/10.2741/schlegel(This article belongs to the Special Issue Cell cycle dysregulation in disease)9Downloads39Citations14Views
- ArticleImmune regulation by CD40-CD40-l interactions - 2; Y2K updateCees van KootenFront. Biosci. (Landmark Ed) 2000, 5(3), 880–893; https://doi.org/10.2741/kooten15Downloads29Citations29Views
- ArticleThe physiology and psychology of selective attention to touchHeidi Johansen-Berg, Donna M LloydFront. Biosci. (Landmark Ed) 2000, 5(3), 894–904; https://doi.org/10.2741/berg(This article belongs to the Special Issue Congition and attention)8Downloads26Citations29Views
- ArticleProtein stability in extremophilic archaeaRoberto Scandurra, Valerio Consalvi, Roberta Chiaraluce, Laura Politi, Paul C. EngelFront. Biosci. (Landmark Ed) 2000, 5(3), 787–795; https://doi.org/10.2741/scan(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)6Downloads13Citations15Views
- ArticleOsmoadaptation and osmoregulation in archaeaMary F. RobertsFront. Biosci. (Landmark Ed) 2000, 5(3), 796–812; https://doi.org/10.2741/roberts(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)31Downloads39Citations36Views
- ArticlePlasmalemmal transport of magnesium in excitable cellsHector Rasgado-Flores, Hugo Gonzalez-SerratosFront. Biosci. (Landmark Ed) 2000, 5(3), 866–879; https://doi.org/10.2741/rasgado3Downloads7Citations10Views
- ArticleMolecular mechanisms regulating myogenic determination and differentiationRobert L.S. Perry, Michael A. RudnickFront. Biosci. (Landmark Ed) 2000, 5(3), 750–767; https://doi.org/10.2741/perry(This article belongs to the Special Issue Cellular and molecular aspects of muscle pathology)82Downloads154Citations570Views
- Article
Archaeal peptidyl prolyl cis-trans isomerases (PPIases)
Tadashi Maruyama, Masahiro FurutaniFront. Biosci. (Landmark Ed) 2000, 5(3), 821–836; https://doi.org/10.2741/maruyama(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)13Downloads15Citations26Views - ArticleStressors, stress and survival: overviewEverly Conway de Macario, Alberto J. L. MacarioFront. Biosci. (Landmark Ed) 2000, 5(3), 780–786; https://doi.org/10.2741/A550(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)13Downloads30Citations21Views
- ArticleProteasomes in the archaea: from structure to functionJulie A. Maupin-Furlow, Heather L. Wilson, Steven J. Kaczowka, Mark S. OuFront. Biosci. (Landmark Ed) 2000, 5(3), 837–865; https://doi.org/10.2741/furlow(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)28Downloads19Citations41Views
- ArticleOxygen: friend or foe? Archaeal superoxide dismutases in the protection of intra- and extracellular oxidative stressRaffaele Cannio, Gabriella Fiorentino, Alessandra Morana, Mosè Rossi, Simonetta BartolucciFront. Biosci. (Landmark Ed) 2000, 5(3), 768–779; https://doi.org/10.2741/cannio(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)14Downloads39Citations23Views
- ArticleAdaptations of the archaeal cell membrane to heat stressSonja-Verena Albers, Jack L.C.M. van de Vossenberg, Arnold J.M. Driessen, Wil N. KoningsFront. Biosci. (Landmark Ed) 2000, 5(3), 813–820; https://doi.org/10.2741/albers(This article belongs to the Special Issue Anti-stress mechanisms in archaea: implications for biology and medicine)130Downloads64Citations687Views
- ArticleRegulation of intracellular free magnesium in central nervous system injuryRobert Vink, Ibolja CernakFront. Biosci. (Landmark Ed) 2000, 5(3), 656–665; https://doi.org/10.2741/vink(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)12Downloads37Citations18Views
- ArticleSpecificity in the cAMP/PKA signaling pathway. Differential expression,regulation, and subcellular localization of subunits of PKABjørn S Skålhegg, Kjetil TaskenFront. Biosci. (Landmark Ed) 2000, 5(3), 678–693; https://doi.org/10.2741/skalhegg(This article belongs to the Special Issue Signaling through protein kinase C)148Downloads159Citations153Views
- ArticleMagnesium transport in the gastrointestinal tractM. Schweigel, H. MartensFront. Biosci. (Landmark Ed) 2000, 5(3), 666–677; https://doi.org/10.2741/schweigel(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)52Downloads33Citations56Views
- ArticleRegulation of cellular magnesiumAndrea M.P. Romani, Antonio ScarpaFront. Biosci. (Landmark Ed) 2000, 5(3), 720–734; https://doi.org/10.2741/romani(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)57Downloads201Citations67Views
- ArticleEpithelial magnesium transport and regulation by the kidneyGary A. Quamme, Christian de RouffignacFront. Biosci. (Landmark Ed) 2000, 5(3), 694–711; https://doi.org/10.2741/quamme(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)25Downloads62Citations21Views
- ArticleRole and regulation of apoptotic cell death in the kidney. Y2K updateAlberto Ortiz, Corina Lorz, Marina P. Catalan, Pilar Justo, Jesús EgidoFront. Biosci. (Landmark Ed) 2000, 5(3), 735–749; https://doi.org/10.2741/ortiz7Downloads10Citations17Views
- ArticleRenal handling of magnesium in fish: from whole animal to brush border membrane vesiclesKlaus W. BeyenbachFront. Biosci. (Landmark Ed) 2000, 5(3), 712–719; https://doi.org/10.2741/beyenbach(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)14Downloads13Citations21Views
- ArticleIntracellular magnesium: transport and regulation in epithelial secretory cellsMaria D. Yago, Mariano Mañas, Jaipaul SinghFront. Biosci. (Landmark Ed) 2000, 5(3), 602–618; https://doi.org/10.2741/yago(This article belongs to the Special Issue Magnesium and cell proliferation and differentiation)19Downloads22Citations27Views
- ArticleBiosynthesis and regulation of expression of proteoglycansNancy B. SchwartzFront. Biosci. (Landmark Ed) 2000, 5(3), 649–655; https://doi.org/10.2741/A54017Downloads50Citations20Views
- ArticleControl of vascular smooth muscle cell growth by cyclin-dependent kinase inhibitory proteins and its implication in cardiovascular diseaseSilvia M. Sanz-González, Enric Poch, Ignacio Pérez-Roger, Antonio Díez-Juan, ... Vicente AndrésFront. Biosci. (Landmark Ed) 2000, 5(3), 619–628; https://doi.org/10.2741/sanz(This article belongs to the Special Issue Eukaryotic cell cycle control)6Downloads19Citations11Views
- ArticleThe metabolism of quinone-containing alkylating agents: free radical production and measurementPeter L. GutierrezFront. Biosci. (Landmark Ed) 2000, 5(3), 629–638; https://doi.org/10.2741/gutier(This article belongs to the Special Issue Mechanisms of action of quinone-containing alkylating agents)20Downloads34Citations33Views
- ArticleMechanisms of action of quinone-containing alkylating agents. I: NQO1-directed drug developmentHoward D. Beall, Shannon L. WinskiFront. Biosci. (Landmark Ed) 2000, 5(3), 639–648; https://doi.org/10.2741/beall(This article belongs to the Special Issue Mechanisms of action of quinone-containing alkylating agents)10Downloads31Citations17Views
- ArticleClinical studies of antisense therapy in cancerAlan R. Yuen, Branimir I. SikicFront. Biosci. (Landmark Ed) 2000, 5(3), 588–593; https://doi.org/10.2741/yuen(This article belongs to the Special Issue Anti-sense therapeutics)10Downloads20Citations26Views
- ArticleCell cycle implications in the pathogenesis of rheumatoid arthritisMichael V. Volin, Alisa E. KochFront. Biosci. (Landmark Ed) 2000, 5(3), 594–601; https://doi.org/10.2741/volin(This article belongs to the Special Issue Cell cycle dysregulation in disease)2Downloads9Citations15Views
- ArticleCaloric restriction and immunosenescence: a current perspectiveMohammad A. PahlavaniFront. Biosci. (Landmark Ed) 2000, 5(3), 580–587; https://doi.org/10.2741/pahlavani15Downloads22Citations12Views
- ArticleProtein oxidation and age-dependent alterations in calcium homeostasisThomas C. Squier, Diana J. BigelowFront. Biosci. (Landmark Ed) 2000, 5(3), 504–526; https://doi.org/10.2741/squier20Downloads94Citations30Views
- ArticlePotential nuclease-based strategies for HIV gene therapySanjeev Singwi, Sadhna JoshiFront. Biosci. (Landmark Ed) 2000, 5(3), 556–579; https://doi.org/10.2741/singwi5Downloads9Citations17Views
- ArticleCell cycle control in growth plate chondrocytesPhyllis LuValle, Frank BeierFront. Biosci. (Landmark Ed) 2000, 5(3), 493–503; https://doi.org/10.2741/luvalle(This article belongs to the Special Issue Cell cycle dysregulation in disease)10Downloads16Citations14Views
- ArticleCurrent developments and future prospects for HIV gene therapy using interfering RNA-based strategiesBetty Lamothe, Sadhna JoshiFront. Biosci. (Landmark Ed) 2000, 5(3), 527–555; https://doi.org/10.2741/lamothe(This article belongs to the Special Issue New and emerging targets for antiviral therapy)3Downloads12Citations10Views
- Article
The development and biology of bradyzoites of Toxoplasma gondii
Louis M. Weiss, Kami KimFront. Biosci. (Landmark Ed) 2000, 5(3), 391–405; https://doi.org/10.2741/weiss48Downloads118Citations101Views - ArticleTumor suppressor p53: regulation and functionKumaravel Somasundaram, Wafik S. El-DeiryFront. Biosci. (Landmark Ed) 2000, 5(3), 424–437; https://doi.org/10.2741/somasund(This article belongs to the Special Issue Eukaryotic cell cycle control)50Downloads96Citations63Views
- ArticleMechanisms of interferon-induced cell cycle arrestOlle Sangfelt, Sven Erickson, Dan GranderFront. Biosci. (Landmark Ed) 2000, 5(3), 479–487; https://doi.org/10.2741/sangfelt(This article belongs to the Special Issue Cell cycle dysregulation in disease)90Downloads50Citations129Views
- ArticleCell cycle molecules and diseases of the cardiovascular systemStefka B. Petkova, Anthony Ashton, Boumediene Bouzahzah, Huan Huang, ... Herbert B. TanowitzFront. Biosci. (Landmark Ed) 2000, 5(3), 452–460; https://doi.org/10.2741/petkova(This article belongs to the Special Issue Cell cycle dysregulation in disease)24Downloads21Citations37Views
- ArticleReprogramming erythroleuekmia cells to terminal differentiation and terminal cell divisionIgor Matushansky, Farshid Radparvar, Natasha Rekhtman, Arthur SkoultchiFront. Biosci. (Landmark Ed) 2000, 5(3), 488–492; https://doi.org/10.2741/matushan(This article belongs to the Special Issue Carbohydrates in immunology evolution of the immune system in particular MHC)2Downloads11Citations9Views
- ArticleThe neurobiology of attention-deficit hyperactivity disorderJessica Himelstein, Kurt P. Schulz, Jeffrey H. Newcorn, Jeffrey M. HalperinFront. Biosci. (Landmark Ed) 2000, 5(3), 461–478; https://doi.org/10.2741/himelste(This article belongs to the Special Issue Congition and attention)34Downloads64Citations78Views
- ArticleBETA 2 integrin signaling in leukocytesKarim Dib, Tommy AnderssonFront. Biosci. (Landmark Ed) 2000, 5(3), 438–451; https://doi.org/10.2741/pathology(This article belongs to the Special Issue Integrins, cell migration and extracellular matrix)15Downloads24Citations29Views
- ArticleProtein kinase C-mediated regulation of the cell cycleJennifer D. BlackFront. Biosci. (Landmark Ed) 2000, 5(3), 406–423; https://doi.org/10.2741/black(This article belongs to the Special Issue Eukaryotic cell cycle control)19Downloads82Citations33Views
- ArticleCell-cycle dysregulation and the molecular mechanisms of prostate cancerDerek F. Amanatullah, Anne T. Reutens, Brian T. Zafonte, Maofu Fu, ... Richard G. PestellFront. Biosci. (Landmark Ed) 2000, 5(3), 372–390; https://doi.org/10.2741/amanatullah(This article belongs to the Special Issue Cell cycle dysregulation in disease)10Downloads36Citations17Views
- ArticleLuteinizing hormone receptor mutations in disorders of sexual development and cancerShao-Ming Wu, Ellen Werber Leschek, Owen M. Rennert, Wai-Yee ChanFront. Biosci. (Landmark Ed) 2000, 5(3), 343–352; https://doi.org/10.2741/wu(This article belongs to the Special Issue Genetic diseases)21Downloads36Citations218Views
- ArticleProgress in molecular genetics of autosomal dominant polycystic kidney diseaseMarie Trudel, Richard GuillaumeFront. Biosci. (Landmark Ed) 2000, 5(3), 312–320; https://doi.org/10.2741/trudel3Downloads12Views
- ArticleGenetics of Carney complex and related familial lentiginoses, and other multiple tumor syndromesConstantine A. StratakisFront. Biosci. (Landmark Ed) 2000, 5(3), 353–366; https://doi.org/10.2741/stratakis(This article belongs to the Special Issue Genetic diseases)11Downloads22Citations21Views
- ArticleMolecular genetics of holoprosencephalyLuisa Nanni, Robert L. Schelper, Maximilian MuenkeFront. Biosci. (Landmark Ed) 2000, 5(3), 334–342; https://doi.org/10.2741/nanni27Downloads23Citations26Views
- ArticleMolecular genetics of peroxisomal disordersHugo W. MoserFront. Biosci. (Landmark Ed) 2000, 5(3), 298–306; https://doi.org/10.2741/moser(This article belongs to the Special Issue Genetic diseases)5Downloads20Citations17Views
- ArticleSpongy degeneration of the brain, Canavan disease: biochemical and molecular findingsReuben Matalon, Kimberlee Michals-MatalonFront. Biosci. (Landmark Ed) 2000, 5(3), 307–311; https://doi.org/10.2741/matalon(This article belongs to the Special Issue Genetic diseases)41Downloads21Citations55Views
- ArticleCyclin D1 in parathyroid diseaseSanjay M. Mallya, Andrew ArnoldFront. Biosci. (Landmark Ed) 2000, 5(3), 367–371; https://doi.org/10.2741/mallya(This article belongs to the Special Issue Cell cycle dysregulation in disease)16Downloads34Citations36Views
- ArticleRecent advances in the understanding of genetic causes of congenital heart defectsBruce D. GelbFront. Biosci. (Landmark Ed) 2000, 5(3), 321–333; https://doi.org/10.2741/gelb(This article belongs to the Special Issue Genetic diseases)5Downloads2Citations15Views
- ArticleInteractions of HIV-1 NEF with cellular signal transducing proteinsG. Herma Renkema, Kalle SakselaFront. Biosci. (Landmark Ed) 2000, 5(3), 268–283; https://doi.org/10.2741/renkema(This article belongs to the Special Issue New and emerging targets for antiviral therapy)8Downloads124Citations46Views
- ArticleMitogen-activated signaling and cell cycle regulation in airway smooth muscleKristen Page, Marc B. HershensonFront. Biosci. (Landmark Ed) 2000, 5(3), 258–267; https://doi.org/10.2741/page(This article belongs to the Special Issue Cell cycle dysregulation in disease)5Downloads21Citations11Views
- ArticleModulations of primary visual cortex activity representing attentive and conscious scene perceptionVictor A.F. Lamme, Henk SpekreijseFront. Biosci. (Landmark Ed) 2000, 5(3), 232–243; https://doi.org/10.2741/lamme(This article belongs to the Special Issue Congition and attention)12Downloads26Citations27Views
- ArticleVisual attention and agingKaren E. Groth, Philip A. AllenFront. Biosci. (Landmark Ed) 2000, 5(3), 284–297; https://doi.org/10.2741/groth(This article belongs to the Special Issue Congition and attention)60Downloads21Citations85Views
- ArticleCell cycle regulation and RNA polymerase IIDavid B. Bregman, Richard G. Pestell, Vincent J. KiddFront. Biosci. (Landmark Ed) 2000, 5(3), 244–257; https://doi.org/10.2741/bregman(This article belongs to the Special Issue Cell cycle dysregulation in disease)37Downloads46Citations39Views
- ArticleHuman T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemiaJing Yao, Brian WigdahlFront. Biosci. (Landmark Ed) 2000, 5(3), 138–168; https://doi.org/10.2741/yao7Downloads26Citations16Views
- ArticleBacterial resistance to aminoglycosides and beta-lactams: the Tn1331 transposon paradigmMarcelo E. TolmaskyFront. Biosci. (Landmark Ed) 2000, 5(3), 20–29; https://doi.org/10.2741/tolmasky(This article belongs to the Special Issue Bacterial resistance to aminoglycoside and beta-lactam antibiotics: molecular genetics and dissemination)15Downloads8Citations35Views
- ArticleRole of pRB dephosphorylation in cell cycle regulationSama Tamrakar, Ethel Rubin, John W. LudlowFront. Biosci. (Landmark Ed) 2000, 5(3), 121–137; https://doi.org/10.2741/tamrakar(This article belongs to the Special Issue Cellular functions of protein phosphatases)58Downloads71Citations45Views
- ArticleGenetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implicationsJustin S. Smith, Robert B. JenkinsFront. Biosci. (Landmark Ed) 2000, 5(3), 213–231; https://doi.org/10.2741/smith(This article belongs to the Special Issue Encyclopedia of neuro-oncology)14Downloads105Citations68Views
- ArticleTheoretical and experimental approaches to design effective antisense oligonucleotidesGeorg SczakielFront. Biosci. (Landmark Ed) 2000, 5(3), 194–201; https://doi.org/10.2741/sczakiel(This article belongs to the Special Issue Anti-sense therapeutics)8Downloads12Citations10Views
- ArticleCell cycle control of pancreatic beta cell proliferationSushil G. Rane, E. Premkumar ReddyFront. Biosci. (Landmark Ed) 2000, 5(3), 1–19; https://doi.org/10.2741/rane(This article belongs to the Special Issue Eukaryotic cell cycle control)27Downloads27Citations17Views
- ArticleVisual search: bottom-up or top-down?Gargi A. Patel, K. SathianFront. Biosci. (Landmark Ed) 2000, 5(3), 169–193; https://doi.org/10.2741/A503(This article belongs to the Special Issue Congition and attention)17Downloads12Citations33Views
- ArticleCentripetal versus centrifugal bias in visual line bisection: focusing attention on two hypothesesMark E. McCourt, Matt Garlinghouse, Jessica SlaterFront. Biosci. (Landmark Ed) 2000, 5(3), 58–71; https://doi.org/10.2741/A496(This article belongs to the Special Issue Congition and attention)2Downloads37Citations12Views
- ArticleThe control of mitosisMary L. Hixon, Antonio GualbertoFront. Biosci. (Landmark Ed) 2000, 5(3), 50–57; https://doi.org/10.2741/hixon(This article belongs to the Special Issue Eukaryotic cell cycle control)27Downloads8Citations74Views
- ArticleCellular and molecular basis of beta-amyloid precursor protein metabolismJeffrey P. Greenfield, Rachel S. Gross, Gunnar K. Gouras, Huaxi XuFront. Biosci. (Landmark Ed) 2000, 5(3), 72–83; https://doi.org/10.2741/greenfield6Downloads36Citations14Views
- ArticleThe development of auditory attention in childrenHilary Gomes, Sophie Molholm, Christopher Christodoulou, Walter Ritter, Nelson CowanFront. Biosci. (Landmark Ed) 2000, 5(3), 108–120; https://doi.org/10.2741/gomes(This article belongs to the Special Issue Congition and attention)81Downloads62Citations123Views
- ArticleNeurophysiological mechanisms of auditory selective attention in humansMarie-Helene Giard, Alexandra Fort, Yolande Mouchetant-Rostaing, Jacques PernierFront. Biosci. (Landmark Ed) 2000, 5(3), 84–94; https://doi.org/10.2741/giard(This article belongs to the Special Issue Congition and attention)52Downloads66Citations85Views
- ArticlePathogenesis and treatment of HIV-1 infection: recent developments (Y2K update)Stephen Dewhurst, Ramothea L.W. da Cruz, Linda WhetterFront. Biosci. (Landmark Ed) 2000, 5(3), 30–49; https://doi.org/10.2741/A494(This article belongs to the Special Issue New and emerging targets for antiviral therapy)6Downloads4Citations7Views
- ArticleMultiple facets of sialomucin complex/MUC4, a membrane mucin and erbb2 ligand, in tumors and tissues (Y2K update)Kermit L. Carraway, Shari A. Price-Schiavi, Masanobu Komatsu, Nebila Idris, ... Coralie A. CarrawayFront. Biosci. (Landmark Ed) 2000, 5(3), 95–107; https://doi.org/10.2741/carraway8Downloads20Citations13Views
- ArticleSelectively attending to auditory objectsClaude Alain, Stephen R ArnottFront. Biosci. (Landmark Ed) 2000, 5(3), 202–212; https://doi.org/10.2741/alain(This article belongs to the Special Issue Congition and attention)37Downloads93Citations90Views