New Insights into Antitumor Activity in Breast Cancer

Dear Colleagues,

Breast cancer is one of the most common oncological diseases affecting women. Hormone therapy is a commonly used strategy to treat breast cancer due to the estrogen-dependent nature of many breast cancer subtypes. In the most aggressive subtype, triple-negative breast cancer, treatment with hormone therapy or with HER2 inhibitors is ineffective. A better understanding of the biological heterogeneity of breast cancer is therefore needed in order to discover new therapeutic targets and to develop more effective and individualized treatments. Special attention must also be paid to the emergence of drug resistance, which is a major challenge to the successful development of targeted therapy for different molecular subtypes of breast cancer. This includes the use of more advanced methods to identify changes induced by drug treatment that may be related to compensatory signaling pathways in drug-resistant cancer cells.

This Special Issue will focus on current approaches and emerging novel strategies for local and systemic therapy of the major molecular subtypes of breast cancer. Clinical, molecular and biochemical studies that aim to expand our understanding of this tumor and its successful treatment are welcome.

Prof.  Rumiana Tzoneva

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.