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Bioactive Phytochemicals and Botanicals in Health and Disease

Submission deadline: 31 December 2022
Special Issue Editor
Marcello Iriti, PhD
Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy
Interests: bioactive phytochemicals; bioavailability of phytochemicals; funcitonal foods; nutraceuticals; medicinal plants; herbal remedies; mediterranean diet; traditional diets; ethnonutrition; ethnopharmacology; food security; food safety
Special Issue and Collections in IMR journals
Special Issue Information

Dear Colleagues,

In the last decades, a huge amount of preclinical (i.e. in vitro and in vivo) studies indicated that phytochemicals and plant extracts exert a plethora of biological and pharmacological activities in cell cultures and animal models, though the evidence in humans is less substantiated and still fragmentary. Nowadays, we know that bioactive phytochemicals and herbal medicines possess antimicrobial, anti-inflammatory, antioxidant/prooxidant, cytotoxic and immunomodulating activities, inter alia, which make them promising cardioprotective, neuroprotective, anticancer, antidiabetes, antiobesity and antiaging agents. However, these natural products appear to be more effective in prevention than in treatment of chronic-degenerative diseases. This is the case of healthy diets rich in plant foods. Not least, phytochemicals can be used as adjuvants in association with conventional therapies in order to improve their efficacy, reduce their adverse effects, decrease the risk of selecting resistant microbial strains or cancer cells or even revert resistance (including radioresistance).

Within this broad context, this Special Issue welcomes contributes focusing on bioactive phytochemicals and botanicals, with an emphasis on their health-promoting effects. Therefore, we invite investigators to submit both original research and review articles that explore all these aspects.

Assoc. Prof. Dr. Marcello Iriti

Guest Editor

Functional Foods
Medicinal Plants
Herbal Remedies
Plant Secondary Metabolites
ADME (adsorption
Non-communicable Diseases
Cancer Chemoprevention
Infectious Diseases
Antimicrobial Resistance
Anti-obesity agents
Antidiabetic agents
One Health
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

Published Paper (3 Papers)
Open Access Original Research
Therapeutic Efficacy of Polyphenol-Rich Fraction of Boesenbergia rotunda in Diabetic Rats: A Focus on Hypoglycemic, Antihyperlipidemic, Carbohydrate Metabolism, Antioxidant, Anti-Inflammatory and Pancreato-Protective Activities
Ting Wang, Chunhong Liu, Shouhong Shu, Qiu Zhang, Opeyemi Joshua Olatunji
Front. Biosci. (Landmark Ed) 2022, 27(7), 206; (registering DOI)
(This article belongs to the Special Issue Bioactive Phytochemicals and Botanicals in Health and Disease)
Open Access Review
A Review on Tradescantia: Phytochemical Constituents, Biological Activities and Health-Promoting Effects
Monica Butnariu, Cristina Quispe, Jesús Herrera-Bravo, Álvaro Fernández-Ochoa, ... Javad Sharifi-Rad
Front. Biosci. (Landmark Ed) 2022, 27(6), 197;
(This article belongs to the Special Issue Bioactive Phytochemicals and Botanicals in Health and Disease)
Open Access Original Research
Effect οf elicitοrs οn cell suspensiοn culture οf Urginea maritima L. tοwards prοductiοn οf prοscillaridin A
Heba Shahin, Atef A. El-Hela, Mahmοud I. Nasr, Ghada M. Nasr
Front. Biosci. (Landmark Ed) 2022, 27(2), 45;
(This article belongs to the Special Issue Bioactive Phytochemicals and Botanicals in Health and Disease)
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