IMR Press / FBL / Volume 17 / Issue 3 / DOI: 10.2741/3967

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Function of the INO80 chromatin remodeling complex in DNA replication
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1 Department of Carcinogenesis, Science Park Research Division, MD Anderson Cancer Center, Smithville, Texas 78957, USA
Academic Editor:Min-Hao Kuo
Front. Biosci. (Landmark Ed) 2012, 17(3), 970–975;
Published: 1 January 2012
(This article belongs to the Special Issue Chromatin and cell cycle)

ATP-dependent chromatin remodeling complexes are involved in several nuclear processes. In particular the INO80 remodeling complex is an essential factor during transcription and DNA repair. Recently, several labs have described a novel role for INO80 during DNA replication. Moreover, Falbo et al. have presented evidence linking INO80's activities to the DNA damage tolerance pathways during replication (1). In this review we will discuss and integrate the results obtain by these various research groups to describe a novel role for INO80 in DNA replication.

DNA replication
Damage Tolerance Pathway
Chromatin Remodeling Complex
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