IMR Press / FBL / Volume 26 / Issue 5 / DOI: 10.52586/4921
Open Access Review
Microorganisms and cardiovascular diseases: importance of gut bacteria
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1 Department of Life Sciences (DLS), School of Environment and Life Sciences (SELS), Independent University, Bangladesh (IUB), 1212 Dhaka, Bangladesh
2 Department of Cardiology, Kolling Institute of Medical Research, Northern Sydney Local Health District, St Leonards, 2065 NSW, Australia
3 Sydney Medical School Northern, University of Sydney, 2006 NSW, Australia
*Correspondence: (Rashed Noor)
Front. Biosci. (Landmark Ed) 2021, 26(5), 22–28;
Submitted: 28 August 2019 | Accepted: 25 November 2020 | Published: 30 April 2021
(This article belongs to the Special Issue Novel therapeutic approaches to cardiovascular diseases)
Copyright: © 2021 The Author(s). Published by BRI.
This is an open access article under the CC BY 4.0 license (

Cardiovascular diseases including myocardial infarctions, myocarditis, strokes, coronary artery disease, chronic granulomatous disease, atherosclerotic cardiovascular disease, etc. can be regarded as the severe health trouble round the globe. The reasons behind the heart related complications have been well chalked our so far. Interestingly, along with the non-infectious reasons, an array of bacteria, fungi, parasites and viruses is known to cause different types of heart complications. Unfortunately, the role of microorganisms in inducing heart diseases is not that much known by the mass community in the underdeveloped and even in the developing countries over the world. However, among the microorganisms causing heart diseases, the multifaceted bionetwork by the gut microorganisms especially drew the interests of microbiologists. The impairment of cardiac membrane, the metabolic malfunction of heart, and imbalance in the functionality of the immune cells by the alternation in the composition of gut microorganisms are currently not unknown. Present review outlined the onset of heart diseases caused by the gut microflora in a simple way which would be important in public health regard.

Cardiovascular diseases
Gut bacteria
Immune cells
Public health
Fig. 1.
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