IMR Press / JIN / Volume 18 / Issue 2 / DOI: 10.31083/j.jin.2019.02.159
Open Access Original Research
Electrophysiological modulation and cognitive-verbal enhancement by multi-session Broca's stimulation: a quantitative EEG transcranial direct current stimulation based investigation
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1 Department of Foreign Languages and Linguistics, Shiraz University, Shiraz, 7194685115, Iran
2 DANA Brain Health Institute, Iranian Neuroscience Society, Fars Chapter, Shiraz, 7183611557, Iran
3 Neuroscience Laboratory-NSL (Brain, Cognition and Behavior), Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, 7184737798, Iran
4 Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, 7184737798, Iran
5 Academy of Health, Senses Cultural Foundation, Sacramento, CA, 95826, USA
*Correspondence: torabinami@sums.ac.ir (Mohammad Nami)
J. Integr. Neurosci. 2019, 18(2), 107–115; https://doi.org/10.31083/j.jin.2019.02.159
Submitted: 27 April 2019 | Accepted: 26 June 2019 | Published: 30 June 2019
Copyright: © 2019 Kheradmand Saadi et al. Published by IMR press.
This is an open access article under the CC BY-NC 4.0 license (https://creativecommons.org/licenses/by-nc/4.0/)
Abstract

To evaluate transcranial direct current stimulation-induced changes in resting state quantitative EEG and cognitive-verbal performance of second language learners, 16 healthy individuals were randomly recruited to sham and real transcranial direct current stimulation groups receiving eight sessions of second language instruction accompanied by a 2 mA transcranial direct current stimulation over Broca's area with the cathode placed over the left arm. Quantitative EEG was recorded during the resting state after the stimulation session and second language instruction. Reduced theta activity at Fp1, F7, F3, and T5 caused by the stimulus current was reported. Multisession stimulation resulted in a significant increase in current density for beta power (25 Hz) in the language network. Cognitive-verbal pre-post stimulation performances suggest that anodal vs. sham transcranial direct current stimulation significantly improved the subjects test score on digit span, a cognitive-verbal ability. It is concluded that transcranial direct current stimulation of Broca's area increase cognitive-verbal performance by modulating brain electrical activity in language-related regions.

Keywords
qEEG
transcranial direct current stimulation
Broca's area
cognitive-verbal function
current density
Figures
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