IMR Press / FBS / Volume 9 / Issue 1 / DOI: 10.2741/S473

Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.


Cancer treatment with nano-diamonds

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1 Amity Institute for Herbal Research and Studies, Amity University UP, Sector-125, Noida-201313, India
2 Department of Zoology, R.G.P.G. College, Chippi Tank, Meerut-250001, India

*Author to whom correspondence should be addressed.

Front. Biosci. (Schol Ed) 2017, 9(1), 62–70;
Published: 1 January 2017

Diamond nano-particles find new and far-reaching applications in modern biomedical science and biotechnologies. Due to its excellent biocompatibility, nano-diamonds serve as versatile platforms that can be embedded within polymer-based microfilm devices. Nano-diamonds are complexed with a chemotherapeutic that enables sustained/slow release of the drug for a minimum of one month, with a significant amount of drug in reserve. This opens up the potential for highly localized drug release as a complementary and potent form of treatment with systemic injection towards the reduction of continuous dosing, and as such, attenuation of the often powerful side effects of chemotherapy. Nano-diamonds are quite economical, enabling the broad impact of these devices towards a spectrum of physiological disorders e.g. serving as a local chemotherapeutic patch, or as a pericardial device to suppress inflammation after open heart surgery. Nano-diamond patch could be used to treat a localized region where residual cancer cells might remain after a tumor is removed. Nano-diamonds can be used to explore a broad range of therapeutic classes, including additional small molecules, proteins, therapeutic antibodies, RNAi.

Drug delivery
Carbon nanoparticles
Brain tumors
Breast cancer
Chemo resistance
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