Department of Molecular Biology, University of Gdansk, Gdansk, PolandInterests: Genetic and neurodegenerative diseases; lysosomal storage diseases; molecular mechanisms of inherited metabolic diseases; regulation of gene expression; DNA replication controlSpecial Issues and Topics in IMR Press journals
Dear Colleagues,
Mucopolysaccharidoses (MPS) refers to a group of lysosomal storage disorders. These are severe, monogenic, inherited metabolic diseases caused by mutations in genes coding for enzymes involved in the degradation of glycosaminoglycans (GAGs). Lysosomal storage of GAGs is the primary biochemical defect. However, recent studies suggest the underlying pathological mechanisms of MPS are much more complicated. Secondary and tertiary effects can significantly modulate the disease course and may be as important as the primary cause. Furthermore, the development of effective therapies require detailed knowledge of the disease mechanism(s). This special issue will publish high quality articles on the pathological mechanisms of MPS. Both original research papers and review articles are welcome, provided they make a significant contribution to our understanding of the mechanisms of these diseases. Papers describing the development of potential new therapies for MPS are also welcome.
Grzegorz Węgrzyn
Guest Editor
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.