IMR Press / FBL / Volume 2 / Issue 1 / DOI: 10.2741/A160

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Functional bioinformatics: the cellular response database
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1 Department of Information Systems, University of Maryland Baltimore County, Baltimore, Maryland, USA
2 The Department of Pathology and Laboratory Service Baltimore VA Medical Center, Baltimore, Maryland, USA
3 Department of Pathology, University of Maryland at Baltimore School of Medicine, Baltimore, Maryland, USA
Front. Biosci. (Landmark Ed) 1997, 2(1), 31–36;
Published: 1 November 1997

Biological Scientists function in an increasingly data rich environment. The emerging field of bioinformatics is attempting to insure that this flow of information can be structured to support the generation of significant biological hypothesis and ultimately new knowledge. To date, most of the current databases have focused on protein and nucleic acid sequence information as the principle type of data stored for further interpretation. In this paper, we describe the Cellular Response Database. This database stores functional information regarding the changes of cellular gene expression associated with various stimuli, and supports queries linking cell types, expressed genes, and inducers. The database is designed to support information-intensive queries to aid in the determination of biological function, and is flexible enough to allow the storage of a broad range of experimental data such as cytotoxicity data, immunoassays of target gene protein expression, and others.

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