IMR Press / FBL / Volume 18 / Issue 4 / DOI: 10.2741/4183

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Effects and mechanisms of mechanical stress on secondary fracture healing

Show Less
1 Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, No.600 Yishan Road, Shanghai 200233, China
Academic Editor:Fei He
Front. Biosci. (Landmark Ed) 2013, 18(4), 1344–1348;
Published: 1 June 2013
(This article belongs to the Special Issue Cellular immunology and stem cell biology)

Fracture healing is an extremely complex biological reconstruction process, affected by age, hormones, blood supply, degree of injury, mechanical load and many other factors, among which, mechanical stimuli is one of the most important. Bone tissue has a good adaptability to mechanical stress, as biomechanical studies have shown that the local mechanical environment of the fracture site plays a regulatory role in the process of fracture healing (1,2). The present article reviews the mechanical mechanisms and effects of mechanical stress on fracture healing.

Mechanical Stress
Secondary Fracture Healing
Back to top