Genetically-modified animals as research models in development and disease
Submission Deadline: 31 Dec 2012
Guest Editor
Keywords
- Genes and Genetics
- Molecular Biology
Published Papers (37)
Regulation of cell proliferation and differentiation in the kidney
Front. Biosci. (Landmark Ed) 2009, 14(13), 4978–4991; https://doi.org/10.2741/3582
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Mouse models to study angiogenesis in the context of cardiovascular diseases
Front. Biosci. (Landmark Ed) 2009, 14(9), 3310–3325; https://doi.org/10.2741/3454
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
The use of genetically engineered model systems for research on human aging
Front. Biosci. (Landmark Ed) 2008, 13(18), 7022–7031; https://doi.org/10.2741/3207
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Control of atherosclerotic plaque vulnerability: insights from transgenic mice
Front. Biosci. (Landmark Ed) 2008, 13(16), 6289–6313; https://doi.org/10.2741/3155
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Knock-out mouse models of proprotein convertases: unique functions or redundancy?
Front. Biosci. (Landmark Ed) 2008, 13(13), 4960–4971; https://doi.org/10.2741/3055
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers
Front. Biosci. (Landmark Ed) 2008, 13(8), 2797–2805; https://doi.org/10.2741/2886
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice
Front. Biosci. (Landmark Ed) 2007, 12(12), 4722–4730; https://doi.org/10.2741/2421
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Function and regulation of the complement system in cardiovascular diseases
Front. Biosci. (Landmark Ed) 2007, 12(12), 4696–4708; https://doi.org/10.2741/2419
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Of mice without pockets: mouse models to study the function of Rb family proteins
Front. Biosci. (Landmark Ed) 2007, 12(7), 4483–4496; https://doi.org/10.2741/2403
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Protein isoprenylation in biology and disease: general overview and perspectives from studies with genetically engineered animals
Front. Biosci. (Landmark Ed) 2007, 12(7), 4456–4472; https://doi.org/10.2741/2401
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Murine models to investigate the influence of diabetic metabolism on the development of atherosclerosis and restenosis
Front. Biosci. (Landmark Ed) 2007, 12(7), 4439–4455; https://doi.org/10.2741/2400
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Potential contribution of bone marrow-derived precursors to vascular repair and lesion formation: lessons from animal models of vascular diseases
Front. Biosci. (Landmark Ed) 2007, 12(11), 4157–4167; https://doi.org/10.2741/2377
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Genetically-engineered animals as research models for atherosclerosis: their use for the characterization of PPAR agonists in the treatment of cardiometabolic disorders
Front. Biosci. (Landmark Ed) 2007, 12(11), 4132–4156; https://doi.org/10.2741/2376
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Retromer and sorting nexins in development
Front. Biosci. (Landmark Ed) 2007, 12(10), 3825–3851; https://doi.org/10.2741/2355
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
An insight into the pathophysiology of thrombosis in antiphospholipid syndrome
Front. Biosci. (Landmark Ed) 2007, 12(8), 3093–3103; https://doi.org/10.2741/2297
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
The GCK II and III subfamilies of the STE20 group kinases
Front. Biosci. (Landmark Ed) 2007, 12(3), 850–859; https://doi.org/10.2741/2107
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
The risk for cardiovascular disease in women: from estrogens to selective estrogen receptor modulators
Front. Biosci. (Landmark Ed) 2007, 12(1), 49–68; https://doi.org/10.2741/2048
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Age-related cardiac deterioration: insights from Drosophila
Front. Biosci. (Landmark Ed) 2007, 12(1), 39–48; https://doi.org/10.2741/2047
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Yeast as a model system to study glucose-mediated signalling and response
Front. Biosci. (Landmark Ed) 2007, 12(6), 2358–2371; https://doi.org/10.2741/2238
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice
Front. Biosci. (Landmark Ed) 2007, 12(6), 2291–2298; https://doi.org/10.2741/2231
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Genetically engineered mice as a model for studying cardiac arrhythmias
Front. Biosci. (Landmark Ed) 2007, 12(1), 22–38; https://doi.org/10.2741/2046
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Type-2 diabetic Leprdb/db mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia
Type-2 diabetic Leprdb/db mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia
Front. Biosci. (Landmark Ed) 2007, 12(6), 2003–2012; https://doi.org/10.2741/2205
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Animal models for the study of liver regeneration: role of nitric oxide and prostaglandins
Front. Biosci. (Landmark Ed) 2007, 12(1), 13–21; https://doi.org/10.2741/2045
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Cell fusion: biological perspectives and potential for regenerative medicine
Front. Biosci. (Landmark Ed) 2007, 12(1), 1–12; https://doi.org/10.2741/2044
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Cyclooxygenase 2: understanding the pathophysiological role through genetically altered mouse models
Front. Biosci. (Landmark Ed) 2006, 11(3), 2876–2888; https://doi.org/10.2741/2016
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Atheroma development in apolipoprotein E-null mice is not affected by partial inactivation of PTEN
Front. Biosci. (Landmark Ed) 2006, 11(3), 2739–2745; https://doi.org/10.2741/2003
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice
Front. Biosci. (Landmark Ed) 2006, 11(2), 1328–1348; https://doi.org/10.2741/1887
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models
Front. Biosci. (Landmark Ed) 2006, 11(1), 955–967; https://doi.org/10.2741/1852
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
New animal models to study the role of tyrosinase in normal retinal development
Front. Biosci. (Landmark Ed) 2006, 11(1), 743–752; https://doi.org/10.2741/1832
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Endometriosis: harmful survival of an ectopic tissue
Front. Biosci. (Landmark Ed) 2006, 11(1), 595–619; https://doi.org/10.2741/1821
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Controlled gene activation and inactivation in the mouse
Front. Biosci. (Landmark Ed) 2006, 11(1), 313–327; https://doi.org/10.2741/1799
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Cyclins and CDKS in development and cancer: lessons from genetically modified mice
Front. Biosci. (Landmark Ed) 2006, 11(1), 1164–1188; https://doi.org/10.2741/1871
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Mammalian genome targeting using site-specific recombinases
Front. Biosci. (Landmark Ed) 2006, 11(1), 1108–1136; https://doi.org/10.2741/1867
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Stem cells for cardiac repair: state of the art
Front. Biosci. (Landmark Ed) 2005, 10(3), 3143–3150; https://doi.org/10.2741/1771
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1)
Front. Biosci. (Landmark Ed) 2005, 10(3), 2978–2985; https://doi.org/10.2741/1754
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Vitamin D and cancer: an update of in vitro and in vivo data
Vitamin D and cancer: an update of in vitro and in vivo data
Front. Biosci. (Landmark Ed) 2005, 10(3), 2723–2749; https://doi.org/10.2741/1731
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)
Transcriptional profiling of early onset diet-induced atherosclerosis in apolipoprotein E-deficient mice
Front. Biosci. (Landmark Ed) 2005, 10(2), 1932–1945; https://doi.org/10.2741/1669
(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)