IMR Press / RCM / Special Issues / 1617155252942

The treatment of mitral regurgitation in the 21st Century

Submission deadline: 01 November 2021
Special Issue Editors
  • Francesco Nappi, MD
    Centre Cardiologique du Nord, Department of Cardiac Surgery, Saint-Denis, France
    Interests: valve surgery; coronary surgery; aortic surgery; cardiac biomechanics; tissue biomodeling tissue engineering and regenerative medicine
  • Cristiano Spadaccio, MD, PhD
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom
  • Christos Mihos, MD
    Echocardiography Laboratory, Columbia University Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL
    Interests: Heart Valve; Echocardiography
  • Massimo Chello
    Cardiovascular surgery, Università Campus Bio-Medico di Roma, 00128, Rome, Italy
    Interests: Valve surgery; Coronary surgery; Aortic surgery; Tissue engineering and regenerative medicine
Special Issue Information

Dear Colleagues,


In the recent year mitral valve treatment underwent a significant evolution. The emerging technology of transcatheter mitral valve replacement (TMVR) has deeply influenced the scenario of the surgical management of mitral regurgitation. At the same time, new concepts in mitral disease based on the relation between of the left ventricle, subvalvular apparatus and mitral valve as a functional unit, have been proposed.
Established and more modern surgical techniques have been further developed, with a renovated interest to surgery of the subvalvular apparatus. Progresses have been made in the field of minimally invasive and robotic surgery, opening the way to new paradigms in mitral valve surgery.
In this special issue, the most recent developments and trends in mitral surgery will be discussed. Original articles, reviews, commentaries, case reports and “how-to-do it” contributions will be taken into consideration for this issue. The aim is to provide a realistic and updated status of mitral regurgitation treatment based on the most recent evidence in this field. 


Dr. Francesco Nappi, Dr. Spadaccio Cristiano, Dr. Christos Mihos and Prof. Massimo Chello

Guest Editors

Mitral valve surgery
Transcatheter mitral valve replacement
Minimally invasive surgery
Robotic surgery
Manuscript Submission Information

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Published Paper (4 Papers)
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