IMR Press / RCM / Volume 24 / Issue 11 / DOI: 10.31083/j.rcm2411320
Open Access Review
Research Progress of Low-Voltage Areas Associated with Atrial Fibrillation
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1 Department of Cardiology, Luoyang Central Hospital Affiliated to Zhengzhou University, 471000 Luoyang, Henan, China
2 Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, 300091 Tianjin, China
3 The Department of Cardiology, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden
*Correspondence: (Yunfei Gu); (Tong Liu)
Rev. Cardiovasc. Med. 2023, 24(11), 320;
Submitted: 23 March 2023 | Revised: 5 May 2023 | Accepted: 24 May 2023 | Published: 17 November 2023
(This article belongs to the Section Clinical Electrophysiology)
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Atrial fibrosis is an independent predictor of the recurrence of atrial fibrillation (AF) after catheter ablation. Low-voltage areas (LVA) measured during catheter ablation for AF are a commonly used surrogate for the presence of atrial fibrosis. LVA are associated with clinical outcomes and comorbidities and have links to triggering sites for AF. Several trials have shown promising data of targeting ablation in LVA, however the results have been mixed. This article will review the role of LVA in the prediction of adverse events in AF patients, including stroke, how to predict the presence of LVA, and the impact of LVA ablation on the recurrence of AF.

atrial fibrillation
low-voltage areas
catheter ablation
atrial fibrosis
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222102310076/Henan Province Key R&D and Promotion Project
LHGJ20220933/Henan Provincial Science and Technology Research Project
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