IMR Press / FBS / Volume 2 / Issue 2 / DOI: 10.2741/s73

Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Clinical and biological markers in gastric cancer: update and perspectives

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1 University of Catania, Department of Surgery, General and Breast Surgery Unit, University Hospital of Catania, Italy
2 Department of Medical Oncology, National Cancer Institute – IRCCS, Aviano (PN), Italy
3 University of Catania, Department of Surgery, Transplantation and Advanced Technologies, Vascular Surgery and Organ Transplant Unit, University Hospital of Catania, Italy
4 University of Catania, Department of Internal Medicine, “Garibaldi-Nesima” Hospital, University of Catania, Catania, Italy
5 University of Catania, Research Fellow in Surgical PathologyCatania, Italy
6 University of Maryland, Division of Laparoscopic and Bariatric Surgery, Baltimore, MD, USA
7 Department of Anaesthesia and Intensive Care, Catania University Hospital, Catania, Italy
Front. Biosci. (Schol Ed) 2010, 2(2), 403–412; https://doi.org/10.2741/s73
Published: 1 January 2010
Abstract

Gastric cancer is the second cause of death from cancer worldwide and the only chance to reach better outcomes lays on an early diagnosis. The need for non-invasive, low-cost tests is invoked also in countries in which imaging and endoscopic screening have already showed the ability to improve early diagnosis and overall survival. Genomic medicine could allow a better understanding of regulatory pathways driving the development and growth of gastric cancer and the characterization of specific molecular targets actually stimulate new drug developments. The knowledge of the role of Helicobacter pylori (HP) in gastric tumor pathogenesis has put new insides in the understanding of this peculiar disease and enriched the field of gastric biomarkers.

Keywords
Gastric cancer
Metastasis
Markers
Screening
Follow Up
Review
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