- Academic Editor
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Background: Significant hemodynamic, hormonal, and metabolic impairment
of a brain-dead organ donor is often associated with the deterioration of graft
viability. This study aimed to compare the effect of heparin therapy as a
therapeutic dose after brain death confirmation on early graft survival in kidney
and liver recipients. Method and Materials: The deceased donors were
sorted into two groups based on their D-dimer level. After confirming brain
death, one group was given a heparin injection (case group), while the other
group did not receive any heparin (control group). A total of 71 brain death
donors and matched kidney and liver transplants were included in the case group.
A total of 43 brain death donors and matched kidney and liver transplants were
included in the control group. A total of 5000 units of heparin were administered
every 6 hours to the deceased donor case group. Results: The mean age of
the case and control groups were 36.27