IMR Press / FBS / Volume 14 / Issue 3 / DOI: 10.31083/j.fbs1403020
Open Access Original Research
Safety and Appropriateness in the Management of the Treatment Pathway of Pregnant Women with Gestational Diabetes
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1 Pharmacy and Clinical Pharmacology Unit, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo", 34137 Trieste, Italy
2 Diabetes Center, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, Italy
3 Clinical Epidemiology and Public Health Research Unit, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo", 34137 Trieste, Italy
4 Diabetes Center, Azienda sanitaria universitaria Giuliano Isontina (ASU GI), 34074 Monfalcone (GO), Italy
5 Pharmacy Unit, Azienda sanitaria universitaria Friuli Centrale (ASU FC), 33100 Udine, Italy
6 Diabetes Center, Azienda sanitaria universitaria Friuli Centrale (ASU FC), 33100 Udine, Italy
7 Direzione centrale salute, politiche sociali e disabilità - Servizio pianificazione, controllo, economia sanitaria e assistenza farmaceutica, Regione Autonoma Friuli Venezia-Giulia, 34121 Trieste, Italy
*Correspondence: (Giulia Fornasier)
These authors contributed equally.
Academic Editor: Yoshinori Marunaka
Front. Biosci. (Schol Ed) 2022, 14(3), 20;
Submitted: 17 February 2022 | Revised: 12 April 2022 | Accepted: 20 April 2022 | Published: 21 July 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Gestational diabetes (GDM) is quite common during pregnancy, and its prevalence is rising because of the increased overweight and obesity rates. In patients with GDM, proper glycemic control, adherence to a suitable diet and antidiabetic treatments can reduce the likelihood of maternal-neonatal complications. For this reason, this study aims to assess the therapy adherence of pregnant women with GDM. Treatment adherence was assessed by both glucometer and diabetologist’s analysis reported in the electronic medical record. Cohen’s Kappa was used to assess the agreement between the two classifications. Moreover, a multivariate logistic regression analysis was performed to identify potential risk factors for non-adherence to treatment. Overall, 287 patients were enrolled, and 271 were available for follow-up. Low concordance between the glucometer and the diabetologist’s analysis was found, mainly due to the complexity of patients with GDM. Indeed, 46% of patients were classified as not adherent due to glucometer results and 42% based on medical assessment. This study highlights the importance of monitoring patients with gestational diabetes to assess and increase adherence to therapy properly.

gestational diabetes
glucometer analysis
diabetologist analysis
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