IMR Press / FBL / Special Issues / endodontics_adhesive_dentistry

Innovations in Endodontics and Adhesive Dentistry: From Root Canal Treatments to Adhesive Rehabilitation

Submission deadline: 20 December 2023
Special Issue Editors
  • Alessio Zanza
    Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy
    Interests: endodontics; adhesive dentistry; nickel-titanium rotary instruments; adhesive; composite; sealers; irrigation; mechanical stress; restorative dentistry; dental imaging; diagnosis
  • Luca Testarelli, PhD
    Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy
    Interests: endodontics; restorative dentistry; implantology; oral surgery; dental imaging
    Special Issues and Topics in IMR Press journals
  • Rodolfo Reda, PhD
    Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy
    Interests: endodontics; restorative dentistry; implantology; prosthodontics; dental imaging
Special Issue Information

Dear Colleagues,

In the last years, the endodontic and adhesive dentistry fields have been thoroughly changed thanks to great innovations proposed both in terms of materials and techniques. The advances in technology have led to the introduction of performant materials, especially regarding the chemo-mechanical disinfection and obturation of endodontic systems. As a matter of fact, the development of innovative designs of nickel-titanium rotary instruments in combination with heat treatments has guaranteed levels of predictability of root canal shaping never seen before. Despite this, the success of orthograde endodontics does not depend exclusively on mechanical root canal debridement but is based mainly on its chemical disinfection. The introduction of irrigants activators has led to an increase in bacteria eradication and smear layer removal, guaranteeing a higher percentage of long-term success. Regarding this, researchers have proposed alternative irrigants to the traditional sodium hypochlorite and EDTA, introducing the concept of continuous chelation. The actual potential of those innovations should be addressed more intensively, providing scientific data to support those concepts. Moreover, the its relationship with the healing process and inflammation pathways in terms of cytotoxicity, biological effects and bacterial eradication are still unclear.

Nevertheless, the long-term outcome is not influenced only by the chemo-mechanical disinfection of the endodontic system but also by the obturation quality of both coronal and apical zones, preventing the recolonization or replication of persisting bacteria. Also regarding this, the innovations have allowed clinicians to count on efficient materials with interesting biological and physio-chemical properties such as hydraulic sealers. Despite this, current data are still scarce and further research is needed, especially regarding in vivo studies with long-term follow-ups.

Moreover, recent studies have investigated the effects of those innovative materials on the human periodontal ligament and particularly on its stem cell. Despite this, the data are still scarce and further research should be conducted, particularly on the consequences of hydraulic sealers extrusion and its effect on the inflammation pathway and healing process.

In conclusion, this special issue will include all articles regarding the whole endodontic process, particularly focusing on all areas of cellular and molecular biology related to endodontic and adhesive restorative procedures.

Dr.  Alessio Zanza, Prof. Luca Testarelli and Dr. Rodolfo Reda
Guest Editors

adhesive dentistry
nickel-titanium rotary instruments
mechanical stress
restorative dentistry
dental imaging
molecular biology
stem cell
inflammation pathways
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

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