IMR Press / FBL / Volume 24 / Issue 4 / DOI: 10.2741/4750

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Long noncoding RNA and its role in virus infection and pathogenesis
Show Less
1 College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua, Zhejiang, China
2 Key Laboratory of Wildlife Biotechnology and Conservation and Utilization of Zhejiang Province, Zhejiang Normal University, Jinhua, Zhejiang, China
*Correspondence: tjzhao@zjnu.cn (Tiejun Zhao)
Front. Biosci. (Landmark Ed) 2019, 24(4), 777–789; https://doi.org/10.2741/4750
Published: 1 March 2019
Abstract

Long noncoding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that regulate gene expression at the transcriptional and post-transcriptional levels. Emerging evidence showed that lncRNAs play important roles in a wide range of biological processes, including cell proliferation, apoptosis, and tumorigenesis. The infection of virus generally can regulate the expression of the cellular lncRNA expression. The lncRNAs which encoded by virus can also modulate the expression of the hosts’ gene which is critical for virus infection. Here, we summarized the recent progress on long noncoding RNA and its relationship with virus, especially the function of long noncoding RNA on virus-induced oncogenesis. Studies on lncRNAs and their relationship with viruses may give new insights into virus-host interactions and therapy of related diseases.

Keywords
Long noncoding
RNA
Virus
Review
Figures
Figure 1
Share
Back to top