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Article
Emergence of life: from functional RNA selection to natural selection and beyond
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1
Division of Life Science and Applied Genomics Center, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, People's Republic of China
Front. Biosci. (Landmark Ed) 2014, 19(7), 1117–1150;
https://doi.org/10.2741/4271
Published: 1 June 2014
Abstract
This study tracks the rise, evolution and post-evolution of the genetic information system through emergence of life. The major stages traversed include prebiotic synthesis, functional RNA selection by metabolite, RNA World, peptidated RNA world, co-evolution of genetic code and amino acid biosynthesis, last universal common ancestor, Darwinian evolution and synthetic life.
Keywords
Metabolic Expansion Law
RNA World
Peptidated RNA World
Coevolution Theory
Last Universal Common Ancestor
synthetic life