IMR Press / FBL / Volume 16 / Issue 5 / DOI: 10.2741/3808

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Role of cereal type and processing in whole grain in vivo protection from oxidative stress
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1 Department of Food Sciences, University of Bologna, Viale Fanin 44, 40127 Bologna, BO, Italy
2 Department of Biochemistry, G. Moruzzi, University of Bologna, Via Irnerio, 48 - 40126 Bologna (BO), Italy

Academic Editor: Fabio Galvano

Front. Biosci. (Landmark Ed) 2011, 16(5), 1609–1618;
Published: 1 January 2011
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)

The reduced risk of chronic diseases related to whole grain consumption is in part attributed to their high antioxidant content. Many studies have been performed on the in vitro antioxidant capacity of cereals, but in vivo studies are necessary. We have evaluated and compared the effect of whole grain durum wheat bread and whole grain Kamut khorasan bread on the oxidative status in rats. Two different bread-making processes were used for whole grain Kamut khorasan, sourdough and baker's yeast. After 7 weeks on the experimental diets rats were divided into two subgroups, one receiving an oxidative stress by doxorubicin injection. Our results evidenced both wheat durum and Kamut khorasan as good sources of antioxidants, and a lower oxidative state in rats fed the cereal-based diets. Furthermore, Kamut khorasan bread fed animals had a better response to stress than wheat durum fed, especially when a sourdough bread was supplied. Although further studies are needed, data herein reported suggest whole grains, particularly whole ancient grains, as a safe and convenient way of increasing antioxidant protection.

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