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Effect of a low glycemic diet in patients with polycystic ovary syndrome and anovulation - a randomized controlled trial
L. H. Sordia-Hernández Sordia-Hernández1,*, P. Ancer Rodríguez Rodríguez2, D. Saldivar Rodriguez1, S. Trejo Guzmán Guzmán2, E. S. Servín Zenteno1, G. Guerrero González González1, R. Ibarra Patiño Patiño1
1 Centro Universitario de Medicina Reproductiva, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey
2 Departamento de Nutrición, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey (Mexico)
Clin. Exp. Obstet. Gynecol. 2016, 43(4), 555–559; https://doi.org/10.12891/ceog3037.2016
Published: 10 August 2016
Objective: To determine whether a low glycemic index diet is better than a normal glycemic index diet in producing ovulatory cycles in women with polycystic ovary syndrome (PCOS) and anovulation. Materials and Methods: A randomized controlled clinical trial involving 37 women with PCOS and anovulation. The authors randomly assigned low glycemic index diets (n = 19) and normal glycemic index (n = 18) diets, and analyzed the number of ovulatory cycles for three months. Results: In patients who consumed a low glycemic index diet, 24.6% (14/57) of the cycles were ovulatory. In those who consumed a normal glycemic index diet, only 7.4% (4/54) of the cycles were ovulatory (p = 0.014). Conclusions: The difference observed in the number of ovulatory cycles could be related to a decrease in the serum levels of circulating androgens, secondary to an improvement in insulin resistance.
Polycystic ovary syndrome