IMR Press / JIN / Volume 20 / Issue 2 / DOI: 10.31083/j.jin2002048
Open Access Case Report
Multiple myeloma complicated by skull plasmacytoma discovered after head injury
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1 Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100010 Beijing, China
*Correspondence: (Ming Feng)
These authors contributed equally.
J. Integr. Neurosci. 2021, 20(2), 459–462;
Submitted: 25 February 2021 | Revised: 5 March 2021 | Accepted: 28 April 2021 | Published: 30 June 2021
Copyright: © 2021 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license (

Plasmacytoma is a malignant tumor originating from the plasma cells of the bone marrow. Those discovered after a head injury is rare. We report a case of a 48-year-old female who complained of scalp mass without other symptoms after head injury. Meningioma was considered preoperatively based on imaging findings, and surgical resection was performed. Postoperatively, multiple myeloma complicated by skull plasmacytoma was diagnosed by histopathology and systematic examinations in succession. When evaluating a head mass that appeared after a head injury, plasmacytoma should be considered at times. Osteolytic changes and biconvex form on imaging are beneficial to differentiation.

Head injury
Skull plasmacytoma
Multiple myeloma
Fig. 1.
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