Volume 27, Issue 1 (February 2026)

Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery

Open Access 28 Feb 2026Original Article

Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery

Lijun Chu, Xiaoju Jia, Ping Gao, Xia Sun, Jian Zhang, Yu Ding, Shiwang Chen, Fuyou Bi, Chuhao Zhang, Dazhi Li, Yong Zhang

Alpha Psychiatry 2026, 27(1), 47409; https://doi.org/10.31083/AP47409

Abstract

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596

Prediction of Smartphone Addiction Among Korean Adolescents Based on Physical Activity and Mental Health: A Machine Learning Analysis Using LASSO and SHAP From the Korea Youth Risk Behavior Survey

Open Access 26 Feb 2026Original Article

Prediction of Smartphone Addiction Among Korean Adolescents Based on Physical Activity and Mental Health: A Machine Learning Analysis Using LASSO and SHAP From the Korea Youth Risk Behavior Survey

Kihyuk Lee, Wooin Seo, Se Young Jung

Alpha Psychiatry 2026, 27(1), 46201; https://doi.org/10.31083/AP46201

Abstract

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312

Integrated Interventions for Executive Function Deficits in Children with Autism Spectrum Disorder: From Cognitive Training to Neuroregulation

Open Access 26 Feb 2026Review

Integrated Interventions for Executive Function Deficits in Children with Autism Spectrum Disorder: From Cognitive Training to Neuroregulation

Liuyan Zhu, Dan Yao

Alpha Psychiatry 2026, 27(1), 40062; https://doi.org/10.31083/AP40062

Abstract

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359

Alexithymia, Resilience, and Depression in Functional Impairment Among Adolescents With Eating Disorders: A Case-Control Study

Open Access 26 Feb 2026Original Article

Alexithymia, Resilience, and Depression in Functional Impairment Among Adolescents With Eating Disorders: A Case-Control Study

Yavuz Meral, Saliha Açıkgöz, Alperen Bıkmazer, Büşra Arslan, Oğuzhan Koyuncu, Melike Ayşegül Kara Karaman, Vahdet Görmez

Alpha Psychiatry 2026, 27(1), 45458; https://doi.org/10.31083/AP45458

Abstract

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421

UPLC-MS/MS Analytical Method for the Simultaneous Quantification of Diazepam, Nordazepam, and Oxazepam in Patients With Alcohol Dependence

Open Access 26 Feb 2026Original Article

UPLC-MS/MS Analytical Method for the Simultaneous Quantification of Diazepam, Nordazepam, and Oxazepam in Patients With Alcohol Dependence

Xiao-Lin Li, Wan-Ting Huang, Xiao-Jia Ni, Hao-Yang Lu, Shan-Qing Huang, Yu-Qing Li, Huan-Shan Xie, Yu-Guan Wen, Zhan-Zhang Wang, De-Wei Shang

Alpha Psychiatry 2026, 27(1), 38973; https://doi.org/10.31083/AP38973

Abstract

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420

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Open Access 25 Feb 2026Systematic Review

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Yuval Singer, Assif Yitzhaky, Libi Hertzberg

Alpha Psychiatry 2026, 27(1), 43531; https://doi.org/10.31083/AP43531

Abstract

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260

Group Sparse Representation Enhances Brain Network Classification of Major Depressive Disorder in Two Chinese Cohorts

Open Access 25 Feb 2026Original Article

Group Sparse Representation Enhances Brain Network Classification of Major Depressive Disorder in Two Chinese Cohorts

Defu Zhang, Cancan Lin, Aoxue Zhang, Xubo Wang, Wenjie Xia, Yue Wang, Yuxin Du, the DIRECT Consortium, Hao Yu, Shanling Ji

Alpha Psychiatry 2026, 27(1), 40685; https://doi.org/10.31083/AP40685

Abstract

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308

Sex Differences in Social Media Addiction: The Mediating Effects of Social Media Use Motives

Open Access 25 Feb 2026Original Article

Sex Differences in Social Media Addiction: The Mediating Effects of Social Media Use Motives

Young-Jin Lim

Alpha Psychiatry 2026, 27(1), 46105; https://doi.org/10.31083/AP46105

Abstract

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278

Serum Claudin-5 and Peripheral Inflammation in Major Depressive Disorder: A Case-Control Study with Focus on Suicidal Ideation

Open Access 25 Feb 2026Original Article

Serum Claudin-5 and Peripheral Inflammation in Major Depressive Disorder: A Case-Control Study with Focus on Suicidal Ideation

Nurbanu Keskin, Mahmut Selçuk, Ercan Saruhan

Alpha Psychiatry 2026, 27(1), 46843; https://doi.org/10.31083/AP46843

Abstract

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197

Neurocognitive Processing of Facial Emotion Recognition in Individuals With Depression and Suicidal Ideation: An Eye-Tracking and EEG Study

Open Access 25 Feb 2026Original Article

Neurocognitive Processing of Facial Emotion Recognition in Individuals With Depression and Suicidal Ideation: An Eye-Tracking and EEG Study

Qianlan Yin, Huijing Xu, Ying Zhu, Meng Liang, Qian Jiang, Bin Zhao, Taosheng Liu

Alpha Psychiatry 2026, 27(1), 44992; https://doi.org/10.31083/AP44992

(This article belongs to the Special Issue Twenty-five Years at the Alpha Psychiatry Progresses on Psychiatry)

Abstract

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280

Relationship Between Negative Cognition and Poor Quality of Life and Anxiety in Adolescents: A Meta-Analysis

Open Access 25 Feb 2026Systematic Review

Relationship Between Negative Cognition and Poor Quality of Life and Anxiety in Adolescents: A Meta-Analysis

Şenay Kılınçel, Oğuzhan Kılınçel

Alpha Psychiatry 2026, 27(1), 46205; https://doi.org/10.31083/AP46205

Abstract

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230

Reducing Disparities and Improving Mental Health for Transgender Persons

Open Access 25 Feb 2026Expert Opinion

Reducing Disparities and Improving Mental Health for Transgender Persons

Osborne F.X. Almeida, Pedro Morgado

Alpha Psychiatry 2026, 27(1), 45278; https://doi.org/10.31083/AP45278

Abstract

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506

ERP Decoding Analysis of Visual Working Memory Processes in Schizophrenia

Open Access 25 Feb 2026Original Article

ERP Decoding Analysis of Visual Working Memory Processes in Schizophrenia

Zhongsi Wang, Chunlei Liu, Yuyan Jing, Zhenzhen Yao, Min Chen

Alpha Psychiatry 2026, 27(1), 42597; https://doi.org/10.31083/AP42597

Abstract

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149

Evaluation of Short Term and Long Term Subjective and Objective Cognitive Outcomes Following ECT for Depression in a Naturalistic Ambulatory Setting: A Cohort Study

Open Access 3 Feb 2026Original Article

Evaluation of Short Term and Long Term Subjective and Objective Cognitive Outcomes Following ECT for Depression in a Naturalistic Ambulatory Setting: A Cohort Study

Sarah A. Goegan, Gary M. Hasey, Jelena P. King, Bruno J. Losier, Peter J. Bieling, Margaret C. McKinnon, Heather E. McNeely

Alpha Psychiatry 2026, 27(1), 45286; https://doi.org/10.31083/AP45286

Abstract

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317

Interrelationships Between Self-Injury Addiction, Traumatic Experiences, and Rumination Among Adolescents With Non-Suicidal Self-Injury: A Network Analysis

Open Access 3 Feb 2026Original Article

Interrelationships Between Self-Injury Addiction, Traumatic Experiences, and Rumination Among Adolescents With Non-Suicidal Self-Injury: A Network Analysis

Shijian Wang, Lin Zhao, Doudou Zheng, Linghua Kong, Jingya Li, Ying Yang

Alpha Psychiatry 2026, 27(1), 44340; https://doi.org/10.31083/AP44340

Abstract

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368

Structural Alterations and Cognitive Impairment in Late-Onset Depression: A Reverse Correlation Analysis

Open Access 3 Feb 2026Original Article

Structural Alterations and Cognitive Impairment in Late-Onset Depression: A Reverse Correlation Analysis

Yujie Wu, Naikeng Mai

Alpha Psychiatry 2026, 27(1), 44585; https://doi.org/10.31083/AP44585

Abstract

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319

Rethinking Autism as an Affective-Empathy Disorder

Open Access 3 Feb 2026Editorial

Rethinking Autism as an Affective-Empathy Disorder

Sergio Machado, Flávia Paes, João Lucas Lima

Alpha Psychiatry 2026, 27(1), 45867; https://doi.org/10.31083/AP45867

(This article belongs to the Special Issue Twenty-five Years at the Alpha Psychiatry Progresses on Psychiatry)

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351

Clinical Factors and Serum Biomarkers Associated With Major Depressive Disorder in Adolescents With and Without Nonsuicidal Self-Injury: A Comparative Cross-Sectional Study

Open Access 2 Feb 2026Original Article

Clinical Factors and Serum Biomarkers Associated With Major Depressive Disorder in Adolescents With and Without Nonsuicidal Self-Injury: A Comparative Cross-Sectional Study

Shengjiao Zhao, Xiaodan Dong, Jiahui Lu, Yanyan Wu, Ping Fang, Yu Zhang, Yujian Mou, Haiyan Xie

Alpha Psychiatry 2026, 27(1), 44160; https://doi.org/10.31083/AP44160

Abstract

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233

Efficacy and Mechanisms Underlying MRI-guided High-definition Transcranial Direct Current Stimulation Combined With Computerized Cognitive Remediation Therapy for Improving Cognitive Impairments in Schizophrenia: Study Protocol for a Randomized Controlled Trial

Open Access 2 Feb 2026Study Protocols

Yange Wei, Shanyuan He, Peng Luo, Rongxun Liu, Hanshuo Su, Zengyuan Shen, Shuqi Feng, Yanran Wu, Guangjun Ji, Wei Zheng, Fei Wang, Chuansheng Wang

Alpha Psychiatry 2026, 27(1), 46768; https://doi.org/10.31083/AP46768

(This article belongs to the Special Issue Schizophrenia: From Mechanisms to Clinical Studies)

Abstract

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486

Is Happiness a Possible Outcome for People With Schizophrenia?

Open Access 2 Feb 2026Editorial

Is Happiness a Possible Outcome for People With Schizophrenia?

Ilaria Riboldi, Giuseppe Carrà

Alpha Psychiatry 2026, 27(1), 46244; https://doi.org/10.31083/AP46244

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243

Insights from Tracing the Evolution of Automated Digital Mental Health Interventions in China

Open Access 12 Jan 2026Editorial

Insights from Tracing the Evolution of Automated Digital Mental Health Interventions in China

Jin Han

Alpha Psychiatry 2026, 27(1), 49906; https://doi.org/10.31083/AP49906

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435

Cognitive Impairment and Non-Invasive Neuromodulation Interventions in Bipolar Disorder: A Narrative Review of Current Status and Future Directions

Open Access 12 Jan 2026Review

Cognitive Impairment and Non-Invasive Neuromodulation Interventions in Bipolar Disorder: A Narrative Review of Current Status and Future Directions

Guilan Sun, Tongjie Zhuang, Minmin Wang, Xiaomei Zhang

Alpha Psychiatry 2026, 27(1), 42381; https://doi.org/10.31083/AP42381

Abstract

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562

Comparison of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Conventional Facemask Ventilation During Electroconvulsive Therapy in Major Mental Disorders: A Preliminary Open-Label Randomized Controlled Trial

Open Access 8 Jan 2026Original Article

Can-Jin Deng, Sha Nie, Rong Zeng, Jian-Xin Mai, Xiong Huang, Shi-Chao Xu, Xin-Hu Yang, Qing-Bin Zeng, Xing-Bing Huang, Wei Zheng

Alpha Psychiatry 2026, 27(1), 39942; https://doi.org/10.31083/AP39942

Abstract

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437

Volume 27, Issue 1 (2026)

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Article

Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery

Open Access 28 Feb 2026Original Article

Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery

Lijun Chu, Xiaoju Jia, Ping Gao, Xia Sun, Jian Zhang, Yu Ding, Shiwang Chen, Fuyou Bi, Chuhao Zhang, Dazhi Li, Yong Zhang

Alpha Psychiatry 2026, 27(1), 47409; https://doi.org/10.31083/AP47409

Abstract

Download

596

Prediction of Smartphone Addiction Among Korean Adolescents Based on Physical Activity and Mental Health: A Machine Learning Analysis Using LASSO and SHAP From the Korea Youth Risk Behavior Survey

Open Access 26 Feb 2026Original Article

Prediction of Smartphone Addiction Among Korean Adolescents Based on Physical Activity and Mental Health: A Machine Learning Analysis Using LASSO and SHAP From the Korea Youth Risk Behavior Survey

Kihyuk Lee, Wooin Seo, Se Young Jung

Alpha Psychiatry 2026, 27(1), 46201; https://doi.org/10.31083/AP46201

Abstract

Download

312

Integrated Interventions for Executive Function Deficits in Children with Autism Spectrum Disorder: From Cognitive Training to Neuroregulation

Open Access 26 Feb 2026Review

Integrated Interventions for Executive Function Deficits in Children with Autism Spectrum Disorder: From Cognitive Training to Neuroregulation

Liuyan Zhu, Dan Yao

Alpha Psychiatry 2026, 27(1), 40062; https://doi.org/10.31083/AP40062

Abstract

Download

359

Alexithymia, Resilience, and Depression in Functional Impairment Among Adolescents With Eating Disorders: A Case-Control Study

Open Access 26 Feb 2026Original Article

Alexithymia, Resilience, and Depression in Functional Impairment Among Adolescents With Eating Disorders: A Case-Control Study

Yavuz Meral, Saliha Açıkgöz, Alperen Bıkmazer, Büşra Arslan, Oğuzhan Koyuncu, Melike Ayşegül Kara Karaman, Vahdet Görmez

Alpha Psychiatry 2026, 27(1), 45458; https://doi.org/10.31083/AP45458

Abstract

Download

421

UPLC-MS/MS Analytical Method for the Simultaneous Quantification of Diazepam, Nordazepam, and Oxazepam in Patients With Alcohol Dependence

Open Access 26 Feb 2026Original Article

UPLC-MS/MS Analytical Method for the Simultaneous Quantification of Diazepam, Nordazepam, and Oxazepam in Patients With Alcohol Dependence

Xiao-Lin Li, Wan-Ting Huang, Xiao-Jia Ni, Hao-Yang Lu, Shan-Qing Huang, Yu-Qing Li, Huan-Shan Xie, Yu-Guan Wen, Zhan-Zhang Wang, De-Wei Shang

Alpha Psychiatry 2026, 27(1), 38973; https://doi.org/10.31083/AP38973

Abstract

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420

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Open Access 25 Feb 2026Systematic Review

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Yuval Singer, Assif Yitzhaky, Libi Hertzberg

Alpha Psychiatry 2026, 27(1), 43531; https://doi.org/10.31083/AP43531

Abstract

Download

260

Group Sparse Representation Enhances Brain Network Classification of Major Depressive Disorder in Two Chinese Cohorts

Open Access 25 Feb 2026Original Article

Group Sparse Representation Enhances Brain Network Classification of Major Depressive Disorder in Two Chinese Cohorts

Defu Zhang, Cancan Lin, Aoxue Zhang, Xubo Wang, Wenjie Xia, Yue Wang, Yuxin Du, the DIRECT Consortium, Hao Yu, Shanling Ji

Alpha Psychiatry 2026, 27(1), 40685; https://doi.org/10.31083/AP40685

Abstract

Download

308

Sex Differences in Social Media Addiction: The Mediating Effects of Social Media Use Motives

Open Access 25 Feb 2026Original Article

Sex Differences in Social Media Addiction: The Mediating Effects of Social Media Use Motives

Young-Jin Lim

Alpha Psychiatry 2026, 27(1), 46105; https://doi.org/10.31083/AP46105

Abstract

Download

278

Serum Claudin-5 and Peripheral Inflammation in Major Depressive Disorder: A Case-Control Study with Focus on Suicidal Ideation

Open Access 25 Feb 2026Original Article

Serum Claudin-5 and Peripheral Inflammation in Major Depressive Disorder: A Case-Control Study with Focus on Suicidal Ideation

Nurbanu Keskin, Mahmut Selçuk, Ercan Saruhan

Alpha Psychiatry 2026, 27(1), 46843; https://doi.org/10.31083/AP46843

Abstract

Download

197

Neurocognitive Processing of Facial Emotion Recognition in Individuals With Depression and Suicidal Ideation: An Eye-Tracking and EEG Study

Open Access 25 Feb 2026Original Article

Neurocognitive Processing of Facial Emotion Recognition in Individuals With Depression and Suicidal Ideation: An Eye-Tracking and EEG Study

Qianlan Yin, Huijing Xu, Ying Zhu, Meng Liang, Qian Jiang, Bin Zhao, Taosheng Liu

Alpha Psychiatry 2026, 27(1), 44992; https://doi.org/10.31083/AP44992

(This article belongs to the Special Issue Twenty-five Years at the Alpha Psychiatry Progresses on Psychiatry)

Abstract

Download

280

Relationship Between Negative Cognition and Poor Quality of Life and Anxiety in Adolescents: A Meta-Analysis

Open Access 25 Feb 2026Systematic Review

Relationship Between Negative Cognition and Poor Quality of Life and Anxiety in Adolescents: A Meta-Analysis

Şenay Kılınçel, Oğuzhan Kılınçel

Alpha Psychiatry 2026, 27(1), 46205; https://doi.org/10.31083/AP46205

Abstract

Download

230

Reducing Disparities and Improving Mental Health for Transgender Persons

Open Access 25 Feb 2026Expert Opinion

Reducing Disparities and Improving Mental Health for Transgender Persons

Osborne F.X. Almeida, Pedro Morgado

Alpha Psychiatry 2026, 27(1), 45278; https://doi.org/10.31083/AP45278

Abstract

Download

506

ERP Decoding Analysis of Visual Working Memory Processes in Schizophrenia

Open Access 25 Feb 2026Original Article

ERP Decoding Analysis of Visual Working Memory Processes in Schizophrenia

Zhongsi Wang, Chunlei Liu, Yuyan Jing, Zhenzhen Yao, Min Chen

Alpha Psychiatry 2026, 27(1), 42597; https://doi.org/10.31083/AP42597

Abstract

Download

149

Evaluation of Short Term and Long Term Subjective and Objective Cognitive Outcomes Following ECT for Depression in a Naturalistic Ambulatory Setting: A Cohort Study

Open Access 3 Feb 2026Original Article

Evaluation of Short Term and Long Term Subjective and Objective Cognitive Outcomes Following ECT for Depression in a Naturalistic Ambulatory Setting: A Cohort Study

Sarah A. Goegan, Gary M. Hasey, Jelena P. King, Bruno J. Losier, Peter J. Bieling, Margaret C. McKinnon, Heather E. McNeely

Alpha Psychiatry 2026, 27(1), 45286; https://doi.org/10.31083/AP45286

Abstract

Download

317

Interrelationships Between Self-Injury Addiction, Traumatic Experiences, and Rumination Among Adolescents With Non-Suicidal Self-Injury: A Network Analysis

Open Access 3 Feb 2026Original Article

Interrelationships Between Self-Injury Addiction, Traumatic Experiences, and Rumination Among Adolescents With Non-Suicidal Self-Injury: A Network Analysis

Shijian Wang, Lin Zhao, Doudou Zheng, Linghua Kong, Jingya Li, Ying Yang

Alpha Psychiatry 2026, 27(1), 44340; https://doi.org/10.31083/AP44340

Abstract

Download

368

Structural Alterations and Cognitive Impairment in Late-Onset Depression: A Reverse Correlation Analysis

Open Access 3 Feb 2026Original Article

Structural Alterations and Cognitive Impairment in Late-Onset Depression: A Reverse Correlation Analysis

Yujie Wu, Naikeng Mai

Alpha Psychiatry 2026, 27(1), 44585; https://doi.org/10.31083/AP44585

Abstract

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319

Rethinking Autism as an Affective-Empathy Disorder

Open Access 3 Feb 2026Editorial

Rethinking Autism as an Affective-Empathy Disorder

Sergio Machado, Flávia Paes, João Lucas Lima

Alpha Psychiatry 2026, 27(1), 45867; https://doi.org/10.31083/AP45867

(This article belongs to the Special Issue Twenty-five Years at the Alpha Psychiatry Progresses on Psychiatry)

Download

351

Clinical Factors and Serum Biomarkers Associated With Major Depressive Disorder in Adolescents With and Without Nonsuicidal Self-Injury: A Comparative Cross-Sectional Study

Open Access 2 Feb 2026Original Article

Clinical Factors and Serum Biomarkers Associated With Major Depressive Disorder in Adolescents With and Without Nonsuicidal Self-Injury: A Comparative Cross-Sectional Study

Shengjiao Zhao, Xiaodan Dong, Jiahui Lu, Yanyan Wu, Ping Fang, Yu Zhang, Yujian Mou, Haiyan Xie

Alpha Psychiatry 2026, 27(1), 44160; https://doi.org/10.31083/AP44160

Abstract

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233

Open Access 2 Feb 2026Study Protocols

Yange Wei, Shanyuan He, Peng Luo, Rongxun Liu, Hanshuo Su, Zengyuan Shen, Shuqi Feng, Yanran Wu, Guangjun Ji, Wei Zheng, Fei Wang, Chuansheng Wang

Alpha Psychiatry 2026, 27(1), 46768; https://doi.org/10.31083/AP46768

(This article belongs to the Special Issue Schizophrenia: From Mechanisms to Clinical Studies)

Abstract

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486

Is Happiness a Possible Outcome for People With Schizophrenia?

Open Access 2 Feb 2026Editorial

Is Happiness a Possible Outcome for People With Schizophrenia?

Ilaria Riboldi, Giuseppe Carrà

Alpha Psychiatry 2026, 27(1), 46244; https://doi.org/10.31083/AP46244

Download

243

Insights from Tracing the Evolution of Automated Digital Mental Health Interventions in China

Open Access 12 Jan 2026Editorial

Insights from Tracing the Evolution of Automated Digital Mental Health Interventions in China

Jin Han

Alpha Psychiatry 2026, 27(1), 49906; https://doi.org/10.31083/AP49906

Download

435

Cognitive Impairment and Non-Invasive Neuromodulation Interventions in Bipolar Disorder: A Narrative Review of Current Status and Future Directions

Open Access 12 Jan 2026Review

Cognitive Impairment and Non-Invasive Neuromodulation Interventions in Bipolar Disorder: A Narrative Review of Current Status and Future Directions

Guilan Sun, Tongjie Zhuang, Minmin Wang, Xiaomei Zhang

Alpha Psychiatry 2026, 27(1), 42381; https://doi.org/10.31083/AP42381

Abstract

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562

Open Access 8 Jan 2026Original Article

Can-Jin Deng, Sha Nie, Rong Zeng, Jian-Xin Mai, Xiong Huang, Shi-Chao Xu, Xin-Hu Yang, Qing-Bin Zeng, Xing-Bing Huang, Wei Zheng

Alpha Psychiatry 2026, 27(1), 39942; https://doi.org/10.31083/AP39942

Abstract

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437