Dear Colleagues,

Applied neuroimaging is a rapidly developing field of radiology with both clinical and research applications. Recent years have seen an explosion in high-impact neuroscience manuscripts capitalizing on advanced neuroimaging techniques to test study hypotheses. The quantitative pipelines of a range of open-source and commercial software enable the meticulous evaluation of physiological and pathological processes and have been implemented across a spectrum of neurological and psychiatric conditions. Despite the differences in specific imaging techniques, the shared inspiration of applied imaging studies is the detection, characterization and critical interpretation of subtle pathologic changes. These changes in vivo complement clinical observations, support prevailing views on disease mechanisms and often track changes longitudinally. Seminal papers in recent years have captured presymptomatic changes in mutation carriers, revealed propagation patterns in neurodegenerative conditions, confirmed treatment effects in clinical trials and contributed novel academic insights. The objective of this special issue is to solicit manuscripts involving diverse neurological and psychiatric conditions to showcase the potential of applied imaging in both research and clinical settings.

Dr. Foteini Christidi and Dr. Efstratios Karavasilis
Guest Editors