- Academic Editor
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Objective: An extract of Xanthoceras sorbifolium Bunge (XSB) oil called
nervonic acid (NA) was studied for its potential to ameliorate oxidative stress
and inflammation in people living with Parkinson’s disease (PD).
Recrystallization column chromatography was performed to isolate NA from the XSB
oil. Twenty-five C57BL/6 mice (8–10 weeks old) were randomly assigned to one of
five groups (control, model, low, medium, and high dosage). Methodology:
Except for the control group, all of the experimental animals received an
intraperitoneal injection of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
The next phase was administering varied doses of NA produced from XSB oil to
mice. Control, model, low-dose, medium-dose, and high-dose groups were created at
random from SH-SY5Y and PC-12 cell cultures. Our study’s control groups exhibited
typical normative conduct. Research: Polymerase chain reaction (PCR) was
used to examine oxidative stress (OS) and inflammatory factors (IFs) in cells. By the time recrystallization column chromatography had finished its
analysis, the concentration of NA had increased by a factor of roughly 26.
Results: The model and high-dose groups showed similar levels of
apoptosis in behavior (p
