IMR Press / JIN / Volume 20 / Issue 1 / DOI: 10.31083/j.jin.2021.01.277
Open Access Case Report
A patient with acute myeloid leukemia presented with a superior sagittal sinus thrombosis as the first manifestation of Trousseau syndrome
Yi Bu1,†Na Wei2,†Yan Liu3Jing-Zhe Han2,*
Show Less
1 Department of Neurology, Affiliated Hospital of Chengde University, Chengde, 067000 Hebei, P. R. China
2 Department of Neurology, Harrison International Peace Hospital, Hengshui, 053000 Hebei, P. R. China
3 Department of Otorhinolaryngology, Harrison International Peace Hospital, Hengshui, 053000 Hebei, P. R. China
*Correspondence: (Jing-Zhe Han)
These authors contributed equally.
J. Integr. Neurosci. 2021, 20(1), 153–155;
Submitted: 14 September 2020 | Revised: 28 November 2020 | Accepted: 4 December 2020 | Published: 30 March 2021
Copyright: © 2021 The Authors. Published by IMR Press.
This is an open access article under the CC BY 4.0 license (

This paper reports a case of Trousseau syndrome with intracranial venous sinus thrombosis as the first manifestation, which is relatively rare in the clinic. A 44-year-old female patient presented with a blurred vision of the visual substance for 2 months, and the condition was aggravated with a headache for 10 days. The final diagnosis was intracranial venous sinus thrombosis and acute myeloid leukemia subtype M2. Anticoagulant + intra-arterial regimen (cytarabine + igdabistar) was given, and the patient’s headache and blurred vision were gradually restored. After 2 courses of chemotherapy, acute myeloid leukemia subtype M2 was in complete remission. After 6 months of follow-up, headache and the blurred vision disappeared, leukemia did not recur, limb vascular ultrasound was screened regularly, and no new vascular embolism disease occurred.

Trousseau syndrome
Acute myeloid leukemia subtype M2
Intracranial venous sinus thrombosis
Cerebrovascular disease
Fig. 1.
Back to top