Dear Colleagues,

Cellular development and cell fate specification are precise events regulated by different mechanisms that cooperate to maintain the correct pattern of gene expression. Accordingly, extracellular signals including changes in the microenvironment and mechanical stimuli are able to trigger the fine regulation of these transcriptional networks to control cell fate decisions such as survival, proliferation or differentiation.

This Special Issue will publish interesting original and review articles concerning the biochemical and molecular biology of cell survival, death and differentiation, particularly those focusing on regulation of the transcriptional network by the extracellular microenvironment. Regulation of protein and gene expression patterns in cellular or animal models will also be considered of particular interest.

Dr. Simona Daniele and Dr. Rebecca Piccarducci
Guest Editors