IMR Press / CEOG / Volume 49 / Issue 8 / DOI: 10.31083/j.ceog4908186
Open Access Original Research
Association between Trimester-Specific Gestational Weight Gain Rate and Maternal and Neonatal Outcomes
Show Less
1 Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, 215000 Suzhou, Jiangsu, China
2 Department of Obstetrics and Gynecology, The Fifth People's Hospital of Wujiang District, 215000 Suzhou, Jiangsu, China
3 Department of Obstetrics and Gynecology, Suzhou Municipal Hospital, 215008 Suzhou, Jiangsu, China
*Correspondence: (Bing Han); (Liping Zhu)
These authors contributed equally.
Academic Editors: Johannes Ott and Michael H. Dahan
Clin. Exp. Obstet. Gynecol. 2022, 49(8), 186;
Submitted: 17 March 2022 | Revised: 12 May 2022 | Accepted: 23 May 2022 | Published: 3 August 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: To investigate the associations of adjusting gestational weight gain rate (GWGr) with maternal and neonatal outcomes. Methods: We analyzed 6235 singleton pregnancies among women with normal pre-pregnancy body mass index at two medical centers in China during 2016~2018 to figure out whether pregnancy outcomes could be improved by adjusting GWGr timely when the first-trimester weight gain rate (GWGr-1) and/or the second-trimester weight gain rate (GWGr-2) were inappropriate. Results: When GWGr-1 was excessive, excessive GWGr during the second and third trimesters of pregnancy (late GWGr) was associated with a higher risk of cesarean section (CS), postpartum hemorrhage (PPH), obstructed and prolonged labor and large for gestational age (LGA), and inadequate late GWGr was associated with a lower prevalence of CS and hypertensive disorders of pregnancy (HDP). In pregnancies with inadequate GWGr-1, excessive late GWGr was related to a higher rate of CS, LGA and HDP. Among women with adequate GWGr-1, excessive GWGr in the third trimester (GWGr-3) was positively associated with CS, HDP, and obstruction and prolongation of labor if their GWGr-2 was excessive, and excessive GWGr-3 was associated with a higher risk of CS even though tFheir GWGr-2 was inadequate. Conclusions: Prompt control of GWGr, even during late pregnancy, was beneficial to improving pregnancy outcomes.

gestational weight gain
pregnancy complications
pregnancy outcome
H2019010/Jiangsu Commission of Health
Back to top