IMR Press / CEOG / Volume 47 / Issue 5 / DOI: 10.31083/j.ceog.2020.05.5398
Open Access Original Research
Effect of prenatal depression during late pregnancy on maternal and neonatal outcomes
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1 Department of Obstetrics, Women’s Hospital, School of Medicine, Zhejiang University, Zhejiang, P.R. China
2 Medical School, Hangzhou Normal University, Zhejiang, P.R. China
*Correspondence: FENG); LUO)
Clin. Exp. Obstet. Gynecol. 2020, 47(5), 681–686;
Submitted: 8 September 2019 | Accepted: 27 May 2020 | Published: 15 October 2020
Copyright: © 2020 Xu et al. Published by IMR press
This is an open access article under the CC BY 4.0 license

Aim: To determine whether prenatal depression during late pregnancy affect maternal and neonatal outcomes. Methods: The clinical data of 595 pregnant patients in our hospital during January 2016 to December 2017 were studied. These participants were assigned into three groups as mild-to-moderate depression group, severe depression group and non-depression group according to the Edinburgh postnatal depressive scale (EPDS). Results: Compared with the women without depression or with mild-to-moderate depression, pregnant patients with severe depression were likely to suffer from preterm birth (p < 0.05). There was no association between the mild-to-moderate depression, severe depression group and the non-depression group about neonatal outcomes (all p > 0.05). Conclusion: Severe prenatal depression during late pregnancy is significantly associated with increased risk of preterm birth, while mild-to-moderate prenatal depression would not affect maternal and neonatal outcomes.

Prenatal depression
Late pregnancy
Preterm birth
81571447/National Natural Science Foundation of China
2018C03010/Key Research Project of Zhejiang Province
2018RC005/Construction of Medical Core Subjects and Innovation Platform in Zhejiang Province Grant
Figure 1.
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