IMR Press / CEOG / Volume 46 / Issue 3 / DOI: 10.12891/ceog4794.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Cytogenetic analysis of miscarriage materials of couples with recurrent pregnancy loss in a tertiary center
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1 Department of Medical Genetics, Ege University School of Medicine, Izmir, Turkey
2 Department of Obstetrics and Gynecology, Ege University School of Medicine, Izmir, Turkey
*Correspondence: (ISMET HORTU)
Clin. Exp. Obstet. Gynecol. 2019, 46(3), 423–426;
Published: 10 June 2019

A pregnancy loss (miscarriage) is defined as the spontaneous demise of a pregnancy before the fetus reaches viability. The term therefore includes all pregnancy losses from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss (RPL) is defined as two or more losses of the pregnancy. There are many proposed reasons; however in a prominent portion of cases, the reason remains unclear. Chromosomal abnormalities have an important place in recurrent pregnancy loss. Numerical and structural abnormalities constitute a significant cause. The purpose of this study was to assess the chromosomal abnormality of 490 chorionic villus samples of the couples who experienced RPL and to provide data for both clinicians and genetic counsellors.

Recurrent pregnancy loss
Cytogenetic abnormalities
Figure 1.
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