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Original Research
Echogenic intracardiac focus in fetus and association with maternal respiratory tract infection in Shanghai, China
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1
The International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai
2
Department of Anatomy and Neurobiology, Tongji University School of Medicine, Shanghai (China)
Clin. Exp. Obstet. Gynecol. 2015, 42(6), 763–766;
https://doi.org/10.12891/ceog1988.2015
Published: 10 December 2015
Abstract
Purpose of investigation: To evaluate the association between fetal echogenic intracardiac focus (EIF) and maternal respiratory tract infections (RTI) during gestation. Materials and Methods: Fetal echocardiography was performed on 1,720 pregnant women (1,723 fetuses), and 205 of them showed evidence of fetal EIF. Other 245 pregnancies without fetal EIF were selected randomly as a control group. Comparison was undertaken to evaluate the difference between these two groups, and the possible association between EIF and maternal RTI. Results: EIF was present in 11.9% of the examined fetuses, and the presence of fetal EIF with maternal RTI was significantly higher (p < 0.05) than those without RTI. Multivariate logistic regression correction of RTI showed that the likelihood of EIF was 49 fold higher in pregnant women with RTI than without it (odds ratio [OR] = 49.958, 95% confidence interval [CI], 25.973~96.092, p < 0.05). Conclusions: Fetal EIF is suggested to be associated with maternal RTI during gestation in the present study population.
Keywords
Ultrasound
Fetus
Echogenic intracardiac focus
Prenatal diagnosis
Respiratory tract infection