IMR Press / CEOG / Volume 31 / Issue 4 / pii/2004082

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Malignant neoplasms arising in endometriosis: Clinicopathological study of 14 cases

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1 Pathology Laboratory, Areteion Hospital, Athens Medical School Athens (Greece)
2 2nd Clinic of Obstetrics and Gynecology, Areteion Hospital, Athens Medical School Athens (Greece)
3 2nd Clinic of Surgery, Areteion Hospital, Athens Medical School Athens (Greece)
Clin. Exp. Obstet. Gynecol. 2004, 31(4), 302–304;
Published: 10 December 2004

During the last 15-year period in our laboratory, 14 cases of malignant change of endometriosis were diagnosed in women 37-70 years of age. Seven cases were adenocarcinomas, one case was an adenosarcoma and six cases presented the morphology of endome­trial stromal sarcoma. Eleven cases developed in various sites of the genital system (5/11 in the ovaries, 3/11 in the uterus 2/11 in the vagina, 1/11 in the tubal wall) and three cases in extragenital sites (1/3 in the omentum, 1/3 in the pelvis, 1/3 in the colon). Immunohistochemical investigation for the expression of cytokeratines, vimentin, hormonal receptors, E-cadherin, desmine and smooth muscle actin was performed by a streptavidin-biotin method. The immunopathology profile and follow-up results after therapy are presented.

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